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      • KCI등재

        升麻葛根湯加味方이 마우스의 抗 ALLERGY 및 免疫反應에 미치는 影響

        김남권,황충연,임규상,Kim, Nam-Kwen,Hwang, Chung-Yeon,Lim, Gyu-Sang 대한한방안이비인후피부과학회 1995 한방안이비인후피부과학회지 Vol.8 No.1

        Seungmagalgeuntang-gamibang has long been known to have anti-allergic effect. However, the mechanism of action of Seungmagalgeuntang-gamibang is not well investigated. The author analysed the effects of Seungmagalgeuntang-gamibang on the vascular permeability, delayed-type and contact hypersensitivities, and phagocytic function, the results obtained are as follows: 1. Administration of Seungmagalgeungtang-gamibang decreased the vascular permeability induced by serotonin in the mouse. 2. Administration of Seungmagalgeuntang-gamibang decreased the vascular permeability induced by histamine without statistical significant. 3. Administration of Seungmagalgeuntang-gamibang decreased the delayed-type hypersensitivity induced by sheep red blood cells. 4. Administration of Seungmagalgeungtang-gamibang decreased the contact hypersensitivity induced by dinitrochlorobenzene. 5. Seungmagalgeungtang-gamibang increased the phagocytic-activities of macrophages in vitro and in vivo. 6. Seungmagalgeungtang-gamibang enhanced the formation of reactive oxygen intermediates in vitro and in vivo. The above results demonstrate that Seungmagalgeuntang-gamibang suppresses the hypersensitivity reactions with increasing the phagocytic functions and formations of reactive oxygen intermediates from macrophages.

      • KCI등재

        외안근 전침요법을 이용한 교통사고 유발 마비성 사시 환자의 치험 1례

        김남권,Kim, Nam-Kuon 대한한방안이비인후피부과학회 2008 한방안이비인후피부과학회지 Vol.21 No.1

        Objectives : We already reported the effectiveness of this treatment method(electroacupuncture at oculomotor muscles) at the adult and young idiopathic paralytic strabismus patients and Miller-Fisher syndrome. Then I explored the possibility for improvement of the traumatic injury paralytic strabismus case. Methods : I treated the case by using the electroacupuncture at both paralytic lateral rectus muscle lesions. The case was treated almost daily and every treatment was enforced 10 minutes. I use the PG-306 electra-acupuncture products(Suzuki Iryoki Co. Japan) and apply the low consequence wave of 1-8Hz. Results : We gained good results from the case and not observed any sides effect or compliant. So I hope to apply this treatment for traumatic and post-operative nerve injury cases and am sure to make the treatment protocol for them in the future.

      • KCI등재후보

        2005년 심사평가원 질의를 근거한 향후 학회의 역할 고찰

        김남권,Kim, Nam-Kuon 대한한방안이비인후피부과학회 2006 한방안이비인후피부과학회지 Vol.19 No.3

        I reviewed some offical documents from Health Insurance Review Agency(HIRA) asked expert opinions of our society about some controversy between doctors and HIRA The results are as followed : 1. We must compensate the details of textbook about general treatment of frequent1y occurred disease. 2. We mush verify the obstinate disease and write papers consequently. 3. We must educate and use the special techniques of our societic area. 4. We must write papers about the recently developed intervention equipments.

      • KCI등재

        Global existence for 3D Navier-Stokes equations in a long periodic domain

        김남권,곽민규 대한수학회 2012 대한수학회지 Vol.49 No.2

        We consider the global existence of strong solutions of the 3D incompressible Navier-Stokes equations in a long periodic domain. We show by a simple argument that a strong solution exists globally in time when the initial velocity in H1 and the forcing function in Lp([0; T);L2),T > 0, 2 p +1 satisfy a certain condition. This condition commonly appears for the global existence in thin non-periodic domains. Larger and larger initial data and forcing functions satisfy this condition as the thickness of the domain ϵ tends to zero.

      • KCI등재

        龍膽瀉肝湯의 抗바이러스 活性 및 免疫反應에 對한 實驗的 考察

        김남권,김종한,임규상,황충연,Kim, Nam-Kwen,Kim, Jong-han,Lim, Gyu-sang,Hwang, Choong-yeon 대한한방안이비인후피부과학회 1998 한방안이비인후피부과학회지 Vol.11 No.1

        During the last few years, nitric oxide(NO) as a potent macrophage-derived effector molecule against a variety of bacteria, parasites, and tumors has received increasing attention. More recent studies suggest that NO also has antiviral effects in both murine and human cells. The objective of the current study was to determine the effect of Yongdamsagantang(YST) on the production of NO. Stimulation of mouse peritoneal macrophages with YST after the treatment of recombinant $interferon-{\gammer}(rlFN-{\gammer})$ resulted in the increased NO synthesis. YST had no effect on NO synthesis by itself. When YST was used in combination with $rIFN-{\gammer}$, there was a marked cooperative induction of NO synthesis in a dose-dependent manner. The optimal effect of YST on NO synthesis was shown 6 hour after treatment with $rIFN-{\gammer}$. This increase in NO synthesis was reflected as increased amount of inducible NO synthase(iNOS) protein. NO production was inhibited by $N^G-monomethyl-L-arginine$. The increased production of NO from $rIFN-{\gammer}$ plus YST-stimulated cells was decreased by the treatment with staurosporin. In addition, synergy between $rIFN-{\gammer}$ and YST was mainly dependent on YST-induced tumor necrosis $factor-{\alpha}(TNF-{\alpha})$ secretion. These results suggest that the capacity of YST to increase NO production from $rIFN-{\alpha}-primed$ mouse peritoneal macrophages is the result of YST-induced $TNF-{\alpha}$ secretion.

