Secondary laparoscopic cytoreduction for recurrent ovarian cancer in case of laparoscopic primary debulking surgery

( Eunsaem Choi ),( Joong Sub Choi ),( Jaeman Bae ),( Won Moo Lee ),( Un Suk Jung ),( Jeong Min Eom ) 대한산부인과학회 2018 대한산부인과학회 학술대회 Vol.104 No.-

Objective: Teach a new procedure Target: Adanced practicioners Methods: Background and Aims: To investigate the feasibility of laparoscopic secondary cytoreduction in patients with recurrent ovarian cancer with previous laparoscopic primary debulking surgery Design: Case study. Patients: A 52-year-old Korean woman underwent laparoscopic secondary cytoreduction for recurrent ovarian cancer and previous laparoscopic primary debulking surgery. Interventions: Laparoscopy Results: A 52-year-old Korean woman had a laparoscopic primary optimal debulking surgery on September 22, 2015. The FIGO stage IIIC was confirmed and she received 12 cycles of paclitaxel/carboplatin chemotherapy. Since then, it had been checked as NED state for 6 months. During follow up, lab results showed elevation of CA125, and recurrence was confirmed by PET-CT imaging. We performed LAVH with BSO, CDS mass excision, pelvic and paralymphadenectomy during primary debulking surgery. In addition, diaphragm and omentectomy were performed. She received adjuvant chemotherapy with paclitaxel/carboplatin for 12 cycles. We performed the laparoscopic secondary cytoreductive surgery on November 28, 2017. Peritoneal cavity and diaphragm were clear and showed no metastatic nodule. Metastatic lymph nodes were confirmed along the left iliac vessels like seen in the previous PET-CT imaging and we resected them. What was seen as recurrence around right para-colic gutter area were metastatic nodule on the cecum surface. We removed the nodules and repaired the bowel serosa. She is receiving chemotherapy with stable disease at this time. Conclusion: Our experience indicate that laparoscopy is a feasible and safe approach to optimal cytoreduction for patients with recurrent ovarian cancer in case of laparoscopic primary debulking surgery.

Port site metastasis of high grade serous tubal cancer originated from serous tubal intraepithelial carcinoma (STIC)

( Eunsaem Choi ),( Won Moo Lee ),( Joong Sub Choi ),( Jaeman Bae ),( Jung Min Eom ),( Hyo Jin Lee ),( Jong Won Lee ) 대한산부인과학회 2018 대한산부인과학회 학술대회 Vol.104 No.-

On March 2, 2018, an 83-year-old woman visited our institute with right lower abdominal palpable mass. She has been undergoing treatment at nursing hospital for Alzheimers dementia, and the mass was palpable and growing before 3 months ago. Abdominal ultrasonography showed about 7 cm of mass and soft tissue leiomyomsarcoma was suspected, which did not communicate with intraabdominal organ. On April 19, 2018, she underwent mass excision on the right lower abdomen. Post-operative recovery was uneventful. She was consulted to our department because the final pathologic report was revealed high grade serous carcinoma originated Mullerian duct origin. On her past history, she performed laparoscopic assisted vaginal hysterectomy (LAVH) and bilateral salpingo-oophorectomy (BSO) due to uterine prolapse stage IV and right ovarian tumor. The histopathologic report of right ovary showed serous cystadenoma and both tubes were normal. We reviewed the slides retrospectively for high grade serous carcinoma of right ovary and the result was normal. However, we found serous tubal intraepithelial carcinoma (STIC) of right salpinx and final pathologic report was changed. Chest CT and PET-CT were performed for metastatic work up and there was no evidence of distant metastasis of other organs. We report the first case that port site metastasis of high grade serous carcinoma originated from STIC.

