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Burden of Healthcare Utilization Associated with Diabetes Mellitus in COVID-19 Infected Patients
( Md Azharuddin ),( Mohammad Adil ),( Upasna Gaba ),( Manju Sharma ) 대한결핵 및 호흡기학회 2021 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.129 No.-
Purpose There available evidences of increased incidence and severity of COVID-19 in patients with diabetes mellitus (DM) reported with higher risk for intensive care unit (ICU) admission and substantial mortality. We carried out a systematic literature review and meta-analytic synthesis to find out the association between diabetes mellitus (DM) and related healthcare utilization burden in patients with COVID-19 infection. Methods We systematically searched MEDLINE, and Web of Science to identify studies investigating resource utilization of diabetic patients exposed to COVID-19. Meta-analysis was carried out using Review Manager 5.3. The random effects model was used to compute the pooled estimates of odds ratio/mean difference (OR)/(MD) and 95% confidence intervals (CI). Results Results from the pooled meta-analysis found that significant association was found between mortality and DM vs. nondiabetic [OR (95% CI): 2.46 (1.68, 3.58)]. ICU admission and use of mechanical ventilation were significantly associated with DM and COVID-19 vs. non-diabetic [OR (95% CI): 2.79 (1.79,4.34) and 3.33 (2.05, 5.42)], respectively. However, LOS, hospitalization, and ICU admission were not significantly different between patients with DM vs. non-DM. Conclusion The Results showed a significant association between mortality and DM exposed with COVID-19. Other co-morbidities especially CVD/hypertension could be a serious threat for DM COVID-19 infected patients for the higher mortality.
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