Potassium Channelopathies and Gastrointestinal Ulceration

( Jaeyong Han ),( Seung Hun Lee ),( Gerhard Giebisch ),( Tong Wang ) 대한소화기학회 2016 Gut and Liver Vol.10 No.6

Potassium channels and transporters maintain potassium homeostasis and play significant roles in several different biological actions via potassium ion regulation. In previous decades, the key revelations that potassium channels and transporters are involved in the production of gastric acid and the regulation of secretion in the stomach have been recognized. Drugs used to treat peptic ulceration are often potassium transporter inhibitors. It has also been reported that potassium channels are involved in ulcerative colitis. Direct toxicity to the intestines from nonsteroidal anti-inflammatory drugs has been associated with altered potassium channel activities. Several reports have indicated that the longterm use of the antianginal drug Nicorandil, an adenosine triphosphate-sensitive potassium channel opener, increases the chances of ulceration and perforation from the oral to anal regions throughout the gastrointestinal (GI) tract. Several of these drug features provide further insights into the role of potassium channels in the occurrence of ulceration in the GI tract. The purpose of this review is to investigate whether potassium channelopathies are involved in the mechanisms responsible for ulceration that occurs throughout the GI tract. (Gut Liver 2016;10:881-889)

손 검출 알고리즘 가속을 위한 시스템 구조 및 OpenCL을 활용한 병렬화 처리 연구

한재용(Jaeyong Han),한상필(Sangpil Han),채영석(Yeongseok Chae),김혁(Hyuk Kim),김성민(Seongmin Kim),구본태(Bontae Koo),이주현(Joohyun Lee) 한국정보과학회 2015 한국정보과학회 학술발표논문집 Vol.2015 No.6

전력선 모듈과 ZigBee 모듈을 이용한 홈 네트워크 게이트웨이 설계 및 구현

한재용(Jaeyong Han),이순흠(Sunheum Lee),김원겸(Wonkyum Kim),강영창(YeongChang Kang) 한국정보기술학회 2008 Proceedings of KIIT Conference Vol.2008 No.-

HLF(Haar-Like Feature)와 피부색 및 관심 영역 설정을 이용한 손 검출 알고리즘의 향상에 관한 연구

한상필(SangPil Han),한재용(JaeYong Han),채영석(YeongSeok Chae),김혁(Hyuk Kim),구본태(Bontae Koo),이주현(Joohyun Lee) 한국정보과학회 2015 한국정보과학회 학술발표논문집 Vol.2015 No.6

READ: Reliability Enhancement in 3D-Memory Exploiting Asymmetric SER Distribution

Han, Hyunseung,Chung, Jaeyong,Yang, Joon-Sung IEEE 2018 IEEE Transactions on Computers Vol.67 No.8

<P>3D-memory is one of promising applications in 3D-IC technology. With a 3D integration technology, the effective density of memories can increase and the interconnect distance from processor to memory can be shortened. Due to its stacked structure, the upper dies behave as shields blocking outer particles from reaching lower dies, and it makes error rate of the top layer largest among all layers. From a heat perspective, the lower dies would suffer from reliability problems since the lower dies are placed on top of logic die. The heat dissipation can more influence lower dies than upper dies. This creates unequal a reliability distribution for each layer in 3D-memories. A novel ECC organization scheme for 3D-memory to secure reliable operations under soft error rate (SER) profiles is introduced in this paper. The proposed scheme does not require additional redundant arrays. Instead, it utilizes unused spare columns of relatively reliable layer memories to store additional check-bits of less reliable layer memories. It forms a heterogeneous ECC organization across different layers which enhances ECC capabilities in less reliable layers. In addition, redundancy sharing scheme for yield enhancement can be implemented with the proposed scheme. Experimental results show that a memory with the proposed method can tolerate more than three times of a bit-error rate compared to the conventional memory.</P>

Temporal-spatial changes and contamination status of marine surface sediments in Gyeonggi bay, South Korea

Jaeyong Bae,Byungkwon Kim,Sungmin Kim,Juyeon Seo,Jungjo Han,Sangwoo Lee 한국수산과학회 양식분과 2021 한국수산과학회 양식분과 학술대회 Vol.2021 No.4

