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신상철,조정원 ( Sang Chul Shin,Cheong Weon Cho ) 한국약제학회 1997 Journal of Pharmaceutical Investigation Vol.27 No.1
N/A Nicotinic acid was mixed with glass powders such as controlled pore glass (CPG), glyceryl controlled pore glass (GPG) and glass beads (GB) at room temperature. The physicochemical properties of nicotinic acid in the various mixtures were examined by differential thermal analysis. X-ray diffraction study. Infrared spectroscopy and BET gas adsorption measurements. The peak area at the melting point from the various mixtures of nicotinic acid and CPG was increased with an increase of nicotinic acid concentration while the broad peak area was remained unchanged in the DTA curve. As shown in the powder X-ray diffraction patterns, the crystalline peaks of nicotinic acid disappeared in mixture with CPG, suggesting the interaction of nicotinic acid and porous powders. It was found that the larger the content of CPG, the higher the ratio of an amorphous state to a crystalline state. BET isotherm showed that as the amount of nicotinic acid was increased, the specific surface area was reduced proportionally to nicotinic acid content of up to 40% and remained constant thereafter. Sublimation of nicotinic acid from the mixture of nicotinic acid and CPG was examined. A large quantity of nicotinic acid was retained in the mixture when stored on various temperatures in vacuo for 10 hours. The nicotinic acid mixtures with CPG or GPG showed a high dissolution rates of nicotinic acid in aqueous solution, especially in the initial dissolution stage. CPG is expected to be a good pharmaceutical excipient to reduce the crystallinity of drugs and to prevent sublimation of drugs.
Effect of Polyisobutylene and Sealant Treatments on Ethylcellulose-Walled Methyldopa Microcapsules
신상철,고익배,Shin, Sang-Chul,Koh, Ik-Bae 한국약제학회 1989 Journal of Pharmaceutical Investigation Vol.19 No.1
For the prevention of the aggregation during microencapsulation, the effects and role of polyisobutylene(PIB), as a protective colloid, were studied. The effects of sealant treatment on the microencapsulation were studied. Methyldopa was microencapsulated with ethylcellulose (EC) by polymer deposition from cyclohexane by temperature change using PIB. The EC-microencapsulated methyldopa was sealed with spermaceti. The dissolution of methyldopa was influenced by the drug to wall ratio. When PIB was used, low aggregation of microcapsules occurred and the surface was smooth with a few pores. Treatment of microcapsules with spermaceti retarded the release of methyldopa, the release being affected by the percentage of sealant used and the particle size of the product.
신상철,고익배,Shin, Sang-Chul,Koh, Ik-Bae 한국약제학회 1991 Journal of Pharmaceutical Investigation Vol.21 No.4
Microencapsulation of sodium ascorbate with cellulose acetate phthalate(CAP) by coacervation/ phase separation method were carried out. Various factors affecting microencapsulation, i.e., surfactant concentration. CAP concentration, stirring speed and treatment of spermaceti as a sealing agent were studied. Dissolution rate. particle size distribution, surface feature and stability test were investigated. CAP microcapsules prepared using 0.5% span 80 as a surfactant showed smooth and round surfaces. The release of sodium ascorbate was retarded by microencapsulation with CAP and by sealant treatment with spermaceti. When triturated with sodium bicarbonate, CAP microcapsules were more stable than unencapsulated sodium ascorbate under various RH conditions at $37^{\circ}C$.
러시아 극동 마피야의 부산지역 수산물 유통관련 범죄활동에 관한 연구
신상철(Shin Sang cheol) 한국공안행정학회 2014 한국공안행정학회보 Vol.23 No.2
우리나라 주변의 국제범죄는 21세기형으로 급속히 진화하고 있다. 우리나라를 둘러싸고 있는 국제범죄조직으로 중국 흑사회, 홍콩ㆍ마카오의 삼합회, 일본 야쿠자, 러시아 마피야가 있다. 특히 러시아 극동 마피야는 연해주 및 사할린에 거주하는 교포 2세와 현지 마피야조직원들이 서로 연계하여 국내 연고자들을 통해 거점을 모색한 후 우리나라에 투자하거나 영주(F-5)비자를 취득하여 입국한 후 표면적으로는 수산업이나 해상 무역업에 종사한다고 하면서 실질적으로는 밀수나 마약을 통해 제2차 범죄를 일으키고 있어 우리나라가 극동 러시아와 중국 홍콩을 오가는 각종 범죄의 중간 경유지가 되고 있다. 이러한 국제범죄조직에 대한 대응방안의 일환으로, 국제적인 연계망을 구축하여 관련 국가와 더불어 국제협력방안을 모색하고, 인터폴과 아센안폴을 통해 범죄정보를 교환하며, 국제 사법 공조를 포함해 범죄인 인도 및 요구로 국제조약에 따라 해당 국가간 국제범죄조직 퇴치를 위한 활발한 교류와 유대강화가 요구된다. Organized crimes around Korea are rapidly evolving into those of the 21st-century style. For example, the Pseudo-Underworld Society Crime Organization of China, the Triad of Hongkong and Macao, the Yakuza of Japan and the Russian Mafiya of the Far East region are all transnational organized crime groups. Especially, the Russian crime group is making connections between 2nd-generation Korean residents in Primosky Kra and their local gangsters. Then they are using some of the Korean residents who have relatives in Korea to set up their base in the country. After that, they are entering Korea under the name of investment or with F-5 visas. Since then, they are superficially doing the fisheries or marine trade business, but actually committing secondary crimes such as smuggling and drug trafficking. Thus, Korea is becoming a passage of lots of crimes among the Far East region of Russia, China and Hongkong. As an effort to cope with the transnational crime organizations, it is needed to build up international networks through which affected countries cooperate with one another. In addition, those countries should make active exchanges and strengthen ties with one another to crack down on transnational organized crimes by sharing crime information through the INTERPOL and the ASEANPOL, establishing the international mutual criminal assistance system and reciprocally following international treaties providing anti-organized crime actions including extradition and repatriation.
신상철(Shin, Sang Chul),강인규(Kang, In Gyu),김진만(Kim, Jin Man) 한국콘크리트학회 2021 한국콘크리트학회 학술대회 논문집 Vol.33 No.2
본 연구에서는 탄소중립의 관점에서 전 세계적인 핵심 트렌드로 자리 잡은 포틀랜드 라임스톤 시멘트의 특성에 대한 문헌 고찰을 수행하였다. 석회석 미분말은 OPC 대비 탄소 배출량이 극히 적기 때문에 저탄소 혼합시멘트의 대표적인 SCM으로 발전되어 왔으며, 석회석 미분말을 15%까지 사용하더라도 일반적인 포틀랜드 시멘트와 동등한 성능을 갖는다고 다수의 연구에서 보고하고 있다. This study was conducted to investigate the properties of portland limestone cement, which has become a global trend from the perspective of carbon neutrality. Limestone has been developed as a representative supplementary cementitious material of low-carbon blended cement since carbon emission of limestone is extremely low compared to ordinary portland cement. According to the literature review, a number of studies have reported that portland limestone cement mixed with limestone up to 15% of cement has the equivalent performance to that of typical portland cement.