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- 저자 : You Ho Ha (검색결과 264 건)
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Lee, Eung-Pill,Lee, Soo-In,Jeong, Heon-Mo,Han, Young-Sub,Lee, Seung-Yeon,Park, Jae-Hoon,Jang, Rae-Ha,Hong, Youg-Sik,Jung, Young-Ho,Kim, Eui-Joo,Lee, Sang-Hun,You, Young-Han The Ecological Society of Korea 2019 Journal of Ecology and Environment Vol.43 No.4
Background: Standing biomass, litter production, rate of litter decomposition, amount of litter on forest floor, and amount of soil organic carbon distribution were investigated from March 2016 to November 2018 in order to evaluate the ecosystem value through organic carbon distribution in the Pinus densiflora forest at Namsan, Seoul Metropolitan City. Results: The amount of organic carbon in the Pinus densiflora forest was 261.09 ton C ha<sup>-1</sup> during the research period, and fixed organic carbon in plant through net photosynthesis was 3.2 ton C ha<sup>-1</sup> year<sup>-1</sup>. The organic carbon in plant was 62.77 ton C ha<sup>-1</sup> (24.04%), in litter on the forest floor was 3.65 ton C ha<sup>-1</sup> (1.40%), and in soil was 194.67 ton C ha<sup>-1</sup> (74.56%). The value of plant, litter on forest floor, and soil organic carbon distribution were each 6,277,000 won ha<sup>-1</sup>, 365, 000 won ha<sup>-1</sup>, and 19,467,000 won ha<sup>-1</sup>. The value per ton of fixed organic carbon in plant through net photosynthesis was 320,000 won ha<sup>-1</sup> year<sup>-1</sup> and the value of ecosystem services stored in carbon in the Namsan forest ecosystem was about 26.1 million won ha<sup>-1</sup> for 3 years. Conclusions: The results of this study suggest that the pine forests of Namsan rapidly decompose leaves due to the high atmospheric temperature and accumulate a large amount of organic carbon in the soil to provide climate control regulatory service function.
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Oh, You-Chang,Jeong, Yun Hee,Cho, Won-Kyung,Ha, Jeong-Ho,Gu, Min Jung,Ma, Jin Yeul MDPI 2015 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.16 No.1
<P>Pyeongwisan (PW) is an herbal medication used in traditional East Asian medicine to treat anorexia, abdominal distension, borborygmus and diarrhea caused by gastric catarrh, atony and dilatation. However, its effects on inflammation-related diseases are unknown. In this study, we investigated the biological effects of PW on lipopolysaccharide (LPS)-mediated inflammation in macrophages and on local inflammation <I>in vivo</I>. We investigated the biological effects of PW on the production of inflammatory mediators, pro-inflammatory cytokines and related products as well as the activation of nuclear factor kappa B (NF-κB) and mitogen-activated protein kinases (MAPKs) in LPS-stimulated macrophages. Additionally, we evaluated the analgesic effect on the acetic acid-induced writhing response and the inhibitory activity on xylene-induced ear edema in mice. PW showed anti-inflammatory effects by inhibiting the production of nitric oxide (NO), tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) and interleukin-1β (IL-1β). In addition, PW strongly suppressed inducible nitric oxide synthase (iNOS), a NO synthesis enzyme, induced heme oxygenase-1 (HO-1) expression and inhibited NF-κB activation and MAPK phosphorylation. Also, PW suppressed TNF-α, IL-6 and IL-1β cytokine production in LPS-stimulated peritoneal macrophage cells. Furthermore, PW showed an analgesic effect on the writhing response and an inhibitory effect on mice ear edema. We demonstrated the anti-inflammatory effects and inhibitory mechanism in macrophages as well as inhibitory activity of PW <I>in vivo</I> for the first time. Our results suggest the potential value of PW as an inflammatory therapeutic agent developed from a natural substance.</P>
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Bacteriocin ("Vulnificin") Typing of Vibrio vulnificus
