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임형택,박히준,장지련,최일환,이석찬,김대수,신희섭,임사비나,Lim, Hyung-Taeck,Park, Hi-Joon,Jang, Ji-Ryeon,Choi, Il-Hwan,Lee, Seok-Chan,Kim, Dae-Soo,Shin, Hee-Sup,Lim, Sa-Bi-Na 경락경혈학회 2004 대한침구의학회지 Vol.21 No.2
Objective : Acupuncture has been used for treatment of numerous disorders, especially for pain control in Oriental Medicine. However, the mechanism of pain control by acupuncture was not clear until now. This study was performed to prove analgesic mechanism of acupuncture treatment at acupoint $ST_{36}$ by observing the changes of abdominal pain and c-Fos expression in the thalamus. Methods : Abdominal pain was induced by acetic acid, and the changes of writhing reflex after acupuncture treatment on $ST_{36}$ and non-acupoints were measured. c-Fos immunohistochemistry was also performed to study the changes of the neuronal activity in the thalamus. Results : The writhing reflex decrease significantly after acupuncturing at $ST_{36}$ compared with control group(p<0.05). The changes of the writhing reflex by non-acupoint acupuncture treatment also showed significant decrease compared with control group(p<0.05). c-Fos expression in the thalamus, especially periventricular part was significantly decreased after acupuncturing as $ST_{36}$ compared with control groups(p<0.05). Conclusion : This study shows that the acupuncture has the analgesic effect in the abdominal pain induced by acetic acid and the thalamus might be a important area for this mechanism.
임사비나 ( Sa Bi Na Lim ),임형택 ( Hyung Taeck Lim ),박히준 ( Hi Joon Park ),장지련 ( Ji Ryeon Jang ),최일환 ( Il Hwan Choi ),이석찬 ( Seok Chan Lee ),김대수 ( Dae Soo Kim ),신희섭 ( Hee Sup Shin ) 대한경락경혈학회 2004 Korean Journal of Acupuncture Vol.21 No.2
Objective: Acupuncture has been used for treatment of numerous disorders, especially for pain control in Oriental Medicine. However, the mechanism of pain control by acupuncture was not clear until now. This study was performed to prove analgesic mechanism of acupuncture treatment at acupoint ST36 by observing the changes of abdominal pain and c-Fos expression in the thalamus. Methods: Abdominal pain was induced by acetic acid, and the changes of writhing reflex after acupuncture treatment on ST36 and non-acupoints were measured. c-Fos immunohistochemistry was also performed to study the changes of the neuronal activity in the thalamus. Results: The writhing reflex decrease significantly after acupuncturing at ST(36) compared with control group(p<0.05). The changes of the writhing reflex by non-acupoint acupuncture treatment also showed significant decrease compared with control group(p<0.05). c-Fos expression in the thalamus, especially periventricular part was significantly decreased after acupuncturing at ST(36) compared with control groups(p<0.05). Conclusion: This study shows that the acupuncture has the analgesic effect in the abdominal pain induced by acetic acid and the thalamus might be a important area for this mechanism.
임사비나,임형택,박히준,장지련,최일환,이석찬,김대수,신희섭 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2004 東西醫學硏究所 論文集 Vol.2004 No.-
Objective : Acupuncture has been used for treatment of numerous disorders, especially for pain control in Oriental Medicine. However, the mechanism of pain control by acupuncture was not clear until now. This study was performed to prove analgesic mechanism of acupuncture treatment at acupoint ST_(36) by observing the changes of abdominal pain and c-Fos expression in the thalamus. Methods : Abdominal pain was induced by acetic acid, and the changes of writhing reflex after acupuncture treatment an ST_(36) and non-acupoints were measured. c-Fos immunohistochemistry was also performed to study the changes of the neuronal activity in the thalamus. Results : The writhing reflex decrease significantly after acupuncturing at ST_(36) compared with control group(p<0.05). The changes of the writhing reflex by non-acupoint acupuncture treatment also showed significant decrease compared with control group(p<0.05). c-Fos expression in the thalamus, especially periventricular part was significantly decreased after acupuncturing at ST_(36) compared with control groups(p<0.05). Conclusion : This study shows that the acupuncture has the analgesic effect in the abdominal pain induced by acetic acid and the thalamus might be a important area for this mechanism.