Symposium 3 : Early Events in Atherogenesis ; Innate and Adaptive Immunity: what do they play in Atherosclerosis

( Zhong Qun Yan ),( Goran K. Hansson ) 한국지질동맥경화학회 ( 구 한국지질학회 ) 2003 춘계학술대회 Vol.- No.-

The Operational Risks of Electricity Futures Based on Non-Storability of Electric Power

WU Zhong-qun 인하대학교 정석물류통상연구원 2009 인하대학교 정석물류통상연구원 학술대회 Vol.2009 No.10

Electricity futures emerged in 1990"s, and it was expected to bring electricity market efficiency and stability. However, the practice on electricity futures show that it can not efficiently prevent the fluctuation of market price, and eve the electricity futures market may go to collapse. Up to now, none of literatures clears the question. This paper gives the causes that lead up to the failure of electricity futures market by analyzing the internal interaction mechanism between electricity futures price and spot prices. First, electric power is not economically storable, as a result electricity futures exchange can not at all make an influence to electricity spot prices through inventory change; second, traders always modify the quotation on the basis of expectation about the state of electricity market in the future, so the expectation plays an important role for the prices of futures contracts. The paper concludes that the failure of electricity futures market can fundamentally be attribute to two reason: (1) non-storage of electric power, i.e. that electricity futures market inevitably goes to collapse if only the electricity can not be stored economically; (2) the instability of expectation, which will directly cause the fluctuation of prices in electricity market.

Expression and Functional Role of ALDH1 in Cervical Carcinoma Cells

Rao, Qun-Xian,Yao, Ting-Ting,Zhang, Bing-Zhong,Lin, Rong-Chun,Chen, Zhi-Liao,Zhou, Hui,Wang, Li-Juan,Lu, Huai-Wu,Chen, Qin,Di, Na,Lin, Zhong-Qiu Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.4

Tumor formation and growth is dictated by a very small number of tumor cells, called cancer stem cells, which are capable of self-renewal. The genesis of cancer stem cells and their resistance to conventional chemotherapy and radiotherapy via mechanisms such as multidrug resistance, quiescence, enhanced DNA repair abilities and anti-apoptotic mechanisms, make it imperative to develop methods to identify and use these cells as diagnostic or therapeutic targets. Aldehyde dehydrogenase 1 (ALDH1) is used as a cancer stem cell marker. In this study, we evaluated ALDH1 expression in CaSki, HeLa and SiHa cervical cancer cells using the Aldefluor method to isolate ALDH1-positive cells. We showed that higher ALDH1 expression correlated with significantly higher rates of cell proliferation, microsphere formation and migration. We also could demonstrate that SiHa-ALDH1-positive cells were significantly more tumorigenic compared to SiHa-ALDH1-negative cells. Similarly, SiHa cells overexpressing ALDH1 were significantly more tumorigenic and showed higher rates of cell proliferation and migration compared to SiHa cells where ALDH1 expression was knocked down using a lentivirus vector. Our data suggested that ALDH1 is a marker of cervical cancer stem cells and expand our understanding of its functional role.

Modeling of the Solubility of Solid Solutes in Supercritical CO2 with and without Cosolvent using Solution Theory

( Qun Sheng Li ),( Chong Li Zhong ),( Ze Ting Zhang ),( Qing Rong Zhou ) 한국화학공학회 2004 Korean Journal of Chemical Engineering Vol.21 No.6

Protein Cyclization Enhanced Thermostability and Exopeptidase-Resistance of Green Fluorescent Protein

( Zhong Lin Zhao ),( Xin Ma ),( Liang Li ),( Wei Zhang ),( Shu Zhen Ping ),( Ming Qun Xu ),( Min Lin ) 한국미생물 · 생명공학회 2010 Journal of microbiology and biotechnology Vol.20 No.3

Sequence Diversity in MIC6 Gene among Toxoplasma gondii Isolates from Different Hosts and Geographical Locations

Zhong-Yuan Li,Hui-Qun Song,Jia Chen,Xing-Quan Zhu 대한기생충학열대의학회 2015 The Korean Journal of Parasitology Vol.53 No.3