Exploring Gender Disparity in Capable Guardianship Against Identity Theft: A Focus on Internet-Based Behavior

Jaeyong Choi,Sungil Han,Randolph D. Hicks 한국형사법무정책연구원 2022 International Journal of Criminal Justice Vol.4 No.1

Despite the growing literature on identity theft, limited studies have been conducted to explore demographic differences between individuals in levels of self-protection measures. Additionally, previous research indicates that men are less likely to employ self-protection measures compared to women, but the potential mechanisms to explain this gender difference remain unclear. Using the 2016 Identity Theft Supplement of the National Crime Victimization Survey in the U.S., the current study examined the interrelationship between gender, Internet-based behaviors (e.g., online shopping, credit card use, and debit card use), and the use of self-protection measures. Our logistic regression models revealed that the use of debit cards to make purchases online mediates the relationship between gender and the decision to employ self-protection measures.

Factors Affecting the Quality of Life of Korean Cancer Survivors Who Return to the Workplace

Han, Kyu-Tae,Park, Eun-Cheol,Kim, Sun Jung,Jang, Sung-In,Shin, Jaeyong,Kim, Chan Ok,Choi, Jaw Woo,Lee, Sang Gyu Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.20

Background: Although the prevalence of cancer is increasing, it is no longer synonymous with death. The number of cancer survivors is estimated to be increasing due to development in medical treatments and social programs; cancer survivors are increasingly returning to work after long-term unemployment. Thus, we examined the quality of life (QOL) and the factors associated with return of cancer survivors to the workplace. Materials and Methods: This study was performed using the 2008 Community Health Survey administered by the Korea Centers for Disease Control and Prevention (N=548). We used Chi-square tests to compare demographic variables based on self-perceived health status, and analysis of variance (ANOVA) to compare QOL scores among groups. We also performed a mixed-model analysis of the relationship between QOL and factors at the workplaces of cancer survivors. Results: Based on the results of our study, the overall QOL of cancer survivors was associated with 'mutual respect', 'free emotional expression', occupation, and age. Moreover, different trends of QOL according to self-perceived health were identified on additional analysis. In the 'bad' self-perceived health group, QOL was significantly different according to income. The QOL of cancer survivors in the low-income group was lower than in the other groups. Conversely, the 'normal' group had a lower QOL caused by 'no mutual respect' and "no free emotional expression" in the workplace. The QOL in the 'good' group based on self-perceived health was higher in the younger age group. Conclusions: There may be a significant relationship between QOL and workplace factors for cancer survivors, although further study is needed to investigate this relationship in detail. This may facilitate formulation of policy and efforts to prevent and manage the decline in the QOL of cancer survivors returning to work.

Comparative Study on the Environmental Impact Assessment between the Republic of Korea and China - in case of golf courses -

( Jaeyong Choi ),( Young Han Kwon ),( Ick Cheol Jeong ),( Zhe Zhen Nan ),( Wei-hong Zhu ),( Ying Nan ),( Chunjing Li ) 한국환경연구원 2003 수시연구보고서 Vol.2003 No.-

