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급성 약물중독에 합병된 일과성 혹은 지속성 고암모니아혈증의 특성
이수형 ( Soo Hyung Lee ),박홍인 ( Hong In Park ),최마이클승필 ( Michael Sung Pil Choe ),제동욱 ( Dong Wook Je ),노우영 ( Woo Young Nho ),김성훈 ( Seong Hun Kim ),이미진 ( Mi Jin Lee ),안재윤 ( Jae Yun Ahn ),문성배 ( Sung Bae Moon 대한임상독성학회 2016 대한임상독성학회지 Vol.14 No.2
Purpose: In patients with altered mentality caused by drugs or unknown causes, ammonia is checked to facilitate differential diagnosis or diagnose hepatic coma. This helps early prevention and treatment of brain damage due to hyperammonemia. This study was conducted to evaluate clinical characteristics of intoxicated adult patients with hyperammonemia. Methods: We evaluated 95 patients with hyperammonemia among intoxicated patients above the age of 15 who visited our ED from January 2013 to December 2015. We analyzed the demographic characteristics and type of poisoning substance, reason for ingestion, toxicological characteristics such as elapsed time from ingestion to hospital visit, lab, clinical progression and complications. Data were evaluated using the student`s t test or Mann-Whitney U test for continuous variables, and Chi-square test and Fisher`s exact test for frequency analysis of categorical variables. Results: When compared to healthy individuals, patients with hyperammonemia showed statistical significance on their SOFA score (p=0.016) and poison severity score (p<0.001). Additionally, patients with hyperammonemia showed significantly different initial serum AST level (p=0.012) and maximum serum AST level during the hospital stay (p=0.026) when compared to healthy individuals. Moreover, individuals with sustained hyperammonemia compared to transient hyperammonemia showed clinically significant SOFA scores (p<0.001), poison severity scores (p=0.007), mortality rates in the ICU (p=0.021), as well as different duration of hospital stay (p=0.037), serum creatinine level (p=0.002), erythrocyte sedimentation rate (p=0.025), and serum myoglobin (p=0.015). Conclusion: Most poisoning-induced hyperammonemia cases were transient and recovered without special treatment. Therefore, hyperammonemia is almost non-specific among poisoning patients.
직류 전원 분할용 커패시터의 용량변화가 복공진형 고주파 인버터의 특성에 미치는 영향
원재선(Jae-Sun Won),박홍일(Hong-Il Park),이경호(Kyung-Ho Lee),조규판(Gyu-Pan Cho),김동희(Dong-Hee Kim) 전력전자학회 2000 전력전자학술대회 논문집 Vol.2000 No.11
A half bridge type double resonant high frequency resonant inverter using PFM is described. This proposed inverter can reduce distribution of the switching current because of using the current of the serial resonant circuit to the input current of the parallel one. In the case of variable capacitance of the DC voltage source separated capacitor, the analysis of inverter circuit has generally described by using normalized parameter and operating characteristics has been evaluated in terms of switching frequency and parameters. Based on the characteristics value, a method of the circuit design is proposed. The theoretical results are in good agreement with the experimental ones. In the future, this proposed circuit is considerated to be useful for induction heating and discharge lamp.