http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
승모판막협착증의 평가방법으로서의 연속파 Doppler 심초음파도와 심도자법의 비교연구
김승관(S . G . Kim),박옥규(O . K . Park),강정채(J . C . Kang),박종춘(J . C . Park),정명호(M . H . Jeong),양승진(S . J . Yang),신순철(S . C . Shin),박상진(S . J . Park) 대한내과학회 1987 대한내과학회지 Vol.33 No.3
N/A In order to evaluate the feasibility of the noninvasive continuous wave Doppler (CWD) echocardiographic technique in evaluating transmitral pressure gradient and the effective mitral valve area, the 17 patients with pure or dominant mitral stenosis were examined by CWD echocardiography and by cardiac catheterization technique. By CWD technique mean and peak transmitral pressure gradient were measured as 9.5±4.0 mmHg, 13.9±4.9mrnHg respectively, and the effective mitral valve area was calculated as 0.62±0.16 cm², while by standard fluid filled catheter system the mean diastolic pressure gradient between the pulmonary capillary wedge position and the left ventricle was measured as 12.2±4.1mmHg, and effective mitral valve area by Gorlin and Gorlin formula was calculated as 0.66±0,39 cm. Each of the mean and peak diastolic pressure gradient by CWD was significantly correlated with the pressure gradient measured by cardiac catheterization technique (r=0.61, r=0,55, p<0.05, p<0.05, repectively). Effective mitral orifice areas measured by either of the technique were well correlated (r=0.73, p<0.02). We concluded that noninvasive CWD technique could be an alternative method to the cardiac catheterization in quantitating the severity of mitral stenosis.
원발성 간암에 있어서 혈청 Alphafetoprotein 의 진단적 의의에 관하여
박종춘(Jong Chun Park),김세종(S.J. Kim) 대한소화기학회 1984 대한소화기학회지 Vol.16 No.1
N/A An elevated serum alphafetoprotein (AFP) concentration in a nonpregnant adult is the most discriminating laboratory test indicative of malignant disease now available. AFP is found on low concentration in the serum of normal adults, but it appears in high concentration in fetal serum at 12 weeks gestation. Elevations in adults are associated with pregnancy, a variety of nonneoplastic liver diseases, primary hepatocellular carcinoma and teratocarcinoma containing yolk sac elements. Extensive evaluation of the serum AFP concentration as a diagnostic marker for primary hepatocellular carcinoma has been carried out over the last 10 years. The measurement of serum AFP concentration is very useful in the diagnosis of hepatocellular carcinoma. Hepatitis B virus has been linked to hepatocarcinogenesis and recent evidence suggests incorporation of the hepatitis B virus genome into the cancer cell chromosome. Serum AFP was measured quantitatively by radioimmunoassay technique in 296 patients, who visited the out-clinic or were hospitalized at Chonnam University Hospital during the period from June 1981 to July 1983. Those who were tested included 33 cases of normal population as control group, 133, hepatic diseases(46, primary hepatocelluar carcinoma; 11, hepatic metastatic tumor; 76, cirrhosis of liver; 13, acute viral hepatitis; 24, chronic hepatitis), 70 cases of nonhepatic malignant diseases, and 23 cases of the other nonhepatic diseases as the disease group. HBsAg was measured by enzyme immunoassay technique in 35 out of 46 cases of primary hepatocellular carcinoma. The results obtained were as follows; 1) The serum AFP concentration in 33 cases of normal control subjects was 4+-3 ng/ml (Mean+-S.D., Range: 0-12 ng/ml). Upper limit of serum AFP concentration in the normal adult was considered 10 ng/ml, which was derived from mean+-1.96 S.D. 2) In hepatic diseases, the serum AFP concentration was 30+-67 ng/ml(2-248 ng/ml) in acute viral hepatitis, 34+-57 ng/ml(1-260 ng/ml) in chronic active hepatitis, 10+-17 ng/ml (1-35 ng/ml) in chronic persistent hepatitis, 46+-74 ng/ml(0-350 ng/ml) in cirrhosis, 1,590+-2,245 ng/ml(0-8,000 ng/ml) in primary hepatocellular carcinoma and 86+-132 ng/ml(0-360ng/ml) in metastatic tumor of the liver. 3) Serum AFP concentration was exceeded the 400ng/ml only in hepatocellular carcinoma, which was revealed in 26 cases out of 46 cases of primary hepatocellular carcinoma. 4) HBsAg was positive in 21 cases out of 35 cases of primary hepatocellular carcinoma. In 16 out of 21 HBsAg positive cases, AFP was exceeded 400 ng/ml. 5) There were no significant changes of serum AFP concentration in the process of disease. Follow-up examination had been done at 2 to 6 weeks later the initial examination.