Ha, Tai-You,Lee, Jeong-Ho,Lee, Hern-Ku,Whang, Hee-Sung,Park, Jae-Seung The Korea Society for Microbiology 2000 大韓微生物學會誌 Vol.35 No.3
Vibrio vulnificus, a halophilic vibrio is an estuarine gram-negative bacteria that is associated with severe and frequently fatal wound infections and life-threatening septicemia. Bacteriocins are defined as antibacterial substance produced by various species of bacteria which are usually active against closely related organisms. Bacteriocins have found widespread application in epidemiological studies as specific markers of bacteria. It was proposed by Ha et al. (1990. J. Korean. Soc. Microbiol. 25: 586.) to give the bacteriocins produced by V. vulnificus the name "vulnificins". In the present study, a total of 72 strains of V. vulnificus isolated from patients and oysters were subjected to screen potential producers and indicators of vulnificin, applying ultraviolet induction method. Sensitivity of several strains of Serratia marcesans, Pseudomonas aeruginosa, Shigella flexneri, Salmonella typhi and Yersinia enterocolitica to vulnificins were also examined out. All the tested strains of V. vulnificus produced vulnificins active against indicator strains with various different inhibitory patterns. The spectrum of vulnificin activity and sensitive spectrum of indicator strains were considerably broad. Interestingly, almost all strains of S. marcescens, P. aeruginosa, Salmonella sp., Shigella sp. and Y. enterocolitica tested were sensitive to 1-7 vulnificin(s). Taken together, the present study demonstrated that all of the isolates of V. vulnificus produced vulnificins and that 8 good vulnificin producers and 10 good indicators were detected. These strains can be employed efficiently for establishing vulnificin typing scheme of V. vulnificus and for the detection of bacteriocinogeny and sensitivity in V. vulnificus. Biological role of vulnificin remains to be further elucidated.
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Bisphosphonate-related osteonecrosis of jaw의 치료에 대한 고찰
유경하(Kyung-Ha You),윤규호(Kyu-Ho Yoon),배정호(Jung-Ho Bae),박재안(Jae-An Park),박군찬(Gun-Chan Park),신재명(Jae-Myung Shin),백지선(Jee-Seon Baik),정정권(Jeong-Kwon Cheong) 대한구강악안면외과학회 2010 대한구강악안면외과학회지 Vol.36 No.3
Bisphosphonates are widely used to treat osteoporosis, hypercalcemia of malignant tumor. Despite their clinical benefit, bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a newly documented complication to patients receiving these drugs and first recognized by Marx in 2003. Thus, consideration of prevention and needs regarding unequivocal treatment regimen have emerged. Recently, several authors emphasized reports on appropriate clinical availability of surgical approach. It serves to concern about guideline for surgical and conservative treatment modalities. So, it is the purpose of this paper to review the current literatures about treatment regimens of BRONJ.
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簡單한 細菌學的 方法을 利用한 尿中 抗菌物質 檢索과 同定
河大有,李黃洙,金哲基 대한화학요법학회 1986 대한화학요법학회지 Vol.4 No.2
요(尿)와 혈청에서 항균물질을 검색하고 동정할 수 있는 간단한 세균학적 방법을 확인하고 확대시켰다. 이 간단한 방법을 이용하여 544가검요(可檢尿)를 검사하였든 바 이들로부터의 항생제 검출율은 13.6%(74가검물)이었다. 15가검물에서 항균제를 동정하였다. 이 검사방법은 신속하게 실시할 수 있고, 값이 저렴하고, 경험이 없는 사람도 실시할 수 있기 때문에 일상검사에 이 방법을 사용할 것을 제안하였다. A simple bacteriological method to detect and identify antibacterial substances in urine and serum were confirmed and extended. Employing this simple method, we have found that of 544 urine specimens from various sources, the frequency of finding antibiotics in urine specimens was 13.6%(74 specimens). The antibiotics was identified confidently with typical patterns of inhibitory zone in 15 urine specimens. As this method is neither time consuming nor expensive and can be set up by inexperienced laboratory personnel, we would like to propose this method to be used in routine laboratories.
