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황병덕,정웅재,최령,Hwang, Byung-Deog,Jung, Woong-Jae,Choi, Ryoung 보건의료산업학회 2011 보건의료산업학회지 Vol.5 No.1
This study aims at providing basic data on brain death by analyzing factors of influencing toward attitude to brain death subject to citizens of Busan City. The data was collected for 47 days from 14 July to 31 August, 2009. Among a total of 2200 cases of the questionaries, only 2042 cases were used. For data analysis, SPSS 17.0 was used, and for the specific analysis method frequency analysis to understand general characteristics of the participants. In addition, examination on T-test and ANOVA analysis were conducted after analyzing the factors for participants' consciousness on brain death, and logistic regression analysis for understanding of relations between participants' will to brain death and general characteristics. The results of this study are summarized as follows; First, attitudes towards brain death according to general characteristics was high in those with will to donate their organs than those without in the attitude factors, namely, death recognition, acceptive, exclusive and religious attitude factors. Second, Significant variables for effects of attitudes towards brain death were gender, patients or their family's chronic or incurable diseases, religion, occupation and death recognition, acceptive, and exclusive attitude factors.
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Immunomodulatory Effects of ZYM-201 on LPS-stimulated B Cells
이예은,김수찬,정웅재,이형수,김미연 대한면역학회 2014 Immune Network Vol.14 No.5
ZYM-201 is a methyl ester of triterpenoid glycoside fromSanguisorba officinalis which has been used for treatment ofinflammatory and metabolic diseases. In this study, immunomodulatoryeffects of ZYM-201 on B cells were examinedin vitro and in vivo. When splenocytes were activatedwith lipopolysaccharide (LPS), the major population whichhad shown an increase in cell numbers was B cells. However,when the B cells were treated with ZYM-201 after LPS activation,their cell numbers and the expression of major costimulatorymolecules, CD80 and CD86, were decreased. Furthermore, the effect of LPS, which induces activation ofNF-κB, was abolished by ZYM-201: LPS-stimulated B cellsshowed decrease of phosphorylation after treatment ofZYM-201. The same results were shown in vivo experiments. These results suggest that ZYM-201 may play a role in themodulation of inflammatory responses through inhibitingNF-κB activation and downregulating the expression of costimulatorymolecules on B cells.
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황병덕(Hwang, Byung-Deog),임복희(Im, Bock-Hee),정웅재(Jung, Woong-Jae) 한국산학기술학회 2011 한국산학기술학회논문지 Vol.12 No.1
본 연구는 부산시민을 대상으로 장기기증에 관련된 요인을 분석하여 장기기증에 관한 기초자료를 제공하고 나아가 본 조사로 인하여 장기기증에 관한 국민의식을 제고할 목적으로 시도되었다. 자료수집기간은 2009년 7월 14일부터 8월 31까지 47일 동안이었다. 자료의 수집방법은 설문조사로 총 2,200부를 배 부하여 2,042부를 최종분석 자료로 사용하였다. 자료 분석을 위해 한글 SPSS 17.0을 사용 하였으며, 대상자의 인구사회학적인 특성은 빈도분석을 실시하였다. 대상 자의 장기기증에 대한 태도는 요인분석 후 T-test 와 ANOVA 분석을 하였고, 장기기증의사에 영향을 미치는 인구사 회학적 특성을 파악하기 위하여 로지스틱 회귀분석을 실시하였다. 연구의 결과는 다음과 같다. 첫째, 대상자 중 장기기증에 대하여 들은 경험이 있는 경우는 71.6%이었다. 둘째, 인구사회학적 특성이 장기기증의사에 미치는 영향요인으로는 성별, 본인이나 가족의 만성병 또는 불치병여부, 종교, 수용적태도요인, 배타적태도요인 그리고 권유적태도요인이었다. 이상의 결과에서 장기기증에 대한 국민들의 인식도를 높이고 사회적 공감대를 형성하기 위해서는 무엇보다도 방송과 같은 대중적인 매스미디어를 통한 지속적인 대국민 홍보활동이 중요하며, 이러한 노력을 통하여 장기기증에 대한 인 식의 전환을 유도하여야 할 것이다. This study aims at providing basic data on organ donation by analyzing factors of influencing toward intention to organ donation and further at improving people's consciousness on organ donation, subject to citizens of Busan City. The data was collected for 47 days from 14 July to 31 August, 2009. Among a total of 2200 cases of the questionaries, only 2042 cases were used. For data analysis, SPSS 17.0 was used, and for the specific analysis method frequency analysis to understand general characteristics of the participants. In addition, examination on T-test and ANOVA analysis were conducted after analyzing the factors for participants' consciousness on organ donation, and logistic regression analysis for understanding of relations between participants' will to donate organs and general characteristics. The results of this study are summarized as follows; First, among the participants, those who have heard about organ donations were 71.6%. Second, the factors that general characteristics influence on the attitudes towards organ donation include gender, chronic diseases or incurable diseases in the respondents or their family, religion, acceptive attitude factor, exclusive attitude factor and positive attitude factor towards organ donation. Based on the results, in order to raise people's consciousness on organ donation and form social sympathy, more than anything else, public mass media like broadcasting is important. In addition, as organ donation centers and related institutions prepare nationwide events, we should endeavor to prepare the opportunities in various ways to converse people's consciousness on organ donation and further put organ donation into practice.
ScienceON
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