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- 저자 : 김명혜(Myoung Hae Kim) (검색결과 3 건)
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김낙두(Nak Doo Kim),한병훈(Byung Hoon Hahn),이은방(Eun Bang Lee),공재양(Jae Yang Kong),김명혜(Myoung Hae Kim),진창배(Chang Bae Jin) 한국생약학회 1979 생약학회지 Vol.10 No.2
Two pure saponin components, Panax saponin C (protopanaxatriol derivative, ginsenoside Re) and Panax saponin E (protopanaxadiol derivative, ginsenoside Rb_l) were isolated from Panax ginseng root and their acute toxicities in mice and antistress effects in rats were investigated. Average lethal doses (LD_(50)) of ginsenoside Re were 130㎎/㎏ (i.v.), more than 1,000㎎/㎏ (i.p.) and more than 1,500 ㎎/㎏ (s.c.), respectively. Average lethal dose of ginsenoside Rb₁ was 243㎎/㎏ intravenously. Adrenal ascorbic acid and cholesterol contents were significantly decreased when normal rats were exposed to heat (40℃) for 30 min. The reduction of the adrenal ascorbic acid and cholesterol contents in rats was partially prevented when the rats received the ginseng saponins prior to exposure to heat stress and most pronounced effects were observed in rats received ginsenoside Re. However, it was found that administration of ginseng alone, without stress, did not significantly change the ascorbic acid and cholesterol contents in adrenal glands. Eosinophil counts in the blood of the rats were elevated when the rats were exposed to the heat stress, and the elevation of the eosinophil counts were prevented with the ginseng saponins under the stress, but the changes were all insignificant statistically.
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건강신념모델을 적용한 AIDS예방의 건강신념, 태도 및 건강행동
김명혜 韓國保健敎育學會 1997 보건교육건강증진학회지 Vol.14 No.2
This study was conducted in order to identify the extent to which Health Belief Model(HBM) constructs explain the likelihood of taking preventive behaviors for AIDS among the young adolescents in Korea. HBM was applied as the theoretical framework for developing questionnaire items in this study. The survey instrument included all of the constructs of Health Belief Model, namely, perceived susceptibility, perceived severity, perceived benefit, perceived barriers, cue to actions for preventive behaviors concerning AIDS. Additionally, demographic characteristics of the respondents, their sexual experiences, and AIDS Knowledge Test were included in the study. Each of HBM constructs were developed with a 5-point Likert type scale from 1(never agree) to 5 (absolutely agree). The survey was conducted with a total of 247 military men in a city on September 18, 1996, using self-reported questionnaire. The results of the study were summarized as follows: 1. Because the subjects for this study were military soldiers, their demographic characteristics were limited to all men, young age, and unmarried. Educational status was evenly distributed between high school graduates and university students. 2. On the average, the respondents started their first sexual relationship at 18 years old and 82.6% of them did not use condom when having their first sexual experience. Thirty one percent of the subjects had sexual contact with prostitutes and the average number of sexual contact with prostitutes was 5 times during the past 2 years. 3. The results of AIDS Knowledge Test scores demonstrated that the respondents had a high level of knowledge about AIDS. However, some misconceptions about transmission of AIDS through casual contact were still prevailed. Sixty-six percent of the respondents expressed that people infected with HIV should be isolated from the society in order to protect the general public. 4. All the respondents expressed that they had heard about AIDS before. TV was found to be the source which provided information on AIDS most frequently. 5. Among fundamental constructs of Health Belief Model, scores of perceived benefit of taking preventive action against AIDS marked the highest score, while scores of perceived susceptibility were the lowest. As a result of Multiple Stepwise Regression analysis, 13 variable groups were found to predict the preventive action by 25%. Among them, only perceived benefit variables was the most significant factor to explain preventive behaviors by 17%.
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