http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
양유영(Yu-Young Yang),박상성(Sang-Sung Park),신영근(Young-Geun Shin),장동식(Dong-Sik Jang) 한국정보기술학회 2009 Proceedings of KIIT Conference Vol.2009 No.-
산업이 고도화됨에 따라 빠르게 변하는 시장과 기술경쟁의 가속화는 사회 구성원의 경쟁을 심화시키고 있다. 이 같은 현실은 여러 경제주체들이 시장에서의 생존 및 우위선점을 위한 대응책을 찾게 하였고, 이러한 노력 중 하나가 미래 환경에 대한 예측이었다. 이에 다양한 분야에서 정확한 예측 결과를 얻기 위한 기법 연구가 선행되어 왔으며 본 논문에서는 예측기법에 대한 동향을 파악하기 위해 기존에 주로 사용되는 예측기법들을 제시하고 성능을 비교 분석한 뒤, 개선된 예측기법 개발을 위한 연구 방향을 제안한다. As more capital-intensive industry develops, the rapidly changing market and accelerating the technology race has caused intensified competition between members of society. In such a situation, most of economic participants can''t help finding countermeasures to survive and preoccupy in the market, and forecasting is one way to provide against a precarious situation. The various forecasting methods for obtaining precise results has been studied in various fields. This paper presents and compares the performance of the existing techniques in order to research the trend of forecasting methods, then suggest a desirable research direction for developing an advanced forecasting methods.
양유영(Yang, Yu-Young),박상성(Park, Sang-Sung),신영근(Shin, Young-Geun),장동식(Jang, Dong-Sik) 한국산학기술학회 2010 한국산학기술학회논문지 Vol.11 No.4
외환위기 이후 본격적으로 시작된 외국계 대형 은행의 국내 진출 및 선진 금융상품의 수입은 국내 은행 산 업 구조와 환경을 변화시키고 경쟁을 가속화시켰다. 앞으로 일어날 변화 및 추세에 대한 정확한 예측은 경쟁이 치열 한 환경에서 국내의 은행이 생존하고 발전하기 위해 필수적인 요소이며 그 중에서도 대출 신청 고객에 대한 승인 여 부에 대한 예측은 대출 상품이 은행 경영에 있어 가장 큰 비중을 차지하는 수익의 원천이자 신용 리스크 관리의 중 심이 된다는 점에서 큰 의미가 있다. 따라서 본 논문에서는 대출 심사 결과의 예측 정확성을 높이기 위한 방법을 제 시하고자 한다. 수행 단계로는 상관관계 분석과 특징선택 기법을 통해 대출승인 결과에 유의한 영향을 주는 예측변수 들을 선별하고 선별된 변수로 2-Step 군집화 기법을 통해 고객을 군집화 하였다. 이후 각 군집에 LR, NN, SVM 기법 을 활용하여 구축한 예측 모형을 적용하여 정확도가 가장 높은 모형을 찾아보았다. 최종적으로 기존 방식의 대출 심 사 모형에 LR, NN, SVM 예측 모형을 적용했을 때 산출된 결과와 제안한 모형의 결과를 비교하여 예측의 정확도를 평가하였다. Industry structure and environment of the domestic bank have been changed by an influx of large foreign-banks and advanced financial products when the currency crisis erupted in Korea. In a competitive environment, accurate forecasts of changes and tendencies are essential for the survival and development. Forecast of whether to approve loan applications for customer or not is an important matter because that is related to profit generation and risk management on the bank. Therefore, this paper proposes the method to improve forecast accuracy of loan underwriting. Processes in experiments are as follows. First, we select the predictor variables which affect significantly to the result of loan underwriting by correlation analysis and feature selection technique, and then cluster the customers by the 2-Step clustering technique based on selected variables. Second, we find the most accurate forecasting model for each clustering by applying LR, NN and SVM. Finally, we compare the forecasting accuracy of the proposed method with the forecasting accuracy of existing application way.
