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        Evaluation of Bone Density Measurement in Type 2 Diabetic Postmenopausal Women with Hypertension and Hyperlipidemia

        ( Emel Kiyak Caglayan ),( Yaprak Engin Ustun ),( Nagihan Sari ),( Seyhan Karacavus ),( Levent Seckin ),( Mustafa Kara ) 대한폐경학회 2015 대한폐경학회지 Vol.21 No.1

        Objectives: The aim of the study was to compare bone mineral density (BMD) in healthy postmenopausal women to BMD in type 2 diabetic hypertensive postmenopausal women with hyperlipidemia. Methods: Fifty type 2 diabetic and hypertensive postmenopausal women with hyperlipidemia and 51 age and body mass index (BMI) matched healthy postmenopausal women were included. Lumbar spine and femoral neck BMD were noted in both groups. BMD was measured using dual energy X-ray absorptiometry (DXA). Serum alkaline phosphatase (ALP), calcium and phosphorous were also measured. Pearson correlation coefficients were used to establish the relationship between various clinical characteristics. Results: There were no significant differences between two groups in respect to lumbar and vertebral BMD values, age, BMI, gravidity, parity. Serum cholesterol and fasting glucose levels were significantly different between each groups (P = 0.0001, P = 0.002). Conclusion: We found that, accompanying chronic diseases such as diabetes, hypertension and hyperlipidemia don’t affect the BMD measurements at postmenopausal period. So these postmenopausal women don’t have excess risk regarding osteoporosis. (J Menopausal Med 2015;21:36-40)

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        Factors Associated with Mammographic Density in Postmenopausal Women

        ( Emel Kiyak Caglayan ),( Kasim Caglayan ),( Ismet Alkis ),( Ergin Arslan ),( Aylin Okur ),( Oktay Banli ),( Yaprak Engin-ustun ) 대한폐경학회 2015 대한폐경학회지 Vol.21 No.2

        Objectives: Breast density increases the risk of breast cancer, but also in the interpretation of mammography is also important. This study examine the risk factors affecting breast density in postmenopausal women. Methods: Between January 2013 and January 2014, 215 patients admitted to The Clinics of Gynecology and Obstetrics with complaints of menopause were taken. According to the results of mammography, Group I (non-dense, n = 175) and Group II (dense, n = 40) were created. The informations of the caseswere analyzed retrospectively. Results: In Group I, body mass index (BMI), number of pregnancies, parity were significantly higher than group II (P < 0.05). In group II, the withdrawal period of menstruation and progesterone levels were significantly higher (P < 0.05). In logistic regression analysis, BMI for dense breasts and number of pregnancies were found to be an independent risk factor (P < 0.05). Conclusion: Increased BMI, pregnancy and parity, result of reduction in density , but longer duration of menopause and increased progesterone cause an increase in density. BMI and the number of pregnancy was found to be independent risk factors for reducing breast density. (J Menopausal Med 2015;21:82-88)

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        Association Between Overactive Bladder and Polyneuropathy in Diabetic Patients

        Nermin Tanik,Serhat Tanik,Sebahattin Albayrak,Kürsat Zengin,Levent Ertugrul Inan,Emel Kiyak Caglayan,Asuman Celikbilek,Kadir Kirboga,Mesut Gurdal 대한배뇨장애요실금학회 2016 International Neurourology Journal Vol.20 No.3

        Purpose: Diabetes mellitus (DM) is a chronic metabolic disorder that often leads to complications. We aimed to correlate two complications of DM, polyneuropathy and hyperactive bladder syndrome, using noninvasive measures, such as screening tests. Methods: We included 80 female and 40 male type 2 diabetic patients in this prospective study. Diabetic polyneuropathy evaluations were conducted using the Douleur Neuropathique 4 Questions (DN4), and overactive bladder (OAB) evaluations were performed using the Overactive Bladder Questionnaire (OAB-V8). The patients were also evaluated for retinopathy and nephropathy. The diabetic male and female patients with or without OAB were chosen and compared for microvascular complications (polyneuropathy, retinopathy, and nephropathy). Results: There were no significant correlations between OAB and retinopathy as well as between OAB and nephropathy among diabetic patients (female patients, P>0.05; male patients, P>0.05 ). However, the patients with OAB were significantly more likely to develop polyneuropathy (female patients, P<0.05; male patients, P<0.05). Conclusions: In diabetic patients, OAB and diabetic peripheral neuropathy are significantly correlated. These correlations were demonstrated using short, understandable, valid, and reliable disease-specific tests without invasive measures. Using these screening tests, both neurologists and urologists can easily diagnose these complications.

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