1960년대부터 개발행위와 그에 따른 환경적 결과와의 관계가 주목을 받기 시작했고, 선진국에서는 이미 그러한 관계에 있어 의사결정단계에서 환경적요소가 고려될 수 있도록 제도적으로 보완이 되어왔다. 현재 한국과 중국에서는 비슷한 상황이 진행 중에 있는 시점에서 동 보고서는 환경영향평가의 비교연구를 통하여 양 국가의 환경보호에 관한 정책에 관한 이해증진에 목적이 있다. 동 보고서는 크게 두 부분으로 나뉘어 있다. 첫 번째 부분에서는 양국의 환경영향평가제도의 비교를 다루었는데, 양국의 환경영향평가는 1980년대부터 시작하였으나 본격적으로 시행된 것은 1990년대라 할 수 있다. 특히 한국은 1993년 환경영향평가법이 1993년 발효되고, 1999년 12월 통합영향평가법이 제정되었다. 중국의 경우 환경보전법에 의해 시행되어온 환경영향평가가 독립 법으로 2002년 제정되어 2003년 9월 발효되었다. 현재의 환경영향평가는 중국에서는 스크리닝을 통하여 대상사업이 환경에 미치는 영향 정도에 따라 환경영향평가서, 환경영향평가보고표, 환경보호관리등기표 등 3가지 분류에 따라 작성하도록 규정된 반면 한국에서는 17분야 64개 대상사업이 환경영향대상사업으로 규정되어있다. 또한 한국과는 다르게 중국에서는 환경영향평가 검토의견이 환경영향평가서에 반영되어 작성토록 되어있다. 주민공청회제도가 한국에서는 오랫동안 시행되어온 반면 중국에서는 새로운 법에서 주민의 참여가 처음으로 규정화 되었다. 마지막으로 중국에서는 각 성(省)에서 현재 자율적으로 환경영향평가 세부규정을 작성하고 있다. 두 번째 부분에서는 한· 중골프장에 대한 환경영향평가를 비교하였다. 양국의 평가서는 정부의 허가를 득한 대행업체가 작성하였다. 평가서의 검토과정은 비슷하였으나 운영면에서 약간 차이가 있었다. 한국의 경우 평가서 초안, 본안, 1, 2, 3차 보완서가 협의를 위해 작성되었으나 중국은 대강(大綱)과 평가서가 비준을 위해 작성되었다. 평가서 준비기간과 협의과정은 한국이 중국 보다 길었다. 골프장의 환경적 입지는 양국이 기후를 제외하고 비슷하였다. 한국의 평가서는 목록이 단순하나 여러 항목을 취급하고, 실제 상황을 반영하여 작성되기 보다 체계적이고 형식적인 면이 많았다. 반면 중국의 평가서는 한국과 정 반대였다. 중점평가항목은 한국이 8개 항목이었으며 중국은 3개항목이었다. 현황조사는 한국이 비교적 상세하고 구체적이었다. 생태계 평가를 위해 중국은 경관생태학적 기법을 적용하였으나 한국은 사용하지 않고 있다. 저감대책의 경우 한국은 공정에서 발생하는 영향을 반영하기 보다 정형화된 형식적인 포맷인데 비해 중국은 현실을 반영하여 영향을 예측하나 기술적인 방법들이 이론적이거나 저감대책으로 구체적이지 못한 경향이 있었다. 운영시 발생할 수 있는 문제가 한국에서는 수질, 생태계 훼손 등에서 발생할 수 있으며, 중국의 경우 도로사면의 훼손, 경관, 수질, 수문, 수생태계 등에서 발생할 가능성이 있었다. 주민의견의 수렴을 위해 한국은 초안에서 주민공청회와 설명회를 실시하였으며, 중국의 경우는 주민들을 대상으로 설문조사를 실시하였다. 동 보고서에서는 연구결과를 바탕으로 다음과 같은 환경영향평가에 관한 정책제언을 제시한다. 첫째, 환경영향평가는 의사결정을 위한 조언과정이지 의사결정단계가 아니라는 사회 인식증진의 노력이 필요하다. 둘째, 평가대상사업 결정의 유연성을 갖기 위해 한국에서는 스크리닝제도의 도입이 필요하다. 셋째, 환경에 대한 미래예측의 정확도를 높이기 위해서는 현재의 환경파악을 위한 환경정보시스템을 갖추어야 한다. 넷째, 국가자원의 효율성을 높이기 위하여 통합영향평가시스템의 실재적 운영이 필요하다. 마지막으로, 환경문제의 효율적인 해결을 위해 새로운 주민참여방식 필요하다. Since the 1960s, a growing` environmental awareness has increasingly focused attention on the interactions between development activities and their environmental consequences. In the developed countries this has led the environmental factors be explicitly considered in the decision-making processes. A similar situation is now occurring in Korea and China. In this regard, this study aims at contributing to a better knowledge of environmental conservation policies in both countries through the Environmental Impact Assessment (EIA) systems. This report is divided into twinfolds of EIA systems and case studies in Korea and China. The first part of the report reveals that although the EIA systems in both countries were initiated in 1980s, the actual supporting policies and actions began in the early 1990s. In Korea, the EIA Act was enacted in 1993, and this has been replaced by the Integrated Impact Assessment Act in December 1999. The independent law of EIA has been adopted in 2002 and enacted in September 2003 in China. Based on the current EIA regulations, while activities requiring EIA consists of 62 project types in 17 fields in Korea, China utilize the screening methods to decide the activities subject to the three EIA categories of Environmental Impact Statement (EIS), Environmental Impact Report Form, and Environmental Impact Registration Form. The EIA investigations are incorporated in an EIS, reversing Korean procedures in ter`minology. The newly adopted Chinese EIA Act includes the public participation as one of the processes while public hearing has long been a compulsory in the Korean EIA process. Finally, the detailed regulation of the EIA in China is prepared at the prefecture level to incorporate the local environment appropriately. At the second part of this report, case study on the EIA of golf course development comparison between Korea and China based largely on their EIS was carried out. The EIS of both countries were prepared by agencies who were certified by