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RISS 인기검색어
- 검색키워드
- 저자 : ( Sujan Gautam ) (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
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Review of Series of 9 Cases of Hepatolithiasis Managed at Community-Based Hospital of Nepal
( Sujan Gautam ),( Narendra Pandit ),( Laligen Awale ),( Kunal Bikram Deo ),( Tek Narayan Yadav ),( Shailesha Dhikary ) 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1
Aims: Hepatolithiasis is a rare disease with high rate of treatment failure and recurrence. This study aims to review the management and outcome of hepatolithiasis from an endemic region. Methods: Retrospective review of prospectively maintained database of patients with hepatolithiasis managed surgically (2015- 2019) was performed. Diagnosis was based on the clinical findings and radiological investigation (CT/MRI). Demographic data, clinical presentation, extent of disease and operative procedure were evaluated. The outcome measures included immediate stone clearance, postoperative complications. Results: Hepatolithiasis was seen in nine (0.34%) out of 2,600 patients being evaluated for gallstone disease. Three patients were young, while the remaining six were in the middle-age group. Seven (78%) were females. The presenting symptoms were abdominal pain (78%) and jaundice (22%). Hepatolithiasis was located in the left, right and bilateral ductal systems in 5, 1 and 3 patients respectively. Concomitant cholelithiasis and choledocholithiasis was seen in 6 (66.6%) patients each. Liver resection for unilateral disease was done in 3 (33.3%) patients: left hepatectomy- (n=2) and left lateral segmentectomy (n=1). High bile duct exploration and bilio-enteric drainage was done in 5 patients. One patient required hepatolithotomy and T-tube drainage due to cholangitis. Complete stone clearance was achieved in 78% of patients. Complications included minor surgical site infection and cholangitis in two patients. Histopathology revealed recurrent pyogenic cholangitis. At median follow-up of 28 months, 78% are symptom-free. Conclusions: Hepatectomy is an effective treatment when disease is confined to the left lobe. Combined surgical procedure is an acceptable option for bilateral or right-sided hepatolithiasis.
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Can insecticide mixtures be considered to surmount neonicotinoid resistance in Bemisia tabaci?
Roy Debashis,Biswas Sujan,Biswas Abhisek,Chakraborty Gautam,Sarkar Pijush Kanti 한국응용곤충학회 2022 Journal of Asia-Pacific Entomology Vol.25 No.2
Cotton whitefly, Bemisia tabaci is an important polyphagous pest worldwide. It is exposed to various chemical insecticides throughout the year, resulting in the rapid development of insecticide resistance. Mixtures of in secticides with distinct modes of action could enhance the toxicity of chemicals more effectively than sequences or rotations in resistant pest populations. Bioassays were conducted to study the efficacy of mixtures of neon icotinoid and ketoenol insecticides at different ratios against a laboratory susceptible (Lab-WB) and a neon icotinoid resistant (TMX-SEL) strain of B. tabaci Asia I. The results showed that mixtures of imidacloprid, acetamiprid, thiamethoxam or dinotefuran with spiromesifen at 1:1, 1:10 and 1:20 ratios and of imidacloprid, thiamethoxam or dinotefuran with spirotetramat at 1:1 ratio significantly increased (p < 0.05) toxicity to neonicotinoids in TMX-SEL strain. The combination indices of each tested neonicotinoids + ketoenols at 1:1 ratio and of acetamiprid + spiromesifen, and imidacloprid or dinotefuran + spirotetramat at 1:10 ratio for TMX-SEL strain were significantly below 1, suggesting synergistic interactions. The inhibitors PBO and DEF largely overcame resistance to the tested neonicotinoids, while none of the synergists significantly restored the sus ceptibility of B. tabaci to ketoenols. Increased activities of P450 monooxygenase and esterase were observed in TMX-SEL strain with an elevated 2.76 and 1.32-fold, respectively. Mixtures of neonicotinoids with spiromesifen or spirotetramat at a 1:1 ratio could be used to restore the neonicotinoid susceptibility in B. tabaci.
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