다이어트 솔루션을 위한 다이어트 유형 도출 연구

고유정(Koh You-Jeong),최종훈(Choe Jong-Hoon) 한국디자인학회 2017 한국디자인학회 학술발표대회 논문집 Vol.2017 No.11

Molecular analysis of S gene of spike glycoprotein of winter dysentery bovine coronavirus circulated in Korea during 2002–2003

Jeong, Jae-Ho,Kim, Gye-Yeop,Yoon, Soon-Seek,Park, Su-Jin,Kim, You-Jung,Sung, Chang-Min,Shin, Sung-Shik,Lee, Bong-Joo,Kang, Mun-Il,Park, Nam-Yong,Koh, Hong-Bum,Cho, Kyoung-Oh Elsevier 2005 Virus research Vol.108 No.1

<P><B>Abstract</B></P><P>Since the molecular analysis of spike (S) glycoprotein gene of bovine coronavirus (BCoV) has been conducted and compared mainly among American and Canadian isolates and/or strains, it is unclear whether BCoV circulated in the other countries are distinctive in genetic characteristics. In the present study, we analyzed the S glycoprotein gene to characterize 10 winter dysentery (WD) coronavirus strains circulated in Korea during 2002–2003 and compared the nucleotide (nt) and deduced amino acid (aa) sequences with the other known BCoV. The phylogenetic analysis of the entire S glycoprotein gene revealed that the aa sequences of all Korean WD strains were more homologous to each other and were very closely related to respiratory bovine coronavirus (RBCV) strain OK and enteric bovine coronavirus (EBCV) strain LY-138, but were distinct from the other known BCoVs. Based on the phylogenetic analysis of the hypervariable region of the S1 subunit, all Korean WD strains clustered with the respiratory strain OK, BCQ3994 and the enteric strain LY-138, while the Canadian BCQ calf diarrhea and WD strains, and the American RBCV LSU, French EBCV F15 and avirulent VACC, L9, and Mebus strains clustered on a separate major branch. These data suggest that the WD strains circulated in Korea had a genetic property of both RBCV and EBCV and were significantly distinct from the ancestral enteric strain.</P>

Development of multiple skin malignancies caused by arsenic exposure and PUVA treatment

( You Jin Jung ),( Ju Wang Jang ),( Dong Uk Cheon ),( Won Seon Koh ),( Jeong Eun Kim ),( Joo Yeon Ko ),( Young Suck Ro ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1

Arsenic is a metalloid which is considered to be a carcinogen to human, and the most common form of neoplasm is skin cancer. Chronic low dose arsenic exposure can result in increased risk of skin cancers even after the cessation of exposure. Recent studies suggest arsenic exposure increases the risk of nonmelanoma skin cancer as a cofactor to smoking and sunlight exposure. A 38-year-old man presented with multiple pigmented papules and plaques for 4 years and multiple keratoses and pits on his palms and soles for years ago. He treated with psoralens and ultraviolet A light (PUVA) therapy several years ago and had a history of taking herbal medicine for 3 years. Histologically basal cell carcinoma of chest and neck, and Bowen’s disease on abdomen were observed. Additional laboratory test for urine arsenic concentration was measured as 330.71 μg/day, which was higher than normal range. Herein, we report a case of multiple skin cancer due to PUVA and chronic arsenic exposure. Exposure to arsenics bears a life-long health hazard with the delayed development of skin cancer. PUVA can induce a partial response. It is remarkable that a relatively short exposure to arsenics can cause ongoing health hazards with cofactor. We cannot overemphasize the importance of thorough history taking when confront with unusual clinical manifestations like this case and clinician advise them further long-term follow up.

Three cases of radiation dermatitis after percutaneous coronary interventions

( You Jin Jung ),( Ju Wang Jang ),( Dong Uk Cheon ),( Won Seon Koh ),( Jeong Eun Kim ),( Joo Yeon Ko ),( Young Suck Ro ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1

