http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
흰쥐에서 Cimetidine 투여가 알코올 대사에 미치는 영향
김재왕(Jae Wang Kim),정준모(Joon Mo Chung),최용환(Yong Hwan Choi),곽규식(Kyu Sik Kwak),권영오(Young Oh Kweon),김호각(Ho Gack Kim) 대한내과학회 1987 대한내과학회지 Vol.33 No.3
N/A For a study of the effects of cimetidine on ethanol metabolism, administered ethanol to male Sprague Dowley rats 1) 3 gm/kg per orally, 2) 1 gm/kg intraperitoneally and 3) 7 gm/kg intraperitoneally in each group, and checked serum ethanol concentration and ethanol concentration time curve, One week later, pretreated 120 mg/kg of cimetidine intraperitoneally and, 30 minutes later, administered ethanol to the same rets of each groups and also performed above described examination. The results obtained were as followed, The peak serum ethanol concentration (178.0±41.9 vs. 159.2±40.6mg%, P<0.05) and the area under serum ethanol concentration time curve (1013.2±364.8 vs. 755.4±257.3mg%hr, P<0.02) were significantly increased when cimetidine was introduced in the group with single oral dose of ethanol (3 gm/kg) and also when ethanol (1.0 gm/kg) was administered intraperitoneally, cimetidine produced a significant increase in the peak serum ethanol concentration (91.0±7.5 vs, 79.6±10.8mg%, P<0.05) and the area under sercum ethanol concentration time curve (142.5±185.5 vs. 104.4±20.0mg%hr, P<0.001). Serum ethanol elimination rate (105.5±10.4 vs. 151.7v21.3 mg% kg-1 hr-1, P<0.05) was much decreased in those had cimetidine pretreatment and ethanol administration per orally (7 gm/kg), especially at high ethanol concentration those are above 140 mg%. These results suggest that cimetidine should be prescribed with caution in alcoholics with upper gastrointestinal tract trouble.
원발성 간암에서 간동맥색전술 전후의 담낭의 초음파 검사상 변화
정준모(Joon Mo Chung),최용환(Yong Hwan Choi),김재왕(Jae Wang Kim),김호각(Ho Gack Kim),권영오(Young Oh Kweon),곽규식(Kyu Sik Kwak) 대한소화기학회 1987 대한소화기학회지 Vol.19 No.1
N/A Transcatheter arterial embolization (TAE) is, now, one of the established treatment for hepatocellular carcinoma. We compared serial echographic changes of gallbladder after TAE with clinical symptoms in 7 cases of hepatoma. The results obtained were as follows: 1) Sonographic findings of acute cholecystitis such as gallbladder wall thickening, subserosal sonolucent halo and gallbladder distension were noted in 4 cases. One out of 4 cases, there noted intraluminal membrane. 2) The patients who complain of severe abdominal pain disclosed somewhat sonographic changes of gallblaader after TAE and also in whom had been TAE through common hepatic artery or rt hepatic artery. These findings suggest that ischemic cholecystitis by cystic artery emlolization during TAE in one of major causes of severe abdominal pain.
간경변증에서 특발성 세균성 복마염 증상을 가진 환자중 복수의 균 배양이 양상이 자와 음성인 자의 비교
정준모 ( Joon Mo Chung ),최용환 ( Yong Hwan Choi ),권영오 ( Young Oh Kweon ),김재왕 ( Jae Wang Kim ),곽규식 ( Kyu Sik Kwak ),김호각 ( Ho Gack Kim ) 대한소화기학회 1987 대한소화기학회지 Vol.19 No.1
N/A A retrospective study was done for evaluation of any differences in clinical features and prognosis between cirrhosis patients having symptoms of spontaneous bacterial peritonitis with culture positive ascites and those having symptoms with culture negative ascites. All the patients had been suffering from liver cirrhosis with spontaneous bacterial peritionitis clinically, whose ascites containing more than 250/mm3 in polymorphonuclear leukocyte count. There were no differences between both patients in biochemical analysis of serum and ascites, cell count of WBC and polymorphonuclear leukocyte of ascites, clinical features and mortality rate. Therefore it is suggested that the patient having symptoms of spontaneous bacterial peritonitis, even if culture negative ascites, should be treated carefully with early antibiotic therapy and positive attitude.