both governments. Review or inspection process of the EIS was similar, but operation was slightly different from each other. The draft, EIS, and 3 supplements were prepared and reviewed for approval of the EIA in Korea, whereas only the draft and EIS were prepared and inspected for ratification in China. The duration for EIS preparation and for approval processes in Korea are usually longer than in China. Natural environment of both sites was similar, except for the weather conditions. The EIS of Korea has a simple list, but treats various items, and try to focus on systematic and formal contents instead of reflection on the real situations. The EIS of China is opposite to that of Korea in terms of important assessment items selection. Korea had 8 items for the EIS, whereas 3 items for the China. Scope, season, and number of investigation on the item(especially ecosystem) are more detailed in the EIS of Korea, whereas they are comparatively not so specific in the EIS of China. An advanced assessment technique for ecosystem of the projected area, such as a landscape ecological method was applied in the Chinese EIA, but not in Korean EIA. The section of impact evaluation and mitigation methods in Korean EIS was written more likely by a fixed, superficial format rather than by specific reflection of environmental impacts generated by work processes. The techniques or methods of mitigation of Chinese EIS were theoretical and was not really specific to minimize the impacts. After the golf course development, problems might be raised in water quality, terrestrial and freshwater ecosystem, causing habitat alterations in Korea. In contrast, China is more concerned with damage of slope caused by road construction, scenery effect of building, water quality, hydrology, freshwater ecosystem. The method of public participation is different. Exhibition of the draft to public and an explanatory meeting are used in Korea to collect public opinions. Investigation of a questionnaire on the local residence is used to collect public opinions in China. The following policy recommendations were suggested based on the findings from this study: firstly, enhance the social awareness that EIA is a consultation process, not a final decision-making step; secondly, the screening system should be introduced in Korea for giving the flexibility of the EIA system; thirdly, to predict the future environmental situation more correctly, both Korea and China need an accumulated database; fourthly, practical integration of various impact assessment systems is needed for increasing the efficiency of national resource uses; and lastly, innovative and deliberative method of public participation approach should be adopted to solve the environmental problems efficiently.

Online multi-person tracking with two-stage data association and online appearance model learning

Jaeyong Ju,Daehun Kim,Bonhwa Ku,Han, David K.,Hanseok Ko IET 2017 IET computer vision Vol.11 No.1

<P>This study addresses the automatic multi-person tracking problem in complex scenes from a single, static, uncalibrated camera. In contrast with offline tracking approaches, a novel online multi-person tracking method is proposed based on a sequential tracking-by-detection framework, which can be applied to real-time applications. A two-stage data association is first developed to handle the drifting targets stemming from occlusions and people's abrupt motion changes. Subsequently, a novel online appearance learning is developed by using the incremental/ decremental support vector machine with an adaptive training sample collection strategy to ensure reliable data association and rapid learning. Experimental results show the effectiveness and robustness of the proposed method while demonstrating its compatibility with real-time applications.</P>