Radiation dermatitis (RD) is induced by the subsequent inflammatory response after radiation exposure (RE). Imbalance of proinflammatory and profibrotic cytokines occurs after irradiation and lasts for months or even several years. Acute phase of RD is often defined as the changes seen within 90 days following RE, presenting mild erythema and dry skin. Chronic RD is defined as changes that occur more than 90 days after RE showed atrophy, telangiectasia, sclerosis, ulcerations and premalignant or malignant neoplasms. Its incidence is growing because the number of interventional radiology procedures is increasing. We experienced three cases of RD manifested as erythematous to brownish indurated plaques with ulcer on the percutaneous coronary interventions (PCI) irradiation field. They had history of coronary artery disease and had undergone prolonged PCI lasting for more than 3 hours. The disease onset time after PCI ranged from 2 to 8 months. Histopathologic findings consist with RD. Therefore, we present three cases of patients with RD developed after PCI. To our best knowledge, chronic RD after PCI has been rarely reported in Korean literatures. Clinicians should consider RD as a differential diagnosis when an indurated patch or plaque occurs in patients who underwent PCI. Because early intervention can definitely shorten the disease course, close monitoring is needed for the patients underwent PCI.

A case of pilomatricoma on sole

( You Jin Jung ),( Ju Wang Jang ),( Dong Uk Cheon ),( Won Seon Koh ),( Jeong Eun Kim ),( Joo Yeon Ko ),( Young Suck Ro ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1

Pilomatricoma is a benign skin adnexal tumor derived from hair matrix cells. It usually presents as a solitary, skin-colored or bluish, firm, nodule in any part of the body except the palms and soles which do not have hair follicles. Etiologic factors are not well known but trauma has been implicated as an etiological factor. To our best knowledge several reports regarding pilomatricoma on digit have been reported and which regarding on sole has not been reported in the English literature. A 15-year-old boy presented with a painful solitary erythematous papule on left sole. He had a plantar wart 4 months ago in the same location where the papule was located. He had a history of treatment including cryotherapy and bleomycin injection for wart, for 9 months. Excisional biopsy was performed for a 3 mm sized papule. From the histopathologic examination, a well-demarcated tumor was in dermis with solid nests of basaloid cells undergoing abrupt trichilemmal type keratinization. Ghost cells were seen with calcification. Based on these findings, he was diagnosed as pilomatricoma. The papule was completely excised and there was no recurrence for a year. Herein, we report the first case of pilomatricoma on sole. The presence of hair follicle structure must precede the formation of pilomatricoma, therefore, we suggest the potential of implantation of hair matrix cells on sole, which is driven by repeated trauma due to repeated wart treatment.

The Activity-Oriented Usability Model of Software

Koh, Seokha,Koh, You-Jeong Korea Data Strategy Society 2018 Journal of information technology applications & m Vol.25 No.3

In this paper, an activity-oriented usability model is proposed. The usability model contains two types of characteristics: special-type characteristics of usability and sub-characteristics of usability. Workability, study-ability, and playability are, but do not exhaust, examples of special-type characteristic of usability. They correspond to working, studying, and playing using the software product, respectively. They represent the goal of using and can overlap each other. They are usability too by themselves. Navigate-ability, data-prepare-ability, data-input-ability, response-wait-ability, output-examine-ability, and output-utilize-ability are typical examples of sub-characteristics of usability. They correspond to navigating, preparing data, inputting data, waiting response, examining output, and utilizing the output data, respectively. They are not usability by themselves. They constitute usability together as a group. Assessing is the fundamental and indispensable aspect of quality. Without assessing, the concept of quality has little practical value. Satisfaction, effectiveness, and efficiency are the most typical sub-characteristics of usability in existing quality models, which correspond to the evaluation criteria of usability. In the activity-oriented usability model, however, only the user's satisfaction is included: Satisfaction is regarded as the operational definition of usability in the user's view. As the result, usability can be interpreted as the 'goodness for using, which is evaluated by the user. 'Three fundamental principles regarding software quality models are proposed too in this paper: Principles of Parsimony, Cohesiveness, and Inheritance. Discussions illustrate well that typical existing usability models violate these basic principles. Many authors have tried to define general usability models which can be applied to most kinds of software. The dream of the general and universal usability model, however, may be an illusion. The activity-oriented usability model is expected to serve as a prototype from which specialized usability models can be derived.