신규 플루오로퀴놀론계 DWP20367 의 흰쥐 및 개에서의 체내동태와 조직분포
심점순(Jeom Soon Shim),유영효(Young Hyo Yu),남권호(Kweon Ho Nam),박명환(Myung Hwan Park),공재양(Jae Yang Kong),조재열(Jae Youl Cho),한승희(Seung Hee Han),김병오(Byoung O Kim),정대영(Dae Young Jeong),이재욱(Jae Wook Lee),손호정(Ho Jun 한국응용약물학회 1997 Biomolecules & Therapeutics(구 응용약물학회지) Vol.5 No.3
The pharmacokinetics and tissue distribution of DWP20367 (1-cyclopropyl-6-fluoro-8-chloro-7-(2,7-diazabicyclo[3,3,0]oct-4-ene-7-yl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid), a novel fluoroquinolone, were examined in rats and beagle dogs after a single intravenous and oral administration. Analysis of DWP20367 in plasma, tissue, and urine was determined by both HPLC and microbiological assay (bioassay). The plasma concentration-time curves of the drug in rats and beagle dogs were biexponentially declined. The terminal halflife (t_(½β)) of the drug in rats was about 60.1 ±7.3 min (i.v.) and 61.3 ±12.4 min (p.o.) in bioassay, and 86.3 ±19.8 min (i.v.) and 50.9±14.9 min (p.o.) in HPLC. In beagle dogs, half-life of the drug determined by bioassay was about 121.8±6.2 min (i.v.) and 111.0±7.6 min (p.o.). The volume of distribution at steady-state (Vd_(ss)) was 243.8±74.1 ml/kg (bioassay) and 339.2±84.3 ml/kg (HPLC) in rats, and 1587.5±536.9 ml/kg (bioassay) in beagle dogs. The total body clearance (Cl₁,) of DWP20367 was 3.4±0.4 ml/min/kg (bioassay) and 2.4±0.4 ml/min/kg (HPLC) in rats, and 12.3±1.0 ml/min/kg (bioassay) in beagle dogs, respectively. The extent of bioavailability after oral administration was 89.1 %(bioassay) and 79.9% (HPLC) in rats, and 78.7% (bioassay) in beagle dogs. Urinary recovery (24-h) assayed by bioassay was 0.7% (p.o.) and 1.2% (i.v.) in rats, and 0.8% (p.o.) and 1.0% (i.v.) in beagle dogs. In rats, 24-h fecal recovery determined by bioassay was 11.2% (p.o.) and 0.1% (i.v.). Rat and human serum protein binding ratios at 2 ㎍/ml were about 90∼91%. This drug determined by bioassay was also distributed by the order of liver, kidney, lung, heart, spleen and muscle 30 min after oral administration.
신규 플르오로퀴놀론계 항생물질인 DWP20373 의 흰쥐 및 개에서의 체내동태와 조직분포
심점순(Jeom Soon Shim),유영효(Young Hyo Yu),남권호(Kweon Ho Nam),박명환(Myung Hwan Park),공재양(Jae Yang Kong),조재열(Jae Youn Cho),한승희(Seung Hee Han),김병오(Byoung O Kim),김지연(Ji Yeon Kim),유은숙(Eun Sook Yoo),정대영(Dae Young 한국응용약물학회 1997 Biomolecules & Therapeutics(구 응용약물학회지) Vol.5 No.2
The pharmacokinetics and tissue distribution of DWP20373, a novel fluoroquinolone, were examined in rats and beagle dogs after a single intravenous and oral administration. Analysis of DWP20373 in plasma, tissue, and urine was performed by both HPLC and microbiological assay. The plasma drug concentration declined biexponentially both rats and beagle dogs. In the rats, the terminal drug elimination half-life (t_(½β)) was 64 min (IV) and 57 min (PO) by bioassay, and 76 min (IV) and 77 min (PO) by HPLC. Whereas, in beagle dogs, t_(½β) was 196 min (IV) and 350 min (PO). The volume of distribution at steady-state (Vd_(ss)) was 811 ml/kg (bioassay) and 2061 ml/kg (HPLC) in rats, and 2738 ml/kg (bioassay) in beagle dogs. The total body clearance (Cl₁) of DWP20373 was 10 ml/min/kg (bioassay) and 7 ml/min/kg (HPLC) in rats, and 11 ml/min/kg (bioassay) in beagle dogs. The extent of bioavailability after oral administration was 49% (bioassay) and 67% (HPLC) in rats, and 84% (bioassay) in beagle dogs. The 24-h urinary recovery, measured by bioassay, was 2.7% after oral dosing and 5.5% after intravenous dosing in rats. Serum protein binding ratio determined at 2 ㎍/㎖ was 78%. This drug was also distributed in tissues in the decreasing order of liver, kidney, spleen, lung, heart, and muscle determined at 30 min after oral administration.