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河大有,李正鎬 全北大學校 1977 論文集 Vol.19 No.-
The present experiments were carried out to study the effect of Panax ginseng on resistance to microbial infection in mice. The mice were intraperitoneally administered for 15 days with ginseng extract (daily 0.5mg in 0.25ml volume). The ginseng-treated and-untreated control mice were challenged with Salmonella typhimurium, Listeria monocytogenes, Staphylococcus aureus or Toxoplasma gondii, and assayed for resistance at various different intervals after challenge by determining the survival rate, the rate of clearance and the ingestion of microorganisms from the peritoneal cavity of mice. The rate of phagocytosis, denoted as the phagocytic index(K_1) was calculated from the equation K_1=(log Co-log C_1)/t, where Co is the concentration of bacteria at the time of ingestion, C_1 is the total concentration of viable bacteria in the peritoneal cavity, free or within phagocytic cells, at time t. Similarly, the rate of ingestion and the ingestion index(K_2) was calculated from the equation K_2=(log Co-log C_2)/t, where C_2 is the concentration of noningested bacteria free in the peritoneal exudate at time t. In some experiments, the organs' weights of the treated and untreated mice were measured at the various intervals after challenge. The survival rate of the ginseng-treated mice challenged with Salmonella typhimurium or Toxoplasma gondii was significantly higher than that of the untreated control mice challenged with the same organisms. The phagocytic and ingestion indices were significantly higher in ginseng-treated mice. When the ginseng-treated and -untreated mice were challenged with Toxoplasma gondii, the number of parasites in the peritoneal cavity was fewer in the treated mice than in the controls. When both ginseng-treated and-untreated mice were challenged with Staphylococcus aureus, however, the phagocytic and ingestion indices were somewhat lower in the ginseng-treated mice than in the controls. The weights of livers and spleens were heavier in the treated mice than in the controls. This was significantly apparent in the livers. These results led to the conclusion that the administration of ginseng extract into mice enhances generally the resistance of mice to intracellular microorganisms, whereas the administration of ginseng extract increases susceptibility to an extracellular bacteria, Staphylococcus aureus. Also, these results suggested that the mechanisms responsible for the enhancing effect of ginseng extract on resistance to intracellular microorganisms is due to nonspecifically increased cellular resistance.
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하상호,유재원,이상홍,신동민,표영배,안병관 朝鮮大學校 附設 醫學硏究所 1991 The Medical Journal of Chosun University Vol.16 No.2
The separation of symphysis pubis as a result of injury is uncommon, but it is increasing in number in parallel with today's speedy development of car industry. Most cases of the separation of symphysis pubis are amenable to closed treatments, but unstble separation where the reduction is difficult to maintain may require open techniques. Authors analyzed 27 cases of traumatic separation of symphysis pubis with 16 months follow-up on an average, who had been treated at the Orthopaedic Department, Chosun University Hospital. The results obtained were as follows; 1. The most common cause was traffic accident (81.5%). 2. Among of 27 patients, instability on the posterior stabilizer of pelvic bone was noticed in 18 patients. 3. Fifteen patients were treated with closed methods(bed rest, hammock, traction)and twelves were treated by the open reduction and internal fixation. 4. Internal fixations were carried out with plate and screw(5 cases), screw and wiring(4 cases), and wiring (3 cases). 5. The separation of symphysis pubis with minimal disruption of posterior stabilizer were treated by closed treatment or internal fixation of the separation of symphysis pubis diastasis alone, and its result was good or excellent. 6. We think that the symphysis pubis diastasis with severe disruption of posterior stabilizer should be fixed anteriorly and posteriorly both.
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