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RISS 인기검색어
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- 저자 : 전인기 ( Jee Bum Lee (검색결과 4 건)
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이지범 ( Jee Bum Lee ),이형우 ( Hyoung Woo Lee ),이승철 ( Seung Chull Lee ),원영호 ( Young Ho Won ),전인기 ( Inn Ki Chun ) 대한피부과학회 1996 대한피부과학회지 Vol.34 No.1
Unilateral keratosis follicularis is considered a localized variant of Darier's disease and should be included in the differential diagnosis of diseases with zosteriform keratotic eruptions. It is characterized by the unilateral linear lesions in multiple locations, increased irritation by sweating, lack of solar aggravation, and negative family history. Histopathologic findings reveal acantholytic dyskeratosis similar to a generalized Darier's disease. We report a case of unilateral keratosis follicularis in a 68-year-old man, who presented with unilateral flesh-colored keratotic papules on the left axilla and inguinal area. He was effectively treated with oral 13-cis-retinoid acid (isotretinoin). (Kor J Dermatol 1996;34(1): 127-131)
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당뇨병 환자의 화상 창상에서 발생한 원발성 피부 아스페르길루스증
이지범 ( Jee Bum Lee ),이승철 ( Seung Chul Lee ),원영호 ( Young Ho Won ),전인기 ( Inn Ki Chun ) 대한피부과학회 1996 대한피부과학회지 Vol.34 No.2
A 68 year-old man with uncontrolled diabetes mellitus was presented with a single 4 * 2.5cm sized undermined purulent ulcer with a black eschar surrounded by erythematous indurated plaques on the dorsurn of the his left foot. Fungal hyphae were found in the deep dermis of the skin biopsy specimen. Aspergillus flavus was cultured and isolated by repeated fungal cultures from the pus and tissue pieees of skin biopsy specimens. Wide surgical debridement followed by a skin graft, and adjuvant antifungal treatment applied twice did not cure the skin lesion. We report a case of cutaneous aspergillosis showing a poor outcome in spite of surgical therapy and antifungal medication. (Kor J Dermatol 1996;34(2): 350-354)
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최근 10년간 피부 편평 세포암에 관한 임상적 및 병리조직학적 고찰
이지범,이승철,원영호,전인기 ( Jee Bum Lee,Seung Chul Lee,Young Ho Won,Inn Ki Chun ) 대한피부과학회 1996 大韓皮膚科學會誌 Vol.34 No.5
Background: Cutaneous squarnous cell carcinoma(SCC) is the first or second to basal cell carci- noma in prevalence and its in<:idence is increasing in Korea. The biology of squamous cell carci- noma is reviewed under the broad areas of incidence, site, etiology, histologic patterns, metastatic rate, and therapeutic modalities. Objective . The purpose of this study is to investigate recent trends of cutaneous SCC in clini- cal and histopathological aspects in Korea. Methods : Both clinical and histopathological studies from the biopsy specimens were performed in 68 cases of SCC who visited the Department of Dermatology, Chonnam University Hospital during the last 10 years from I 985 to 1994. Results : 1. The etiologic factors were found in 29 cases amongst a total of 68 cases. The most common etiologic factor was a burn scar(13 cases). The other etiologic factors followed in this order, actinic keratosis(5 cases), chr!>nic ulcers and smoking(3 cases each), trauma induced scars(2 cases), Bowens disease and ch,onic radiodermatitis and drugs(1 case each). 2. In histopathologic classification, common differentiated types showing various st.ages of different,iation counted for 60 cases. Less commonly. acantholytic(1 case), spindle(2 cases), and verrucous(5 cases) were observed. 3. In determining the relatiorlship between the clinical aspects and rnetastasis, several etiologic factor s were found; more thar! 1 year in duration, more t,han 2cm in diameter, mucosal lesions such as lower lip and penis, and SCC caused from the previous burn scar or chronic ulcer. In terms of the relationship between histopathologic aspects and metastasis, the depth of cell invasion was more important than the di',gree of differentiation in determining the potency of metastasis. Conclusion . This study reve,iled that the incidence of cutaneous squmous cell car cinoma in Korea is increasing, and dermatologists should know the importance of the tumor in both diagno- sis and treatment. (Kor J Derrrlatol 1996;34(5): 775-783)
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조갑진균증에서 Ciclopirox 8 Nail Lacquer의 치료효과
원영호 ( Young Ho Won ),이지범 ( Jee Bum Lee ),이승철 ( Seung Chul Lee ),전인기 ( Inn Ki Chun ) 대한피부과학회 1995 대한피부과학회지 Vol.33 No.6
Background : Ciclopirox 8% nail lacquer is a new topical antifungal agent which is charact.er ized by excellent penetration into the nail plate to the infected koratin and remains there for a prolonged period. We per formed a st,udy to assess the therapeutic efficacy and safety of ciclopirox 8% nail lacquer in the treatment of onychomycoses. Methods : We used 20 satients wit,h onychomycoses, which was confirmed by KOH ancl fungus culture. The ciclopirox nail lacquer was applied once daily for 1 month, and followed by two times weekly for the next 5 months. The clinical observat.ion was perforrned every month for any clinical improvement and side-dffects. The involved percent of a target nail was measured by using a adhesive tape at.ached to the selected nail plate. All involved nails(n=68) were also evaluated by a severity score(severe>50%. moderate 25-50%, mild<25%). Results : Seventeen patients were finally assessed because of the deletion of 3 patients througl loss of contact. The involved percent of target nail was significantly decreased from 57.4% at baseline to 27.9% througli the 6 month-treatment(p<0.01, ANOVA). The total reduced precent of target nail involvement at the end of the treatment was 52+22% on average. The precent of severly involved nail(>50%) in all 68 involved nails was also decreased from 56% at baseline to 7% by the end of the treatment The mycologieal cure rate was 82.4% by the end of the treatment. The overall efficaor assessed by the physician and patients was improvement by 82.4% Tolerability was excellent or good in all patients, but cosmetic acceptance was good or excellen by 53%. Only one patient complained of a prickling sensation, but no systemic adverse effect were found, Conclusion : These data suggest that ciclopirox 8% nail lacquer may be safe and effective ir the treatment of onychomvcoses. (Kor J Dermatol 1995;33(6): 1079-1084)
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