영미 아동 모험 소설에 관한 코퍼스 분석 연구: 『보물섬』을 중심으로

최은샘(Eunsaem Choi),정채관(Chae Kwan Jung) 한국콘텐츠학회 2021 한국콘텐츠학회논문지 Vol.21 No.1

본 연구에서는 대표적인 영미 아동 모험 소설 『보물섬』의 언어적 특징을 파악하기 위해 『보물섬』을 코퍼스화 하여 어휘, 리마, 키워드, n-그램을 분석하였다. 이 연구를 통해 고빈도 어휘가 텍스트의 핵심어라는 일반적인 주장과 달리 『보물섬』의 고빈도 어휘는 『보물섬』과 직접 관련이 없는 기능어, 고유명사 등이 최상위층에 포진하고 있다는 것을 발견하였고, 통계적인 방법으로 추출한 『보물섬』 키워드 역시 『보물섬』의 내용을 가늠하기에 충분하지 않음을 발견하였다. 따라서 1차 정량적인 키워드 분석 후 진행된 2차 정성적인 키워드 분석을 통해 추출한 30개의 핵심 키워드를 통해 『보물섬』 내용을 신속하고 구체적으로 파악하는 단초를 마련하였고, 이를 바탕으로 그동안 직관적으로만 회자 되던 『보물섬』에 나타난 남성성을 계량적으로 분석할 수 있었다. 또한, n-그램 분석을 통해 『보물섬』의 작가가 다른 작가에 비해 선호하고 자주 사용하는 연속어휘구를 발견하였고, 이를 토대로 문학 작품의 계량적 연구가 가능한 코퍼스 문체론 연구의 가능성을 탐색하였다. 본 연구를 통해 밝혀낸 연구결과가 영미 아동문학 콘텐츠의 확산과 코퍼스 문체론 연구에 도움이 되기를 희망한다. In this study, we analyzed the vocabulary, lemmas, keywords, and n-grams in 『Treasure Island』 to identify certain linguistic features of this British-American childrens adventure novel. The current study found that, contrary to the popular claim that frequently-used words are important and essential to a story, the set of frequently-used words in 『Treasure Island』 were mostly function words and proper nouns that were not directly related to the plot found in 『Treasure Island』. We also ascertained that a list of keywords using a statistical method making use of a corpus program was not good enough to surmise the story of 『Treasure Island』. However, we managed to extract 30 keywords through the first quantitative keyword analysis and then a second qualitative keyword analysis. We also carried out a series of n-gram analyses and were able to discover lexical bundles that were preferred and frequently used by the author of 『Treasure Island』. We hope that the results of this study will help spread this knowledge among British-American children’s literature as well as to further put forward corpus stylistic theory.

Successful laparoscopic repair with omental interposition of a recurrent vesicovaginal fistula after total laparoscopic hysterectomy and primary laparoscopic repair

( Jongwon Lee ),( Joong Sub Choi ),( Jaeman Bae ),( Won Moo Lee ),( Un Suk Jung ),( Jeong Min Eom ),( Eunsaem Choi ) 대한산부인과학회 2018 대한산부인과학회 학술대회 Vol.104 No.-

Objective: Teach a new procedure Target: Adanced practicioners Methods: We present the case of a 45-year old Korean women with a recurring vesicovaginal fistula after three weeks after laparoscopic primary repair of vesicovaginal fistula caused by a total laparoscopic hysterectomy. We performed a laparoscopic vesicovaginal fistula repair with omental interposition on June 28th, 2018. We encountered a large adhesion from prior surgery in the pelvic cavity, so performed adhesiolysis using a harmonic sheers. After adhesiolysis, we performed bilateral ureterolysis that continued to the posterior bladder until it reaches the vesicovaginal space, which is then sharply dissected laterally and distally until the fistula is encountered. A bulb syringe was used to mobilize the vaginal cuff so that the dissection of the vesicovaginal space and mobilization of the vagina could be performed easily. After adequate dissection and resection of the fistula tract from both the vagina and the bladder, a double-layer closure using 3-0 Vicryl was placed in a interrupted suture to secure the bladder. After the first layer of closure, the bladder was retrograde filled with 300cc of sterile water. Then second layer was closed in the same manner. And a single-layer closure of the vagina using a 1-0 Vicryl was placed transvaginally. After omental interposiotion to the fistula site, the procedure was over. There were no serious intraoperative or postoperative complications. Results: On postoperative day 14, the Foley catheter was removed and the patient has had no complication so far. Conclusion: Laparoscopic repair with omental interposition of a recurrent vesicovaginal fistula is feasible and effective.

