http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Hirschsprung 병에서 Transanal One-Stage Pull-Through 술식의 단기 성적
손경모,김해영,Son, Gyung-Mo,Kim, Hae-Young 대한소아외과학회 2001 소아외과 Vol.7 No.2
The aim of this study was to evaluate the short-term outcomes of the trans anal one-stage pull-through procedure(TOP) in Hirschsprung's disease. Eight patients aged 3 weeks to 8 months with Hirschsprung's disease underwent this procedure. A rectal mucosectomy was performed from just proximal to dentate line to the level of peritoneal reflexion, where muscle layer was incised circumferentially. Rectosigmoid was mobilized out through the anus, and full-thickness frozen biopsy was taken for confirmation of ganglionic cells. After the rectal muscular cuff was divided longitudinally in the posterior aspect, aganglionic bowel was removed and ganglionic colon was anastomozed to the anus. The mean operating time was 161 minutes, and the mean hospital stay after operation was 3.8 days. Five patients had three to four bowel movement per day without other therapy at mean postoperative 39.2 days. Although long-term follow-up will be required, the TOP might be the new alternative surgical procedure for Hirschsprung's disease.
대장암 환자의 혈장 carcinoembryonic antigen (CEA)와 세포내 CEA 염색패턴의 상관관계와 예후 분석
최동환(Dong Hwan Choi),신동훈(Dong Hoon Shin),박병수(Byung Soo Park),손경모(Gyung Mo Son) 대한종양외과학회 2015 Korean Journal of Clinical Oncology Vol.11 No.2
Purpose: The aim of this study was to investigate the prognostic factor for elevating serum carcinoembryonic antigen (CEA) in patients with colorectal cancer and to identify clinical usefulness of tissue CEA. Methods: Two hundred and eighty-five patients with colorectal cancer were performed serum CEA tests before and after surgery. Also resected tumors were checked expressions pattern of tissue CEA. Clinicopathologic factors were classified according to patient factors, tumor factors and molecular factors. Patient factors included age, sex, underlying liver disease, smoking history and other cancer history. Tumor factors included tumor size, intestinal obstruction, pathologic T status, lymph node metastasis, tumor differentiation, lymphatic invasion, vascular invasion, perineural invasion. Results: Serum CEA level was markedly elevated in the cytoplasmic pattern of tissue CEA compared to membranous pattern of tissue CEA. As cancer stage progressed, serum CEA level was elevated, which was confined to cytoplasmic pattern of tissue CEA. Independent factors for the elevation of serum CEA by multivariate analysis included tumor size (≥5 cm) (P=0.042), complete intestinal Obstruction (P=0.023) and serum CA 19-9 (≥37 U/mL) (P=0.027). p53 overexpression (≥10%) was related to cytoplasmic pattern in tissue CEA (P=0.005). Conclusion: The tumor size and bowel obstruction are considered the main factors, which cause the leakage of intracellular CEA. And membranous patterns of tissue CEA can be used in Stage I colorectal cancer patients, as an indicator for early prognosis and recurrence. However, more studies of colorectal population are required for further evaluation.