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박준용(Joon Yong Park),한동수(Dong Soo Han),윤병철(Byung Chul Yoon),이오영(Oh Young Lee),손주현(Joo Hun Sohn),함준수(Joon Soo Hahm),박경근(Kyung Geun Park),김정현(Jeogn Hyun Kim),이민호(Min Ho Lee),기춘석(Choon Suhk Kee),박경남(Kyung 대한소화기학회 1995 대한소화기학회지 Vol.27 No.4
N/A Background/Aims: Diabetes mellitus is thought to be a risk factor for gallstone diseases, esopecially cholesterol stone. The risk of cholelithiasis among diabetic persons cou]d be due to several mechanisms, including impaired gallbladder motility and hyperinsulinemia. We investigated the relationship of gallstones in the diabetic patients and analyzed their clinical course and related factors. Methods: A collective review of ] 1,302 diabetic patients from January l979 to December 1993 were carried out at Hanyang University Hospital. Of the 323 cases with gallstones, 180 cases were evaluated for age, body mass index, duration of disease, HbAlc, fasting blood sugar, AST/ALT, cholesterol level and triglyceride level. Results: The prevalence of gallstones in the diabetics studied was 2.86%. The composition of gallstones was not related to age, and pigmented stones were most commonly observed. The incidence c>f cholecystectomy was 0.27% in men, and 0.47% in women. Conclusions: The prevalence of gallstones in diabetic patients was higher than in the normal population, which could be explained by the decreased mcotility of the gallbladder or obesity. No significant difference was found in age, body mass index, cholesterol level, and triglyceride level when compared to patients with or without gallstones. (Korean J Gastroenterol 1995;27:433 - 440)