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이영진 ( Y. J. Lee ),이성건 ( S. K. Lee ),문병욱 ( B. U. Moon ),구진일 ( J. I. Koo ),김춘택 ( C. T. Kim ) 대한내과학회 1971 대한내과학회지 Vol.14 No.4
C.S.F. plays an important dignostic role in various diseases and in some infectious brain diseases, itprovides clues to definite diagnosis. The authors have experienced 27 hypertensive cases with 7 cases of control group and have obtained the following sta
Ethanol 이 가토 대뇌피질 Na-K-ATPase 활성에 미치는 효소역학적 분석
김주헌,문병욱 경상대학교 축산진흥연구소 1985 畜産振興硏究所報 Vol.12 No.1
Effects of ethanol on Na-K-ATPase activity were investigated with cerebral cortex homogenate in rabbit. The results were summarized as follows: 1. Na-K-ATPase activity was inhibited with dose-dependent manner by ethanol of higher concentration than 1% and showed an estimated I_(50)(the inhibitor concentration to cause 50% inhibition) of 3.5%. 2. Hydrolysis of ATP was linear with the incubation time in the absence and presence of 4j ethanol. 3. Inhibition of Na-K-ATPase activity by ethanol was not affected by increased enzyme concentration, and showed the reversibility of the inhibitory pattern. 4. Kinetic studies of cationic-substrate activation of Na-K-ATPase showed that ethanol had properties of classical competitive inhibition for K and non-competitive inhibition for Na and ATP.