Oncologic and Surgical Outcomes Laparoscopic Primary Debulking Surgery for Presumptive Advanced Epithelial Ovarian Cancer

( Ji Hyun Keum ),( Joong Sub Choi ),( Jaeman Bae ),( Won Moo Lee ),( Jung Min Eom ),( Hyo Jin Lee ),( Eunsaem Choi ) 대한산부인과학회 2018 대한산부인과학회 학술대회 Vol.104 No.-

Objective: This study aimed to compare the overall survival and disease free survival between laparoscopically-assisted staging surgery and laparotomic staging surgery for primary epithelial ovarian cancer. Methods: We reviewed clinical charts of women with epithelial ovarian cancer in tertiary Korean medical centers. We conducted the study using case-matched analysis to obtain equal cohorts of patients with respect to age, FIGO stage, histopathologic type, and tumor grade to assess surgical outcomes and survival. Results: Fifty-two patients (26 matched pairs) with epithelial ovarian cancer were selected to the study. There were no significant differences from two groups in terms of demographic and clinical characteristics. At a median follow-up of 69 months (range, 15-146 months), disease-free survival (P: 0.72) and overall survival (P: 0.53) were similar in both groups. Conclusion: Laparoscopically-assisted staging surgery did not show the differences in overall survival and disease free survival compared to laparotomic staging surgery. Laparoscopically-assisted staging surgery can be offered a treatment modality for selected women with advanced epithelial ovarian cancer.

Bioinformatics and integrated pharmacology network to identify the therapeutic targets and potential molecular mechanism of alpha-lipoic acid on primary ovarian insufficiency

( Deqi Kong ),( Heeryun Cho ),( Soowon Hwang ),( Jaeeun Lee ),( Eunsaem Choi ),( Ahyoung Lee ),( Ehnkyoung Choi ),( Yunbae Kim ),( Haijoong Kim ),( Sooncheol Hong ) 대한산부인과학회 2023 대한산부인과학회 학술대회 Vol.109 No.-

Uterocutaneous fistula after High-Intensity Focused Ultrasound : a case report

( Eunhyun Lee ),( Ji Hyun Keum ),( Jeong Min Eom ),( Jaeman Bae ),( Won Moo Lee ),( Joong Sub Choi ),( Eunsaem Choi ) 대한산부인과학회 2018 대한산부인과학회 학술대회 Vol.104 No.-

We report a case of uterocutaneous fistula in a 46-year-old woman who underwent High-Intensity Focused Ultrasound(HIFU). She is a Korean who lives in Kazakhstan. She had heavy menstrual bleeding and suspected of adenomyosis and myoma. She had been recommended for hysterectomy, but she never wanted to undergo hysterectomy, just treated with hormone therapy and received blood transfusions every few months. The patient finally received HIFU in Korea and returned to Kazakhstan shortly after. She felt fever and pain in the abdominal wall at the time of the procedure, and subsequently relived the pain but sustained discharge in that area and took antibiotics. Because of persistent heavy menstrual bleeding and pelvic pain, she recommended to receive hysterectomy in Kazakhstan. But she refused and underwent wound debridement and primary closure of abdominal wall injury at the hospital that performed HIFU in South Korea, and strongly rejected further surgery. Five months after the procedure, blood was drawn from the wounds of the abdomen at the time of menstruation and referred to our hospital. At the midline of abdominal ASIS level, a discharge was observed through the abdominal wall skin opening and there was extensive redness in the lower abdomen around that. The abdomen MRI showed a heterogenous myoma on the right side of the uterus and adenomyosis with a non-enhancing cavitary portion on the left side and fundus of the uterus, which appeared to be necrosis inside. The cavitary portion of the adenomyosis was suspected to be connected to the uterine cavity and formed fistulous tract through anterior abdominal wall. Peritoneal and fat infiltration around the tract was seen. So, she underwent total abdominal hysterectomy with bilateral salpingectomy in gynecology and abdominoplasty in plastic surgery. This is the first report of uterocutaneous fistula after HIFU procedure and it is important to keep in mind that this type of complication may occur when performing HIFU.