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      • KCI등재

        복합 해양치유 프로그램이 대사성 질환자의 혈중지질 및 CRP에 미치는 영향

        김의식 ( Ui-sik Kim ),현준 ( Hyun-jun Kim ),신재숙 ( Jae-suk Shin ) 대한통합의학회 2021 대한통합의학회지 Vol.9 No.4

        Purpose : The purpose of this study is to verify the effectiveness of combined marine healing programs by analyzing the physical composition of metabolic patients, blood lipids and the effects of the inflammatory factors, the C -reactive protein(CRP). Methods : the combined marine treatment program was conducted for 6 hours a day, 5 days a week on the 10 adult patients with metabolic diseases and the results of their body composition, blood lipids and CRP were analyzed before and after the subjects completed the program. For the statistical analysis, the mean and standard deviation (M±SD) of each variable were calculated using SPSS version 20 and a paired t-test was conducted in order to test for the differences before and after the combined marine treatment program. All significant levels were set to α=.05. As a result of the experiment Results : First, regarding the changes in body composition and blood pressure after the 5-day combined marine treatment program was completed, there were statistically significant differences found in weight (p<.01) and systolic blood pressure (p<.05). Second, regarding the changes in blood lipids and CRP after the program was conducted, there were statistically significant differences found in total cholesterol (p<.05) while there was no statistically significant difference found in the variables of neutral fat, low-density lipoprotein cholesterol and CRP. Conclusion : the study results were integrated, the 5-day combined marine treatment program had a positive effect on weight, blood pressure and total cholesterol in the patients with metabolic diseases. Therefore, the short-term marine treatment program was thought to be effective for them. However, considering no significant differences were found in neutral fat, low-density lipoprotein cholesterol and CRP, further development and research on combined marine treatment programs should be conducted in the long term to create an effective program for patients with metabolic diseases.

      • 근위 대퇴골에 발생한 전이성 골종양의 병적 골절의 수술적 치료: 종양대치 인공관절 치환술과 골절 고정술의 치료 성적 비교

        신덕섭,김의식,곽해준,고영진,Shin, Duk-Seop,Kim, Ui-Sik,Kwak, Hae-Jun,Ko, Young-Jin 대한근골격종양학회 2011 대한골관절종양학회지 Vol.17 No.1

        목적: 근위 대퇴골에 발생한 전이성 골종양의 병적 골절 혹은 임박 골절의 수술적 치료방법 중 광범위 절제술 후 종양대치 인공관절 치환술과 골절의 정복 후 골수강정을 이용한 고정술의 치료 성적을 비교하는데 있다. 대상 및 방법: 1994년 5월에서 2009년 5월까지 근위 대퇴골 전이성 골종양으로 인한 임박골절 및 병적골절로 본원에서 수술한 37명(38예))을 종양대치 인공관절 치환술을 시행한 군(1군; 22명)과 골유합 고정술을 시행한 군(2군; 15명, 16예)으로 나누었다. 평균 연령은 1군은 59세, 2군은 60세였으며, 평균 추시 기간은 수술 후 1군은 23개월, 2군은 11개월이었다. 두 수술군의 치료성적은 종양학적 성적과 Musculoskeletal Tumor Society (MSTS) scoring system, 1993의 기능적 평가방법, Kaplan-Meier 생존분석을 시행하였으며, 통계학적 분석은 Log rank test, T-test를 이용하여 평가하였다. 결과: 수술 후 평균 생존기간은 1군은 24개월(3-110개월), 2군은 11개월(1-33개월)이었으며, 1년 생존율은 1군은 86% (19/22명), 2군은 50% (8/16명), 2년 생존율은 1군은 30% (5/22명), 2군은 9% (1/16명)였다. MSTS scoring system, 1993의 기능적 평가방법을 이용한 종합적인 성적에서 1군은 평균 26점(19-30점), 88%, 2군은 평균 15점(10-23점), 51%로 평가되었다. 결론: 근위 대퇴골에 발생한 전이성 골종양의 치료 방법 중 선택된 환자에서 실시한 광범위 절제술 후 종양대치 인공관절 치환술은 골절 고정술 보다 종양학적 성적 및 기능적 성적이 우수한 것으로 나타났다. Purpose: To compare clinical outcomes of the tumor prosthetic replacement and osteosynthetic fixation for pathologic fracture of skeletal metastatic lesion of the proximal femur. Materials and Methods: From 1994 May to 2009 May, medical records of 22 patients who underwent tumor prosthetic replacement with tumor resection (group 1) and 15 others (16 hips) who underwent osteosynthetic fixation without tumor resection (group 2) were reviewed. The mean age of overall patients were 59 (group 1) and 60 (group 2). Mean follow up periods were 23 and 11 months. The oncological and functional results were evaluated with Kaplan-Meier methods and Musculoskeletal Tumor Society (MSTS) scoring system, 1993. The statistical evaluation was assessed with Log rank test and t-test. Results: The mean survival periods were 24 months in group 1 and 11months in group 2. The 1 year survival rates were 86% in group 1 and 50 % in group 2, and 2 year survival rates were 29.7% in group 1 and 9.4% in group 2. The mean MSTS functional score were 26.4 (19-30), 87.9% in group 1 and 15.3 (10-23), 51.0% in group 2. Conclusion: The results of tumor resection and prosthetic replacement in selected cases was better than osteosynthetic fixation without tumor resection for metastatic bone tumors around proximal femur in oncological and functional aspects.

