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RISS 인기검색어
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- 저자 : 정상섭 ( Jeong Sang Seob ) (검색결과 2 건)
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유내춘 ( Yu Nae Chun ),이현철 ( Lee Hyeon Cheol ),양동규 ( Yang Dong Gyu ),정춘희 ( Jeong Chun Hui ),안광진 ( An Gwang Jin ),이은직 ( Lee Eun Jig ),임승길 ( Im Seung Gil ),허갑범 ( Heo Gab Beom ),정상섭 ( Jeong Sang Seob ),정태섭 대한내과학회 1992 대한내과학회지 Vol.42 No.3
Pituitary adenoma, Cushing`s disease is characterized by typical clinical symptoms like bilateral adrenal hyperplasia and adrenal cortex hyperfunctioning and is usually small in size, making it very difficult to detect by conventional plain skull X-ray and recently developed high resolution brain computed tomogram (CT) and magnetic resonance image (MRI) are reported to detect only 30% to 50% of all cases. Currently, detection of hormone levels through inferior petrosal sinus blood sampling is available, facilitating the diagnosis of pituitary microadenoma. This clinical study was designed to detect the patients with Cushing`s disease who were hospitalized in Yonsei University Severance hospital from 1988 to 1990. And all of them are highly suggestive of Cushing`s diseas by clinical and endocrinological findings, but can not be ascertained by radiological test. In a total 7 patients were engaged, and by using bilateral inferior petrosal sinus sampling and hormone assay, the results are as follows. 1) Low dose dexamethasone suppression test did not show suppression in all patients performed the test but high dose dexamethasone suppression test showed suppression in six patients out of seven (85.7%). 2) Basal plasma ACTH level showed normal in four out of seven patients (57.1%). 3) Pituitary CT scan sowed normal or equivocal findings in six patients except one and MRI showed low density in two cases among five. 4) The plasma ACTH levels of inferior petrosal sinus on the ipsilateral side to the tumor were significantly increased in four cases out of seven (57.1%) compared to those of contralateral side but remaining one case showed significant ACTH increase on CRF stimulation test in tumor side and remaining two cases were found to be a midline tumor after surgery. 5) The prolactin and growth hormone levels of inferior petrosal sinus on the ipsilatral side to the tumor were increased in five cases (71.4%) and in three (50%) of six cases respectively compared to those of contralateral side. 6) After surgery, five patient`s biochemical findings showed complete remission but one patient was found to be recurred by OPD follow up. It was concluded that the hormone assay by inferior petrosal sinus sampling could provide important information about diagnosis and tumor lateralization in Cushing`s disease which was biochemically and radiologically inconclusive.
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김광수,정상섭 경운대학교 산업기술연구소 2001 産業技術硏究論文誌 Vol.4 No.1
In this paper, estimation of Jah-RASTA coefficients based on density distribution of noise level for environmental noise reduction to improve the performance of word recognition system is proposed. This technique verified through word recognition tests. By results, about 25% recognition rate improvements obtained. Especially, even at very low SNR, it show the better results compared to methods.
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