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金明惠,崔美德,崔江姬,孫仁子,金惠英 한국병원약사회 1985 병원약사회지 Vol.2 No.2
1.여러가지 용량 및 제형의 약품개발이 필요하다. 장기투약시 사용되는 약품들의 장기보관상의 문제점을 해소하고 투약대기 시간을 단축할 수 있다. 2.새로운 투약방법의 모색이 필요하다. 장기투약을 필요로 하는 질환의 경우 매법 거의 같은 내용의 처방을 여러가지 단계를 거쳐 발행받아야 하는 번거로움을 Refill system등의 시도로 해소가 가능하다. 3.환자의 경제적인 측면을 고려하여 결핵이외의 몇몇 장기투약 질환들의 보험적용기간의 확대가 필요하다.
李順實,宋世欽,張升銀,安成淑,兪映旭,潘美子,權五名,崔美德,劉胤淑,嚴基和,李內球,李民和 한국병원약사회 1989 병원약사회지 Vol.6 No.3
The present situation of the alternation of dosage forms in dispensing of oral drug products for pediatric patients in Seoul National Univ. Children's Hospital was studied. The total prescriptions in July 1988, were 16,058. The alternations were as follows: tablets and capsules intended for constitution as powders; tablets and powders as capsules; tablets and powders as tablets; tablets, powders and injection as liquids. The kinds of the oral drug products prescribed were 254, including 139 for alternation (57.4%). The total number of dispensing oral drugs was 17,692 and that of dispensing after alternation was 5,311 in it(29.6%). The alternations consisted of 56.5% for grinding tablets for constitution as powders, 16.3% for opening of capsules as powders. The most reason of alternation was that the absence of dosage form equal to the dose prescribed(61.0%). The highest frequency of alternation was showed in the department of thoracic surgery(77.8%) in outpatient's prescriptions and showed in neonate intensive care unit(45.6%) in inpatients'. On the basis of the results of this study, several problems caused by the alternation were discussed, such as changes in bioavailibility, loss in dose, stability and the problem of feeding. It was suggested that the information in alternation must be given by the pharmaceutical manufacturer and the hospital pharmacists must consider these problems in pediatric dispensing. Above all, it was more desirable to develope pediatric dosage forms by the pharmaceutical manufacturer.