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Yuqi Wang,Dongke Lv,Zhenglin Sun 보안공학연구지원센터 2016 International Journal of Security and Its Applicat Vol.10 No.6
According to “Pressure - State – Response” model, an eco-security assessment system was built which contains 32 indictors such as human activities, regional development index, etc. The results showed that: ecological security index of Zhalong Wetland Nature Reserve, appeared upward trend after the first drop in overall, but were all in warning category from 2007 to 2012. As for subsystem level, since 2007, pressure subsystem showed worsening trend, while the state and response subsystem appeared signs of improvement.
Forecasting on Ecological Security of Zhalong Wetland Nature Reserve based on Gray Theory
Yuqi Wang,Dongke Lv,Zhenglin Sun 보안공학연구지원센터 2016 International Journal of Security and Its Applicat Vol.10 No.8
Based on field survey data and statistics of Zhalong wetland natural reserve, gray correlation model was used to comprehensively analyze and forecast ecological security of zhalong. According to “Response -Pressure - State" model, a eco-security assessment system was built which contains 32 indictors such as human activities, regional development index, etc. The results showed that: Zhalong Wetland ecological security index varied from 0.6852-0.7951 from 2015-2022. The index of ecological security alternated "safer" from "early warning". Upward trend of ecological security benefited from implementation of policies from the response subsystem.
대황산(大黃酸)의 당뇨병쥐 신장조직섬유화 억제 효과에 관한 실험연구
조용걸,조정림,장걸,류홍봉,최영군,김상찬,김선형,Zhao, Rongjie,Zhao, Zhenglin,Zhang, Jie,Liu, Hongfeng,Cui, Rongjun,Kim, Sang Chan,Kim, Sun-Hyung 대한한의학방제학회 2013 大韓韓醫學方劑學會誌 Vol.21 No.1
Objectives : To investigate the therapeutic effect and underlying mechanisms of rhein on renal fibrosis in diabetic rats. Methods : Diabetic nephropathy (DN) was induced in adult Wistar rats via introperitoneal injection of streptozotocin (STZ) (20 mg/kg/d) for three consecutive days. Two days after the last dose of STZ, rhein was administered to the diabetic rats at a dose of 25 mg/kg or 50 mg/kg, twice a day by gavage, respectively. Following 28 days treatment with rhein, the plasma glucose and creatinine levels were measured, the renal levels of TGF-${\beta}1$ protein and mRNA were examined, and the fibronectin mRNA levels were also determined. Results : Rhein significantly inhibited the increased plasma glucose and creatinine levels of diabetic rats in a dose- and a time-dependent way. Immunohistochemical analysis showed both doses of rhein markedly attenuated elevated induction of renal TGF-${\beta}1$ protein expressions in diabetic rats. Additionally, the high dose of rhein improved both TGF-${\beta}1$ and fibronectin mRNA expressions, while the low dose of rhein only alleviated fibronectin mRNA expressions. Conclusions : Rhein can improve renal fibrosis in diabetic nephropathy rats, and which may be mediated through inhibition of the renal mRNA expressions of TGF-${\beta}1$ and fibronectin.