      • KCI등재

        乾癬에 對한 東.西醫 文獻的 硏究

        김남권,황충연,임규상,Kim, Nam-Kwen,Hwang, Chung-yeon,Lim, Gye-sang 대한한방안이비인후피부과학회 1999 한방안이비인후피부과학회지 Vol.12 No.1

        Psoriasis is the recurrent disease of skin and till now its mechanism, pathogenesis and treatment are not clearly discovered. So, like these papers, we must investigate more safety and effective treatment of psoriasis. And I obtained the following condusions from the Oriental and Occidental bibliographic investigation. 1. In Oriental medicine. Baikbi, Pungsun, Eunselbyong, Songpisun, Baikselpung were the other names of Psoriasis. 2. In Occidental medicine, genetic factors, aggravation and inducible factors, biochemical factors, immunologic factors, disorder of epidermal kinetics, vascular malformation of dermis were cosidered to the pathogenic factors of psoriasis. 3. In Oriental medicine, the pathogenic factors of psoriasis were divided two parts. One is exogenous pathogenic factors which including the blood-heat, blood dryness, blood stasis, deficiency of liver and kidney, inharmony of impulsive and appointed pulsation, deficiency of blood. The other is exogenous pathogenic factors which including the wind-evil, wind-wetness, wind-heat, wind-cold, wetness-heat, cold-wetness, heat-evil. 4. In Occidental medicine, external applicative medicine, internal medicine, ultraviolet therapy, ultraviolet - external applicative medicine compound therapy and etc. were used the therapy of psoriasis. 5. In Oriental medicine, clean away heat and cooling blood, aliment the blood and moisturize, activating blood and expelling blood stasis, harmonize and invigorate the liver and kidney, invigorate the kidney, aliment the blood and moisturize the skin, aliment the blood and expelling the wind, expelling the wind and wetness, clean away heat and expelling wind, expelling the wind and scatter the cold, clean away heat and expelling the wetness, heat up the meridian and scatter the cold, clean away heat and remove the toxin and etc. were used the method of internal therapy of psoriasis. 6. Until Qing dynasty, wind expelling effective prescriptions like Bangpungtongsungsan, Sopungsan. Supungsunkisan and etc. were used and recently Yanghyelgeupungtang, Hwalhyelgeupungtang, Samultanggagam and etc. were used the internal therapy of psoriasis. 7. In the external therapy of psoriasis, Yuhonggo, Pungyugo, Sekryupiyeongo were used the plaster therapy and Folium Rerillae, Camphora, Fructus, Xanthii, Herba Spirodelae compound prescription were used the cleansing therapy, Okgisan, Chiunsan, Galmyogo, Hobunsan, Muisan, Madugo, Jeyugohengin were used the rubbing skin therapy. Rangdok Radix Aconiti, Bijeonilchoalkwang were used the attaching therapy, the extract of Rhizoma Et Radix Veratri was used the spreading pouder therapy. 8. In the acupuncture therapy of psoriasis, the Jelgol, chok Samni(S36), Kansa(P5), Haegye(S41), Wijung(B40) and etc. were used the acupuncture point, and the angle of helix incision threapy that disinfect and cut the angle of helix and plaster the Semen Glycine and Squama Manitis were used.

      • KCI등재

        성인 만성 아토피 피부염 환자의 삶의 질과 한방 치료비용에 대한 고찰

        김남권,오용열,서은성,이동효,Kim, Nam-Kwen,Oh, Yong-Leol,Seo, Eun-Sung,Lee, Dong-Hyo 대한한방안이비인후피부과학회 2010 한방안이비인후피부과학회지 Vol.23 No.1

        Objective : The aim of this study is to assess the impact of chronic atopic dermatitis (AD) on quality of life (QoL) as well as the economic burden associated with oriental medical treatment on adult patients with chronic AD in Korea. Methods : The EQ-5D health states, existence and duration of AD in the 2007 National Health and Nutrition Examination Survey (NHANES) were used to obtain the study subjects. A questionnaire including the questions on direct medical and direct non-medical costs associated with oriental medical treatment for adult patients with AD was specifically designed. Twenty-nine, members of the Korean Oriental Medical Ophthalmology, Otolaryngology and Dermatology Society (KOMOODS), completed the questionnaires. Results : The incidence of AD was around 3.09% in 2007 NHANES (sample survey, n=2981). Three months and above in duration of disease was 1.35%. The QoL data revealed as follows: 0.932 in non-chronic AD, 0.916 in chronic AD, and 0.908 in non-AD. We also stratified our analysis by age. The QoL data in 40's was statistically significant (P<0.023). But, no significant differences were reported in 20's, 30's, and 50's. The total direct medical costs of oriental medical treatment for AD was about 2,560,717 Won, and total direct non-medical costs was about 605,125 Won in a year. Conclusions : This study might be applied to find the evidence of economic evaluation in oriental medicine for AD. More rigorous studies are warranted.

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