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        A new model and testing verification for evaluating the carbon efficiency of server

        Liang Guo,Yue Wang,Yixing Zhang,Caihong Zhou,Kexin Xu,Shaopeng Wang 한국인터넷정보학회 2023 KSII Transactions on Internet and Information Syst Vol.17 No.10

        To cope with the risks of climate change and promote the realization of carbon peaking and carbon neutrality, this paper first comprehensively considers the policy background, technical trends and carbon reduction paths of energy conservation and emission reduction in data center server industry. Second, we propose a computing power carbon efficiency of data center server, and constructs the carbon emission per performance of server (CEPS) model. According to the model, this paper selects the mainstream data center servers for testing. The result shows that with the improvement of server performance, the total carbon emissions are rising. However, the speed of performance improvement is faster than that of carbon emission, hence the relative carbon emission per unit computing power shows a continuous decreasing trend. Moreover, there are some differences between different products, and it is calculated that the carbon emission per unit performance is 20-60KG when the service life of the server is five years.

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        N6-Methyladenosine modification (m6 A) of circRNA-ZNF638 contributes to the induced activation of SHF stem cells through miR-361-5p/Wnt5a axis in cashmere goats

        Yin Ronghuan,Yin Ronglan,Bai Man,Fan Yixing,Wang Zeying,Zhu Yubo,Zhang Qi,Hui Taiyu,Shen Jincheng,Feng Siyu,Bai Wenlin 아세아·태평양축산학회 2023 Animal Bioscience Vol.36 No.4

        Objective: The objective of this study was to investigate the effects of N6-Methyladenosine modification-circRNA-zinc finger protein 638 (m6A-circRNA-ZNF638) on the induced activation of secondary hair follicle (SHF) stem cells with its potential mechanisms in cashmere goats. Methods: The m6A modification of ZNF638 was analyzed using methylation immunoprecipitation with real-time quantitative polymerase chain reaction technique in SHF stem cells. The effects of circRNA-ZNF638 on the induced activation of SHF stem cells in m6A dependence were evaluated through the overexpression of circRNA-ZNF638/its m6Adeficient mutants in circRNA-ZNF638 knockdown SHF stem cells. The competitive binding of miR-361-5p to circRNA-ZNF638/Wnt5a 3′- untranslated region was analyzed through Dual-luciferase reporter assay. Results: The m6A-circRNA-ZNF638 had significantly higher transcription at anagen SHF bulge of cashmere goats compared with that at telogen, as well as it positively regulated the induced activation of SHF-stem cells in cashmere goats. Mechanismly, m6A-circRNA-ZNF638 sponged miR-361-5p to heighten the transcriptional expression of Wnt5a gene in SHFstem cells. We further demonstrated that the internal m6A modification within circRNAZNF638 is required for mediating the miR-361-5p/Wnt5a pathway to regulate the induced activation of SHF stem cells through an introducing of m6A-deficient mutant of circRNAZNF638. Conclusion: The circRNA-ZNF638 contributes the proper induced activation of SHF-stem cells in cashmere goats in m6A-dependent manner through miR-361-5p/Wnt5a axis.

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