Toxoplasma gondii is an opportunistic protozoan parasite that can infect almost all warm-blooded animals including humans with a worldwide distribution. Micronemes play an important role in invasion process of T. gondii, associated with the attachment, motility, and host cell recognition. In this research, sequence diversity in microneme protein 6 (MIC6) gene among 16 T. gondii isolates from different hosts and geographical regions and 1 reference strain was examined. The results showed that the sequence of all the examined T. gondii strains was 1,050 bp in length, and their A + T content was between 45.7% and 46.1%. Sequence analysis presented 33 nucleotide mutation positions (0-1.1%), resulting in 23 amino acid substitutions (0-2.3%) aligned with T. gondii RH strain. Moreover, T. gondii strains representing the 3 classical genotypes (Type I, II, and III) were separated into different clusters based on the locus of MIC6 using phylogenetic analyses by Bayesian inference (BI), maximum parsimony (MP), and maximum likelihood (ML), but T. gondii strains belonging to ToxoDB #9 were separated into different clusters. Our results suggested that MIC6 gene is not a suitable marker for T. gondii population genetic studies.

중국 초등학생을 위한 교육관광콘텐츠 개발에 관한 연구

위군(Qun Wei),김금미(Kum-Mi Kim,),종전휘(Jian-Hui Zhong),이영구(Young-Koo Lee) 글로컬창의산업연구센터 2013 글로컬창의문화연구 Vol.- No.2

1992년 한중 수교 이후부터 한국을 방문한 중국 관광객의 수가 지속적으로 늘어났다. 1993년의 10만 명을 이어 1998년에는 21만 명으로 급속히 증가했고, 한중교류의 해를 맞이한 2007년에 중국인 방한관광객은 100만 명을 돌파하였다. 지리적으로 가까운 나라임에도 사회주의 체제 아래에 있었던 중국은 사회, 경제적으로 ‘가깝고도 먼 나라’로만 존재하였다. 사회주의 경제체제를 내려놓은 중국은 이제 동북아시대의 거점 국가로 대두하고 있다. 2008년 북경올림픽 및 상해세계엑스포를 계기로 중국인의 삶의 질이 한층 더 높아지고 있다. 유럽에서도 중국 관광객의 씀씀이를 주목하기 시작했다. 중국 관광객을 잡기 위해 쇼핑을 하는 그들을 위해 문화체험 프로그램과 연계할 필요성이 있다. 1970년대 초기부터 인구증가를 막기 위해 중국 정부는 ‘산아제한 정책’, 즉 계획생육(計劃生育) 정책을 폈다. 중국의 ‘산아제한 정책(계획생육정책)’은 효과적으로 많은 사회문제를 줄일 수 있었으나 자녀에 대한 지나친 관심과 사랑은 ‘소황제’라 일컫는 문제점을 낳았다. 중국의 주류 사회를 이루고 있는 이들은 중국인의 국민성에도 많은 영향을 미치고 있다. 중국의 부정적 이미지와 함께 ‘소황제’의 사회시스템 일탈로 전반적인 사회문제를 야기하고 있다. 이에 중국 정부와 부모는 미래 인재로 자녀의 바른 경제관념과 직업을 선택하게 해야 할 필요성이 생겼다. 따라서 본 연구의 대상은 중국 미래의 주류 사회의 근간이 될 아동을 대상으로 한다. 이와 같은 연구 대상은 공적인 부분과 사적인 부분을 효율적으로 반영하여 교육관광콘텐츠와 연계를 통해 발굴하고자 한다. 연구 대상으로, 부모와 함께, 혹은 학교 단체 활동의 이유로 한국에 입국하는 초등학생을 주목할 필요가 있다. 한국은 중국의 부모와 정부를 대신하여 놀이를 통해 초등학생의 직업체험을 수행하여 교육적 효과를 얻게 하고, 초등학생은 한국의 직업과 세계의 다양한 직업을 경험함으로써 한국을 재방문할 수 있게 될 것이다. After South Korea and The people"s Republic of China established diplomatic relations in 1992, the number of Chinese tourists visit the increasing. From one hundred thousand to 1993, to 1998, only five years short time grew to Two hundred and ten thousand, and in 2007 the "China-Korea Exchange Year" is a breakthrough in the one million. The 2008 Beijing Olympics and the Shanghai World Expo for the development of Chinese economy after the reform and opening up have a chance. Therefore, European countries have gradually begun to attract attention to Chinese tourists, because of not increasing overseas consumption of these sources and bring to China"s rapid economic development of the Chinese tourists. At the beginning of the year 1970, China in order to control the rapid growth of the population, the implementation of the policy of "family planning". China through the family planning policy to solve the social problems, but at the same time, only children brought about by the family of "Little Emperors(China one)" problem is increasingly significant. And this is also to China"s social, economic and cultural changes and development has deep influence, and become the new problems need to be solved in Chinese society. In this regard, the Chinese government and parents are aware of the necessity of a correct outlook on life and the economic concept of the child"s education. Therefore, the research on how to China"s one-child social and economic right outlook on education research, and through the research on the child education system in South Korea advanced, feasibility of development for Chinese children"s occupation experience educational tourism industry. Thus, not only to China"s onechild access to advanced national occupation education system, and solves the social problem in China at the same time, also promoted the Chinese and Korean entertainment education industry exchanges, but also promoted the development of Korean culture experience tourism industry.