      • 악성 흑색종의 치료결과 분석

        신덕섭,김의식,Shin, Duk-Seop,Kim, Ui-Sik 대한근골격종양학회 2011 대한골관절종양학회지 Vol.17 No.1

        목적: 악성 흑색종의 치료 결과를 분석하고 예후 인자에 대해 알아보고자 하였다. 대상 및 방법: 1996년 1월부터 2005년 12월까지 악성 흑색종으로 진단 받고 외과적 절제술 시행 후 추시가 가능하였던 31예를 대상으로 하였다. 평균 추시 기간은 46.5개월이었고 평균 연령은 56.9세였다. 나이, 성별, 발생 부위, 종양의 두께, 림프절 전이유무, 면역화학 요법의 시행 유무에 따른 5년 생존율을 비교하였다. 결과: 전체 환자의 5년 생존율은 80.6%였고 발병 연령이 65세 미만인 경우 5년 생존율은 89.7%였고 65세 이상에서는 66.7%였다. 남자의 5년 생존율은 75%였으며 여자는 90.9%였다. 발생 부위에 따라 상지에 발생한 경우 66.7%, 하지에 발생한 경우 89.5%, 기타 부위에 발생한 경우 66.7%의 5년 생존율을 보였다. Clark level IV 이상에서는 62.5%의 5년 생존율을 보였고 III 이하에서는 100% 였다. 림프절 전이가 있었던 경우 5년 생존율은 53.8% 였고, 없었던 경우는 100%였다. 결론: 악성 흑생종 치료에 있어 조기 발견 및 광범위 절제술이 가장 효과적인 치료 방법으로 생각되며, 예후 인자에 있어서 나이, Clark level, 림프절 전이가 통계적 유의성이 있는 것으로 나타났다. Purpose: This study was designed to evaluate the treatment results of malignant melanoma and to analyze the factors influencing prognosis. Materials and Methods: Thirty one cases of malignant melanoma were included in this study. They were treated in our hospital surgically, medically and immunologically from January 1996 to December 2005, and were followed more than 5 years. We compared 5 year survival rate (5YSR) according to the age, gender, anatomical site, depth of tumor, TNM stage, involvement of lymph node and immuno-chemotherapy. Results: Overall 5YSR was 80.6%. 5YSR of the age group below 65 years was 89.7% and 66.7% for the age group over 65 (p=0.033). 5YSR for men was 75% and 90.9% for women. 5YSR according to the site of occurrence showed 66.7% in upper extremities, 89.5% in lower extremities, and 66.7% in other site. 5YSR was 100% for the Clark level below III and 62.5% for the level above IV (p=0.032). 5YSR was 53.8% for lymph node metastasis group and 100% for non-lymph node metastasis group (p=0.021). Conclusion: We concluded that early diagnosis and wide excision was the most important in treatment of malignant melanoma. The prognostic fractors of malignant melanoma were age, depth of tumor (Clark's stage) and metastasis of lymph node.

      • 부반응 저감 조성 K계 건식 CO<sub>2</sub> 흡수제 특성평가

        장영신,김의식,윤양노,백점인,Jang, Young-shin,Kim, Ui-sik,Yoon, Yang-no,Baek, Jeom-In 한국전력공사 2019 KEPCO Journal on electric power and energy Vol.5 No.4

        In this study, the effects of two materials, active alumina and CaO based inorganic binder, which cause the side reaction on the K2CO3-based solid CO2 sorbents was investigated. K2CO3-based solid sorbents called KAM series was prepared by spray drying method and then measured its physical properties and CO2 sorption capacity. Among the KAM series sorbents, KAM(0.5) maintained high CO2 sorption capacity of 7.6 wt% after 3 cycle of sorption/regeneration reaction and showed very low attrition loss as low as 3.1 % which was measured by ASTM D5757-95.

      • SCOPUSKCI등재
      • IGCC 용 석탄가스화기의 유동특성에 관한 수치해석

        주지선(Ji-Sun Ju),김의식(Ui-Sik Kim),정재화(Jae-Hwa Jung),시문(Si-Moon Kim) 대한설비공학회 2011 대한설비공학회 학술발표대회논문집 Vol.2011 No.7

        Entrained flow gasifiers that may operate in an upflow or downflow manner widely used for coal gasification reactor in Intergrated Gasifiaction Combiend Cycle(IGCC) power plant. In this Study Computational Fluid Dynamics(CFD) simulation of commercial-scale entrained-flow gasifiers was conducted to study the inside flow behavier of entrained flow gasifiers. The numerical model used in this study is composed of Lagrangian particle tracking model, volatilization model, char gasification model, and gas phase reaction with Arrhenius rate kinetic reaction and solved by FLUENT. The numerical simulations with developed coal gasification model were performed on commercial-scale one-stage upflow and single-stage downflow gasifiers. Based on simulation results, the comparision of flow characteristics was investigated for the two different entrained flow gasifiers.

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