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- 저자 : Yuan-Hao Chiang (검색결과 3 건)
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Yuan-Hao Chen,Yung-Hsiao Chiang,Hsin-I Ma 대한신경과학회 2014 Journal of Clinical Neurology Vol.10 No.2
Background and Purpose Hypoxia, or ischemia, is a common cause of neurological deficits in the elderly. This study elucidated the mechanisms underlying ischemia-induced brain injury that results in neurological sequelae. Methods Cerebral ischemia was induced in male Sprague-Dawley rats by transient ligationof the left carotid artery followed by 60 min of hypoxia. A two-dimensional differential proteome analysis was performed using matrix-assisted laser desorption ionization-time-of-flightmass spectrometry to compare changes in protein expression on the lesioned side of the cortexrelative to that on the contralateral side at 0, 6, and 24 h after ischemia. Results The expressions of the following five proteins were up-regulated in the ipsilateralcortex at 24 h after ischemia-reperfusion injury compared to the contralateral (i.e., control)side: aconitase 2, neurotensin-related peptide, hypothetical protein XP-212759, 60-kDa heatshock protein, and aldolase A. The expression of one protein, dynamin-1, was up-regulatedonly at the 6-h time point. The level of 78-kDa glucose-regulated protein precursor on the lesioned side of the cerebral cortex was found to be high initially, but then down-regulated by 24 hafter the induction of ischemia-reperfusion injury. The expressions of several metabolic enzymes and translational factors were also perturbed soon after brain ischemia. Conclusions These findings provide insights into the mechanisms underlying the neurodegenerative events that occur following cerebral ischemia.
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Shang-Hao Liu,Chen-Feng Kuan,Cing–Yu Ke,Ming-Yuan Shen,Chin-Lung Chiang 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.127 No.-
In this study, chitosan (CS) from fish waste was used to prepare bio-based environmentally friendly flameretardants. After the hydroxyl group (OH) of CS and the ammonium group (NH4 + ) of ammoniumpolyphosphate (APP) underwent reactions, they were filtered and dried to obtain CS-APP. The aminogroup of CS-APP then reacted with the epoxy group of 4,40-methylenebis(N,N-diglycidylaniline) (NDY)to form CS-APP-NDY. Isophorone diisocyanate, polyol, and 3-aminopropyltriethoxysilane reacted to formsilicon polyurethane. CS-APP-NDY was then mixed with Si-PU to prepare polymer composites. To determinethe structure, thermal properties, flame retardancy, and mechanical properties of the composites,Fourier-transform infrared spectroscopy, thermogravimetric analysis, limiting oxygen index (LOI), conecalorimetry, UL-94, thermal analysis-FTIR (TA-FTIR) spectroscopy, universal machine testing, scanningelectron microscopy, X-ray photoelectron spectroscopy, and Raman spectroscopy were performed. TheTGA results revealed that, after the addition of CS-APP-NDY, char yield increased from 0.5 wt% to 25.8wt%, and the thermal stability of pristine PU also improved. In addition, the LOI and UL-94 results indicatedthat, after the addition of CS-APP-NDY, the LOI increased from 18.2% to 26.3%, and the UL-94 levelimproved from ‘‘Fail” to V-1. Overall, these results indicated that the addition of CS-APP-NDY to pristinePU increased its flame-retarding performance.
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Hybrid Algorithm for Selecting Multimedia Network Connections in Heterogeneous Networks
Tein-Yaw Chung,Ibrahim Mashal,Fong-Ching Yuan,Yuan-Hao Chiang,Osama Alsaryrah 한국산학기술학회 2015 SmartCR Vol.5 No.6
The heterogeneity of mobile and wireless networks exposes mobile users to different access network technologies. In the past, many paradigms have been introduced, such as Always Best Connected (ABC) and Always Best Network Connection (ABNC), to meet user’s preferences. However, they fail to consider multimedia services consisting of video and data, besides voice, for both source and destination. This paper presents a new model called Always Best Multiple Network Connection (ABMNC) to support multimedia services. ABMNC is first formulated as a Multiple Attribute Decision Making (MADM) problem with an embedded utility-based Multiple Knapsack Problem (MKP). In order to reduce computation complexity, the MADM hierarchy of ABMNC is decomposed into a number of iterated sub-MADM hierarchies, and a hybrid Analytic Hierarchy Process (AHP) and a Simple Additive Weighting (SAW) scheme are used to solve them. A novel Heuristic Rate Allocation Algorithm (HRAA) is then presented to reduce the computation complexity of the assignment and rate allocation. Moreover, a comprehensive Heuristic Path Selection Algorithm (HPSA) is proposed to efficiently resolve the ABMNC hierarchy. Finally, computer simulation is performed to study ABMNC, and the results show that our approach, most of the time, chooses the optimal network connections.
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