Phase II Study on Voriconazole for Treatment of Chinese Patients with Malignant Hematological Disorders and Invasive Aspergillosis

Zhang, Xue-Zhong,Huang, Xin-En,Xu, Yan-Li,Zhang, Xiu-Qun,Su, Ai-ling,Shen, Zheng-Shan Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.5

Objective: To investigate the efficacy and safety of voriconazole in treating Chinese patients with hematological malignancies and invasive aspergillosis. Methods: From March 2007 to April 2012, patients with diagnoses confirmed by CT, GM test and/or PCR assays, were recruited into this study. Aspergillosis of all patients were treated with voriconazole 6 mg/kg intravenous infusion (iv) every 12 h for 1 day, followed by 4 mg/kg IV every 12 h for 10-15 days; Then, switch to oral administration that was 200mg every 12h for 4-12 weeks. Efficacy and safety were evaluated according to Practice Guideline of Infectious Diseases Society of America. Results: The overall response rate of 38 patients after voriconazole treatment was 81.6%. The median time to pyretolysis was 4.5 days. Treatment related side effects were mild and found in only 15.8% of cases. No treatment related deaths occurred. Conclusions: Voriconazole can considered to be a safe and effective front-line therapy to treat patients with hematological malignancies and invasive aspergillosis. Alternatively it could be used as a remedial treatment when other antifungal therapies are ineffective.

Elevated Serum Ferritin Levels in Patients with Hematologic Malignancies

Zhang, Xue-Zhong,Su, Ai-Ling,Hu, Ming-Qiu,Zhang, Xiu-Qun,Xu, Yan-Li Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.15

Purpose: To retrospectively analyze variability and clinical significance of serum ferritin levels in Chinese patients with hematologic malignancies. Materials and Methods: Serum ferritin were measured by radioimmunoassay, using a kit produced by the Beijing Institute of Atomic Energy. Patients with hematologic malignancies, and treated in the Department of Hematology in Nanjing First Hospital and fulfilled study criteria were recruited. Results: Of 473 patients with hematologic malignancies, 262 patients were diagnosed with acute leukemia, 131 with lymphoma and 80 with multiple myeloma. Serum ferritin levels of newly diagnosed and recurrent patients were significantly higher than those entering complete remission stage or in the control group (p<0.001). Conclusions: Serum ferritin lever in patients with hematologic malignancies at early stage and recurrent stage are significantly increased, so that detection and surveillance of changes of serum ferritin could be helpful in assessing conditions and prognosis of this patient cohort.

Solubility of D(−)-p-Hydroxyphenylglycine dane salt in binary methanol+isopropanol solvent mixtures

Zheng-Ming Yi,Qun-Sheng Li,Wei-Zhong Liu,Xu-Feng Sun 한국화학공학회 2010 Korean Journal of Chemical Engineering Vol.27 No.3

The solubility of D(−)-p-Hydroxyphenylglycine Dane Salt (HPGDane Salt) in binary methanol and isopropanol solvent mixtures was measured using a laser technique with the temperature range from 283.15 K to 323.15 K and mole fraction (x2) range from 0.0000 to 1.0000. The results were correlated with a semi-empirical equation.