http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
고용량 스테로이드 치료 저항성 폐출혈 루푸스 환자에서 Rituximab 사용
임상우 ( Sang Woo Yim ),변창규 ( Chang Kyoo Byon ),박준용 ( Jun Yong Park ),이상엽 ( Sang Yeob Lee ),이성원 ( Sung Won Lee ),정원태 ( Won Tae Chung ) 대한류마티스학회 2014 대한류마티스학회지 Vol.21 No.4
Rituximab is a chimeric murine-human monoclonal antibody that is directed against the specific B-cell CD20 antigen, which has recently been successfully used in active or refractory systemic lupus erythematosus (SLE) manifestations, such as nephritis, thrombocytopenia, and vasculitis. We report a case of a 25-year-old woman diagnosed with diffuse alveolar hemorrhage of SLE refractory to steroid pulse therapy. The patient was treated successfully with rituximab as a part of the immunosuppressive regimen.
성경험이 없는 전신홍반루푸스 환자에서 발생된 뾰족 콘딜로마
김용준 ( Yong Jun Kim ),변창규 ( Chang Kyoo Byon ),김은석 ( Eun Seok Kim ),김현정 ( Hyun Jeong Kim ),정일환 ( Il Hwan Jeong ),안원석 ( Won Suk An ),이상엽 ( Sang Yeob Lee ),이성원 ( Sung Won Lee ),정원태 ( Won Tae Chung ) 대한류마티스학회 2014 대한류마티스학회지 Vol.21 No.2
Anogenital infection with human papillomavirus (HPV) is one of the most common sexually transmitted infections worldwide. The majority of HPV infections are transient and subclinical, with subsequent clearance by the immune system. However, in some individuals, especially those with impaired immunity, HPV infection may persist and result in condyloma acuminatum, pre-cancerous cervical abnormalities, as well as cervical cancer. Because of the intrinsic immunological aberrations and immunosuppressive treatment, patients with systemic lupus erythematosus (SLE) have higher prevalence of anogenital HPV infection, and SLE itself appears to be a major risk factor for HPV infection. HPV infection is sexually transmitted via genital contact; autogenesis of condyloma acuminatum without sexual contact is rare. In this case, a 27-year old virgin female with SLE was admitted to our clinic, presenting anogenital condyloma acuminata. It report that SLE patient can have a disease of anogenital HPV infection, despite the lack of sexual contact. Therefore, we recommend that patients with SLE have regular gynecological evaluations, in addition to prophylactic HPV vaccinations.
정진규 ( Jin Kyu Jung ),김용준 ( Yong Jun Kim ),변창규 ( Chang Kyoo Byon ),이상엽 ( Sang Yeob Lee ),이성원 ( Sung Won Lee ),정원태 ( Won Tae Chung ) 대한류마티스학회 2012 대한류마티스학회지 Vol.19 No.2
Adult onset Still`s disease (AOSD) is a systemic inflammatory disorder of unknown etiology. AOSD is characterized by fever, arthralgia, salmon-colored skin rash, hepatosplenomegaly and its laboratory abnormalities include leukocytosis, elevated liver enzyme, negative autoantibody, and hyperferritinemia. The clinical course varied and severe complicated conditions, such as hemophagocytic syndrome, and disseminated intravascular coagulation, occurred occasionally. Such a complication is accompanied with hemolytic anemia and lead to be a fatal course. We report the first case of AOSD with hemolytic anemia, which improved with high dose steroid therapy.