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상부위장관 내시경검사 전처치제로 투여한 Rociverine Citrate 의 효과에 관한 관찰
함준수(Joon Soo Hahm),기춘석(Choon Suhk Kee),박경남(Kyung Nam Park),이민호(Min Ho Lee),이종철(Jong Chul Rhee),윤호주(Ho Ju Yung) 대한소화기학회 1988 대한소화기학회지 Vol.20 No.1
N/A A new synthetic smooth muscle-relaxant, Rociverine citrate (Danapen), was tested for spasmolytic action on the smooth musculature of the pyloric sphincter against Hyoscine butylbromide. The total number of subjects was 262 patients and 10 mg of Rociverine citrate were intramuscularly given in 128 cases and 20 mg of Hyoscine butylbrornide were given in the 134 cases. The drug effect were assessed on the degree of opening of the pyloric sphincter and the endoscopists rating of drug performance. The results were as follows; 1) About the pyloric sphincter status, 116 cases (90.6%) of Rociverine citrate premedicated group and 115 cases (85.8%) of Hyoscine butylbromide premedicated group and 115 cases (85.8%) of Hyoscine butylbromide premedicated group showed above than fair response. 2) The ratings of examination procedure by the endoscopist were very good in 76.6%, good in 20.3%, fair in 2.3%, and ineffective in 0.8%, in Rociverine premedicated group and very good in 73.1%, good in 22.4%, fair in 3.7%, and ineffective in 0.8%, in Hyoscine butylbromicle premedicated group. 3) No adverse effects were noted in Rociverine citrate group. Thus, we concluded that the Rociverine citrate is an active drug as a premedication drug for upper endoscopic examination.
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