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Na, Eun Duc,Cha, Dong Hyun,Cho, Jung Hyun,Kim, Mi Kyoung The Korean Society for Reproductive Medicine 2012 Clinical and Experimental Reproductive Medicine Vol.39 No.4
Objective: Many studies have demonstrated that hydrosalpinx has a detrimental effect on the outcome of IVF. Treating hydrosalpinges prior to the IVF procedure in women with hydrosalpinges is thought to improve the likelihood of successful IVF outcome. Vaginal ultrasound-guided aspiration of hydrosalpinx fluid (HSF) with injection of the sclerosing agent in situ might be simpler than invasive procedures like salpingectomy. Therefore, we carried out a retrospective study on the effects of ultrasound-guided HSF aspiration and injection of the sclerosing agent of ultrasonically diagnosed hydrosalpinx on IVF outcome. Methods: In our retrospective study, 97 tubal factor infertile female patients that underwent IVF treatment between January 2005 and December 2012 at the Reproductive Medicine Center of CHA Hospital were divided into two study groups. Fifty-six patients underwent interventional ultrasound sclerotherapy (group 1), and the remaining 41 patients received laparoscopic salpingectomy (group 2) before IVF. We compared the IVF outcomes of the two groups. Results: The results showed that ultrasound-guided HSF aspiration and sclerotherapy have IVF outcomes comparable to laparoscopic salpingectomy. Conclusion: Interventional ultrasound guided sclerotherapy before IVF is an effective and less invasive prophylactic intervention alternative to salpingectomy with hydrosalpinx.
Case Report : Placental Mesenchymal Dysplasia Associated with Severe Preeclampsia: A case Report
( Eun Duc Na ),( Kyoung Jin Lee ),( Myung Joo Kim ),( Hyo Jin Yi ),( Ji Young Kim ) 대한산부인과학회 2011 Obstetrics & Gynecology Science Vol.54 No.8
Placental mesenchymal dysplasia (PMD) is a relatively recently recognized, rare placental vascular anomaly characterized by placentomegaly and grapelike vesicles that may coexist with a normal fetus. Ultrasonography performed at 16 weeks of gestation revealed multiple cysts in the placenta along with a morphologically normal fetus. At 24 weeks of gestational age, severe preeclampsia symptoms were seen. And sonographically intrauterine growth restriction (IUGR) and oligohydroamnios were noted. Based on the diagnosis of severe preeclampsia, termination of pregnancy was done. After termination, histopathologic examination of the placenta showed numerous grape-like cystic vesicles throughout the entire placenta and absence of trophoblastic proliferation and pseudoinclusions. We have described a pregnancy complicated with PMD associated with mid-trimester severe preeclampsia, IUGR and oligohydroamnios.
The effectiveness and feasibility of Vaginal myomectomy; A retrospective study of 27 cases
( Eun Duc Na ),( Hyeon Cheol Kim ) 대한산부인과학회 2012 대한산부인과학회 학술대회 Vol.99 No.-
The aim of this study was to establish the clinical effectiveness and safety of vaginal myomectomy via colpotomy in a series of consecutive procedures performed by one surgeon. We performed a retrospective study in Cha University Hospital between January 2000 and July 2013, involving 27 patients with symptomatic myomas . After a preoperative study such as transvaginal sonography, physical examination and history taking and so on, the patients underwent vaginal myomectomy. Characteristics of patients, position and size of myomas, operative data, perioperative complications, and length of hospital days were recorded. 27 women underwent vaginal myomectomy and conversion to laparotomy was not required in any cases. One achieved pregnancy after the procedure and underwent cesarean section .The median size of myomas was 68 mm (range 30-100). Seven patients underwent vaginal myomectomy under general anesthesia and 19 under spinal anesthesia, 1 under IV general. The median operating time was 67 min (range 35-135). 3 patiants with myoma at anterior position underwent vaginal myomectomy via anterior colpotomy and 24 patient with myoma at posterior position via posterior colpotomy. The estimated hemoglobin loss was 2.4 g/dL (range 0.2-5.8 g/dL). The average blood loss was 289 ml (range 50~800). No severe perioperative complications occurred. The median duration of hospital days (except operating day) was 2.8 day (range 2-6). 1 cases readmitted due to postoperative fever, but they discharged in a week without sequelae. A vaginal myomectomy seems to be considered an alternative to laparotomy or laparoscopy to treat symptomatic and accessible myomas.
( Ji Eun Jeong ),( Hyun Jung Kim ),( Ji Yeon Lee ),( Sung Woon Chang ),( Myung Jin Moon ),( Eun Hee Ahn ),( Ji Hyon Jang ),( Eun Duc Na ),( Hee Young Cho ) 대한산부인과학회 2016 대한산부인과학회 학술대회 Vol.102 No.-
목적: To compare the efficacy of progesterone versus cervical cerclage in preventing preterm birth in twin pregnancies with a history of preterm birth or presentation of a short cervix 방법: This was a retrospective study of twin pregnancies managed at Obstetrics and Gynecology, CHA Bundang Medical center from December 2007 to April 2016 using medical records. We included 432 patients with 28weeks of gestation or less who were diagnosed with a cervical length less than 25 mm or who had history of preterm birth. The study population were devided 4 groups including progesterone group (n=138), cervical cerclage group (n=21), progesterone with cerclage group (n=78) and conservative treatment group (n=195) and outcomes were compared among 4 groups. The primary outcome measures were spontaneous birth at <28, 32, 34, or 36 weeks of gestation. The secondary outcome measures included hospitalization for tocolytics, antenatal corticosteroids and small for gestational age. 결과: Incidence of spontaneous delivery at <34 weeks of gestation was 26.9% (21/78) and 13.8% (27/195) in the progesterone with cerclage group and conservative treatment group, respectively (OR 36.9, 95% CI 5.45-250.24, p<0.001). There was statistically significant differences received antenatal corticosteroid between two groups. (OR 4.39, 95% CI 1.29-14.98, p=0.018) 결론: In twin pregnancies where patients are diagnosed with short cervical length or with a prior preterm birth history, treatment of cervical cerclage with progesterone showed significantly greater occurrence of delivery before 34 weeks compared to conservative management.
