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      • SCOPUSKCI등재

        글루타치온 고함유 정미성 효모추출물 개발

        배인영(In Young Bae),구승현(Seung Hyun Koo),유현재(Hyun Jae Yoo),김종민(Jong-Min Kim),배현아(Hyun-Ah Bae),전은정(Eun-Jung Jeon),오언(Eon Oh),이대희(Dae-Hee Lee),허병석(Byung-Serk Hur),이현규(Hyeon Gyu Lee) 한국식품과학회 2010 한국식품과학회지 Vol.42 No.5

        본 연구에서는 다양한 효모 배양액을 자가소화 시킨 후 관능 검사를 통해 1차적으로 8종(S. cerevisiae 3종, C. utilis 4종 및 Z. rouxii 1종)을 선별하였다. 이 중 정미성과 균체 성장율을 고려하여 C. utilis인 SEM-Y8을 선정하여 고글루타치온 생산을 위한 균주 개량을 수행하였다. 두 번의 UV 처리를 통해 SEM-Y8보다 글루타치온 생성능이 2.0배 증가된 SY8-M2-1 개량 효모 균주를 얻었으며, 선택배지(4.0% yeast extract, 1.5% glucose, 0.04% NH<SUB>4</SUB>H<SUB>2</SUB>PO<SUB>4</SUB>, 0.04% L-cystein)를 사용함으로써 글루타치온 함량을 1.5배 더 향상시킬 수 있었다. 이상의 조건에서 얻어진 고글루타치온 함유 효모추출물은 마늘과 양파엑기스보다 우수한 감칠맛과 부드럽고 깊은 맛을 나타내었으며, SEM-Y8 대비 3.2배 향상된 라디컬 소거능을 나타내었다. Yeast strains with good sensory properties were selected, and those yeasts were subjected to mutation to develop high glutathione producing yeasts. In addition, the antiradical activity and flavoring effect of the yeast extract were evaluated. A total of 68 strains were screened, and three strains of Saccharomyces utilis, four strains of Candida utilis, and one strain of Zygosaccharomyces rouxii were selected based on the flavoring effect. Among them, a random mutation was elicited against SEM-Y8, resulting in a high flavoring effect and growth rate. The glutathione production by SEMY8 increased 2.0-fold following the mutation, and the DPPH radical quenching effect of the SY8-M2-1-derived extract increased 3.2-fold compared to that of the wild type. The sensory properties of the SY8-M2-1-derived extract were better than those of garlic or onion extract in umami and mouthfulness. Thus, the SY8-M2-1 extract could be used as a functional flavoring material with improved antiradical activity.

      • KCI등재

        연구논문 : 임종기 진료결정과 관련된 윤리적 문제에 대한 내러티브 분석: 말기 암환자들을 대상으로

        권복규 ( Ivo Kwon ),배현아 ( Hyun Ah Bae ) 한국의료윤리학회 2011 한국의료윤리학회지 Vol.14 No.2

        In order to understand fully the issues involved in end-of-life care decisions, it is important to know the genuine wishes and thoughts of terminal patients themselves. This article reports on a narrative analysis of the data drawn from structured interviews with a number of terminal patients suffering from critical diseases such as cancer. Most patients approve of the withdrawal of life support treatment in irreversible and extremely painful conditions. They also admit the necessity of "advance directives" and even active euthanasia. However, their attitudes toward disease and death are emotionally complex. In facing their own death, patients need more emotional/medical support and pain control. Their relationships with family members or friends are also critical in this regard. Terminal patients are not entirely satisfied with current methods of communication with care givers, although they appreciate their concerns and goodwill. This analysis concludes that it is necessary to approach end-of-life care decisions in a more subtle and humane way that should be customized to the demand of each individual patient these decisions should be treated as part of the overall medical care given to terminal patients.

      • KCI등재

        성희롱 피해자 보호를 위한 법적 조치 강화 방안 -건강권 보장 관점의 적용-

        권문영 ( Kwon Mun-nyoung ),강민아 ( Kang Min-ah ),배현아 ( Bae Hyun-a ) 제주대학교 법과정책연구원 2016 法과 政策 Vol.22 No.2

        This study examines issues, heretofore neglected, which have negative impacts on the health of victims of sexual harassment in South Korea. We review the current status of legal and institutional measures inteded to support victims in their recovery from sexual harassment, as well as the available assistance in he form of financial compensation. At the outset, in order to bring about increased attention to this issue, this study reviews current South Korean legal provisions, observes the extent to which these provisions actually overlook damage to victims’ health, and furthermore, how current practices aggravate damages to the victims. Next, after reviewing the European Union’s measures, as upheld by its member states, for the prevention of sexual harassment, the protection of its victims when it does occur, and corroborating regulatory health reports, this study lays out its proposed recommendations for the South Korean system. As for the improvements of measures to protect the victims of sexual harassment, first there needs to be a legal effort to define sexual harassment as a sub-category of harassment. Damage caused by the sexual harassment not only consists of mental and physical health violation but also additional damage caused by the act of bystanders and bullies blaming the victim rather than the perpetrator. Also the incident evokes violation of victim’s labor rights and their rights to learn where their lives become unstable. However, currently, Korea lacks a legal basis to protect such extensive damage of the victims. Therefore, by providing a legal basis for regulating the harassment is very effective in guaranteeing the right to health in a reactive approach to health damage caused by sexual harassment and a proactive preventive measure to ensure a safe living environment. Second, is to introduce the ancillary health system such as providing a therapeutic consultation and a leave system. In the case of sexual harassment, the moment when the violation happens, it causes both mental and physical health damage and there is a high chance of additional damage that can be caused by the community members where the victim resides. Thus providing a therapeutic consultation with the expert, separating victim and offender, and if the victim wishes, keeping the victim away from the community where the sexual harassment occurred is a way which can minimize other various damages. Thirdly, there is a need for expanding the criteria of injury in an industrial accident as a psychological trauma and comprehensively expanding the range of subject to vocational trainees, people who have applied for the position and employees whose contract has been terminated. Lastly, there is a need to actively raise issues about the structure of hierarchical gender system which perpetrates sexual harassment in Korea to create a healthy living environment where it could prevent the occurrence of sexual harassment.

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