A case of eosinophilic dermatitis associated with toxocariasis

( You Jin Jung ),( Ju Wang Jang ),( Dong Uk Cheon ),( Won Seon Koh ),( Jeong Eun Kim ),( Joo Yeon Ko ),( Young Suck Ro ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1

Toxocariasis is a parasitic infection with worldwide distribution, but it is steadily decreased along with public health improvement from 1980s in Korea. Human infection is caused by ingesting the eggs shed in the feces of dog or cat. Toxocariasis is often resolve itself, but it could migrate to internal organs like lung or liver that should be treated by antihelminthic agents. A 61-year-old man presented with a solitary brownish nodule on chest for several weeks. He had a history of eating raw fish and horseflesh. He had no other systemic symptoms such as fever and abdominal discomfort, but peripheral blood hypereosinophilia (4200/uL) and increased total Immunoglobulin (Ig) E level (26099 IU/mL) were checked up. Also, there were multiple low-density masses in liver on abdomen CT. Histopathologic examination of chest nodule showed diffuse cellular infiltration of lymphocytes, eosinophils and neutrophils in dermis and he was positive to serum IgG for Toxocara canis. From these findings, he was diagnosed with toxocariasis and received a treatment course of 400 mg of albendazole twice a day for 5 days. After the conventional antiparasitic treatment, the eosinophil count was still high. Therefore he got additional high dose albendazole treatment and it was gradually normalized. Herein, we report a case of toxocariasis presenting eosinophilic dermatitis with eosinophilic infiltrate in liver, which could be need high dose albendazole therapy.

Spontaneous regression with halo phenomenon in congenital melanocytic nevus after staging operations

( You Jin Jung ),( Ju Wang Jang ),( Dong Uk Cheon ),( Won Seon Koh ),( Jeong Eun Kim ),( Joo Yeon Ko ),( Young Suck Ro ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1

Congenital melanocytic nevus (CMN) is a neural crest derived hamartoma, which appears at or soon after birth. CMN has a dynamic course and may show variable changes, including spontaneous regression. Spontaneous involution with a halo is a rare phenomenon. The mechanism is suggested to be a destruction of melanocytes by immune responses of cytotoxic T cells or IgM autoantibodies and it may be triggered by UV radiation or local trauma. A 9-year-old boy presented with a 4.5x3 cm sized solitary brownish to blackish patch on right forearm which appeared since birth. Biopsy specimen showed cords and nests of nevus cells in the entire dermis, and infiltration of nevus cells in adnexal-centric fashion. Based on these findings, he was diagnosed with CMN. After the first incisional biopsy, halo was appeared around the lesion and after the second incisional biopsy, the lesion showed spontaneous involution especially around suture sites. From the histologic findings, involuted lesions revealed perivascular cellular infiltration composed of lymphohistiocytes and decreased nevus cells. After the sixth incisional biopsy, his lesion was completely disappeared. Herein, we report an interesting case in which surgical procedures act as a triggering factor to CMN regression accompanied by a halo phenomenon.

The Activity-Oriented Usability Model of Software

Seokha Koh,You-Jeong Koh 한국데이타베이스학회 2018 Journal of information technology applications & m Vol.25 No.3

In this paper, an activity-oriented usability model is proposed. The usability model contains two types of characteristics: special-type characteristics of usability and sub-characteristics of usability. Workability, study-ability, and playability are, but do not exhaust, examples of special-type characteristic of usability. They correspond to working, studying, and playing using the software product, respectively. They represent the goal of using and can overlap each other. They are usability too by themselves. Navigate-ability, data-prepare-ability, data-input-ability, response-wait-ability, output-examine-ability, and output-utilize-ability are typical examples of sub-characteristics of usability. They correspond to navigating, preparing data, inputting data, waiting response, examining output, and utilizing the output data, respectively. They are not usability by themselves. They constitute usability together as a group. Assessing is the fundamental and indispensable aspect of quality. Without assessing, the concept of quality has little practical value. Satisfaction, effectiveness, and efficiency are the most typical subcharacteristics of usability in existing quality models, which correspond to the evaluation criteria of usability. In the activity-oriented usability model, however, only the user’s satisfaction is included: Satisfaction is regarded as the operational definition of usability in the user’s view. As the result, usability can be interpreted as the ‘goodness for using, which is evaluated by the user.’ Three fundamental principles regarding software quality models are proposed too in this paper: Principles of Parsimony, Cohesiveness, and Inheritance. Discussions illustrate well that typical existing usability models violate these basic principles. Many authors have tried to define general usability models which can be applied to most kinds of software. The dream of the general and universal usability model, however, may be an illusion. The activity-oriented usability model is expected to serve as a prototype from which specialized usability models can be derived.

Geology of the Deogsan-myeon area, Jecheon-gun, Chungcheongbuk-do, Korea: contact between the Choseon and Ogcheon supergroups

김유홍(You Hong Kihm),김정환(Jeong Hwan Kim),고희재(Hee Jae Koh) 대한지질학회 1996 지질학회지 Vol.32 No.7