( Houn Young Kim ),( Eun Duc Na ),( Sang Heum Kim ),( Mee Hwa Lee ) 대한산부인과학회 2014 대한산부인과학회 학술대회 Vol.100 No.-
목적: To assess the value of magnetic resonance imaging of the brain in the evaluation of female hypogonadotropic hypogonadism (HH) 방법: We conducted a retrospective review of 69 females (age range 14-42 years) with normoprolactinemic HH who underwent pituitary MRI at CHA Bundang Medical Center between July 2000 and June 2014. Most frequent indication for MRI was the presence of HH with no apparent nutritional or environmental causes. Among 69 patients, 31 (44.9%) presented with primary amenorrhea and 20 (29.0%) had no breast development. 결과: A mass lesion greater than 1 cm in diameter was noted in 7 (10.1%) patients and a hypoplastic pituitary gland in 17 (24.6%). Frequency of a mass lesion was 5% (1/20) in patients without breast development, 18.2% (2/11) in interrupted puberty and 10.5% (4/38) in secondary amenorrhea. Frequency of a hypoplastic pituitary gland was the highest in patients without breast development (8/20, 40%) and lowest in patients with secondary amenorrhea (6/38, 15.8%). Comparisons between patients with different MR findings showed no significant differences in age, BMI, proportion of underweight and proportion of low gonadotropin level (p>0.05). 결론: Pituitary MRI plays an important role in the diagnostic process of female HH, especially in patients with interrupted puberty.
( Mi Sun Kim ),( Gee Hoon Lee ),( Eun Duc Na ),( Ji Hyon Jang ),( Hyeon Chul Kim ) 대한산부인과학회 2016 Obstetrics & Gynecology Science Vol.59 No.3
Objective The purpose of this study was to evaluate the impact of pelvic organ prolapse (POP) repair on overactive bladder (OAB) symptoms in women with POP and the effect of baseline POP severity on improvement in OAB after surgical repair of POP. And we also tried to identify any preoperative factors for persistent postoperative OAB symptoms. Methods A total of 87 patients with coexisting POP and OAB who underwent surgical correction of POP were included and retrospectively analyzed and postoperative data was obtained by telephone interview. OAB was defined as an affirmative response to item no. 15 (urinary frequency) and item no. 16 (urge incontinence) of the Pelvic Floor Distress Inventory. POP severity was dichotomized by Pelvic Organ Prolapse Quantification stage 1 to 2 (n=22) versus stage 3 to 4 (n=65). Results OAB symptoms were significantly improved after surgical treatment (P<0.001). But there was no significant differences in postoperative improvement of frequency and urge incontinence between stage 1 to 2 group versus stage 3 to 4 group. Preoperative demographic factors (age, parity, and POP stage) were not significantly related to persistent postoperative OAB symptoms. Conclusion Women with coexisting POP and OAB who undergo surgical repair experience significant improvement in OAB symptoms after surgery, but severity of POP had no significant difference in improvement of OAB symptoms. Postoperative persistent OAB symptoms were not related to age, parity, body mass index, and POP stage.
김명주 ( Myung Joo Kim ),나은덕 ( Eun Duc Na ),이윤정 ( Yoon Jung Lee ),김미라 ( Mi La Kim ),성석주 ( Seok Ju Seong ),김지영 ( Ji Young Kim ) 대한산부인과학회 2012 Obstetrics & Gynecology Science Vol.55 No.3
Primary ovarian leiomyoma is a rare tumor, accounting for only 0.5%-1% of benign ovarian neoplasms. About 80 cases have been reported in the literature worldwide to date. Most cases are asymptomatic and usually found incidentally in routine gynecologic workup, during surgery, or at autopsy. Ovarian leiomyoma is difficult to be differentiated from other ovarian benign and malignant neoplasms, particularly from large ovarian solid tumors. It is important to consider ovary-preserving surgery as the first treatment modality in patients of reproductive age after excluding the possibility of malignancy, given that 80% of ovarian leiomyomas occur in premenopausal women and the size of the mass is larger in younger patients. Here we report a case of ovarian leiomyoma in a 38-year-old female patient who underwent laparoscopic excision of left ovarian mass and uterine myomectomy.
( Bo Bae Lim ),( Mi Sun Kim ),( Eun Duc Na ),( Hyeon Chul Kim ),( Mi Gang Kim ),( So Yeon Shin ),( Mee-hwa Lee ) 대한산부인과학회 2019 대한산부인과학회 학술대회 Vol.105 No.-
The Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome is characterized by congenital hypoplasia or aplasia of the uterus and agenesis of the upper part of the vagina. Here, we report the case of severe abdominal pain that was diagnosed as torsion of the right rudimentary uterine horn with multiple leiomyomas in a patient with MRKH syndrome. The twisted rudimentary uterine horn and multiple leiomyomas were successfully removed via laparoscopy. MRKH syndrome with uterine horn torsion is uncommon and ours is the first case of torsion in MRKH syndrome treated via a laparoscopic approach. Our report indicates that laparoscopy is ideal for the simultaneous diagnosis and treatment of pelvic massin MRKH syndrome.