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        후부다형각막이상증의 공초점주사현미경소견

        최범석,박영민,이종수.Beom Seok Choi. MD. Young Min Park. MD. Jong Soo Lee. MD. PhD 대한안과학회 2013 대한안과학회지 Vol.54 No.11

        Purpose: To analyze the features of corneal tissue in patients with posterior polymorphous corneal dystrophy (PPMD) using in vivo confocal microscopy (IVCM). Case summary: Three patients with clinically diagnosed PPMD were examined using IVCM. Cross-sectioned corneal images of the corneal epithelium, Bowman’s layer, stromal layer, Descemet’s membrane, and endothelium were evaluated. IVCM demonstrated a depressed crater-like lesion, hyper-dense streak-like lesion, and surface irregularity of the corneal endothelium. Endothelial hypo-reflective vesicular and band-like lesions were also found. Pleomorphism and polymegathism were present with guttae and hyper-reflective endothelial nuclei. Conclusions: IVCM is a non-invasive and effective tool to diagnose PPMD. J Korean Ophthalmol Soc 2013;54(11):1783-1787

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        공초점주사현미경에 의한 푹스각막이상증의 각막조직소견

        박영민,최범석,이종수.Young Min Park. MD. Beom Seok Choi. MD. Jong Soo Lee. MD. PhD 대한안과학회 2013 대한안과학회지 Vol.54 No.9

        Purpose: To analyze the morphology and density of corneal tissue in patients with early stage Fuchs’ corneal endothelial dystrophy (FCED) by in vivo confocal microscopy (IVCM). Case summary: Each layer of the cornea in 2 patients with early-stage FCED was examined with IVCM (ConfoScan 4.0, NIDEK, Co. Ltd., albignasego, Italy). Cross-sectioned corneal images of the corneal epithelium, Bowman’s layer, stromal layer, Descemet’s membrane, and endothelium were evaluated. Corneal epithelium, Bowman’s layer, and anterior stroma of both patients showed no abnormalities. Case 1 was diagnosed as Stage 1 FCED, demonstrating typical changes including pleomorphism, polymegathism, and the presence of guttae in the corneal endothelial layer. Case 2 was diagnosed as Stage 2 FCED, showing several hyper-reflective whitish dots in the posterior stroma, hypo-reflective vertical strands in the stroma adjacent to Descemet’s membrane, and pleomorphism, polymegathism, and guttae in the corneal endothelial layer. Conclusions: IVCM is a non-invasive and effective tool to diagnose early-stage FCED.

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