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Yuji Kasukawa,Naohisa Miyakoshi,Michio Hongo,Yoshinori Ishikawa,Daisuke Kudo,Ryota Kimura,Yuichi Ono,Jumpei Iida,Chiaki Sato,Yoichi Shimada 대한척추외과학회 2019 Asian Spine Journal Vol.13 No.5
Study Design: Retrospective and comparative study. Purpose: We assessed surgical treatment outcomes in patients with thoracic myelopathy due to ossification of the ligamentum flavum (OLF), and OLF combined with ossification of the posterior longitudinal ligament (OPLL) or vertebral fracture (VF) at the same level. Overview of Literature: OLF and OPLL cause severe thoracic myelopathy. Osteoporotic VF commonly occurs at the thoracolumbar junction. There have been no investigations of thoracic myelopathy due to OLF and VF. Methods: Forty patients were divided among three groups: the OLF group (n=23): myelopathy due to OLF, the OLF+OPLL group (n=12): myelopathy due to OLF and OPLL, and the OLF+VF group (n=5): myelopathy due to OLF and VF. We recorded OLF, OPLL, and VF sites and operative procedures. Each patient’s neurological status, according to the Japanese Orthopaedic Association (JOA) score, and walking ability were evaluated pre- and postoperatively. Results: Patients in the OLF+OPLL group were significantly younger than those in the other two groups. The preoperative JOA score was significantly lower in the OLF+VF than OLF group. The final JOA score was significantly lower in the OLF+VF than OLF and OLF+OPLL groups. The JOA score recovery rate was significantly lower in the OLF+VF than OLF group. Final walking ability was significantly worse in the OLF+OPLL and OLF+VF groups than in the OLF group and significantly worse in the OLF+VF than OLF+OPLL group. Conclusions: Thoracic myelopathy due to OLF+VF occurs primarily in older females, who also exhibit worse preoperative and postoperative neurological status, and worse walking ability, than patients with thoracic myelopathy due to OLF or OLF+OPLL.
Yuji Hotta,Naoya Ieda,Ayako Fukamoto,Tomoya Kataoka,Yoshihiro Kawade,Yasuhiro Maeda,Hidehiko Nakagawa,Kazunori Kimura 대한비뇨의학회 2016 Investigative and Clinical Urology Vol.57 No.3
Purpose: To investigate whether relaxation of the rat penile corpus cavernosum could be controlled with NOBL-1, a novel, light-controllable nitric oxide (NO) releaser. Materials and Methods: Fifteen-week-old male Wistar-ST rats were used. The penile corpus cavernosum was prepared and used in an isometric tension study. After noradrenaline (10-5 M) achieved precontraction, the penile corpus cavernosum was irradiated by light (470–500 nm) with and without NOBL-1 (10-6 M). In addition, we noted rats' responses to light with vardenafil (10-6 M), a phosphodiesterase-5 (PDE-5) inhibitor. Next, responses to light in the presence of a guanylate cyclase inhibitor, ODQ (1H-[1,2,4] oxadiazolo[4,3-a]quinoxalin-1-one) (10-5 M), were measured. All measurements were performed in pretreated L-NAME (10-4 M) conditions to inhibit endogenous NO production. Results: Corpus cavernosal smooth muscle, precontracted with noradrenaline, was unchanged by light irradiation in the absence of NOBL-1. However, in the presence of NOBL-1, corpus cavernosal smooth muscle, precontracted with noradrenaline, relaxed in response to light irradiation. After blue light irradiation ceased, tension returned. In addition, the light response was obviously enhanced in the presence of a PDE-5 inhibitor. Conclusions: This study showed that rat corpus cavernosal smooth muscle relaxation can be light-controlled using NOBL-1, a novel, light sensitive NO releaser. Though further in vivo studies are needed to investigate possible usefulness, NOBL-1 may be prove to be a useful tool for erectile dysfunction therapy, specifically in the field of penile rehabilitation.
Advantages and Applications of Synthetic Greases
Hiroshi KIMURA,Yuji ONUKI 한국트라이볼로지학회 2002 한국트라이볼로지학회 학술대회 Vol.2002 No.10
The numbers of synthetic greases have been developed with synthetic oils because of their excellent performance factors including thermal/oxidation stability, low-temperature fluidity and plastic compatibility. Long life under high-temperature condition and excellent low-temperature fluidity are required to serve as grease for bearings of engine room electrical component. As many plastics are used in place of metals for the purpose of weight saving, synthetic hydrocarbon grease is in use to avoid adverse effect on plastics. Other various special synthetic greases are also in use depending on specific, requirements like conductivity and vacuum condition.
Loss Analysis of Hybrid Electric Vehicle Inverters
Fumio Asakura,Norihito Kimura,Yuji Hayashi 전력전자학회 2019 ICPE(ISPE)논문집 Vol.2019 No.5
The analysis of electrical losses of hybrid electric vehicle (HEV) inverters is significant for improved fuel efficiency for HEVs. To analyze the breakdown of electrical losses in LA-4 Cycle or under other similar driving conditions, measurement and calculation methods have been developed to ascertain losses attributable to different parts of HEV inverters. To determine electrical losses, the methods use voltages and currents in HEV inverters measured with a vehicle-mounted virtual and real simulator (VRS)
Charge Density Distributions in Bi4Ti3O12 and Bi3.25La0.75Ti3O12 in the Paraelectric Phase
Chikako Moriyoshi,Sayaka Kimura,Yoshihiro Kuroiwa,김수재,Yuji Noguchi 한국물리학회 2009 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.55 No.2
The electron charge density distributions of the bismuth layered ferroelectric materials Bi4Ti3O12 (BiT) and Bi3.25La0.75Ti3O12 (BLT) in the paraelectric phase are demonstrated by analyzing the high-energy synchrotron-radiation powder-diffraction data on the basis of the maximum entropy method (MEM)/Rietveld method. The crystal structures of BiT and BLT are quite similar, and no significant difference is observed in the chemical bonding nature in the paraelectric phase. This result differs from the experimental fact that, in the ferroelectric phase, electron orbital hybridization between Bi and O in the perovskite layer is formed along the a-axis in BiT while the hybridization between Bi/La and O is revealed not only along the a-axis but also along the b-axis in BLT. We attribute the unchanged Curie temperatures for the Bi4−xLaxTi3O12 system to the same crystal structures, including the chemical bonding nature, in the paraelectric phase. The electron charge density distributions of the bismuth layered ferroelectric materials Bi4Ti3O12 (BiT) and Bi3.25La0.75Ti3O12 (BLT) in the paraelectric phase are demonstrated by analyzing the high-energy synchrotron-radiation powder-diffraction data on the basis of the maximum entropy method (MEM)/Rietveld method. The crystal structures of BiT and BLT are quite similar, and no significant difference is observed in the chemical bonding nature in the paraelectric phase. This result differs from the experimental fact that, in the ferroelectric phase, electron orbital hybridization between Bi and O in the perovskite layer is formed along the a-axis in BiT while the hybridization between Bi/La and O is revealed not only along the a-axis but also along the b-axis in BLT. We attribute the unchanged Curie temperatures for the Bi4−xLaxTi3O12 system to the same crystal structures, including the chemical bonding nature, in the paraelectric phase.