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RISS 인기검색어
- 검색키워드
- 저자 : Yingdong Qu (검색결과 2 건)
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Chen Qu,Wu Chen,Yao Zhihao,Cai Liuping,Ni Yingdong,Mao Shengyong 아세아·태평양축산학회 2022 Animal Bioscience Vol.35 No.8
Objective: High concentrate diets are widely used to satisfy high-yielding dairy cows; however, long-term feeding of high concentrate diets can cause subacute ruminal acidosis (SARA). The endocrine disturbance is one of the important reasons for metabolic disorders caused by SARA. However, there is no current report about thyroid hormones involved in liver metabolic disorders induced by a high concentrate diet. Methods: In this study, 12 mid-lactating dairy cows were randomly assigned to HC (high concentrate) group (60% concentrate of dry matter, n = 6) and LC (low concentrate) group (40% concentrate of dry matter, n = 6). All cows were slaughtered on the 21st day, and the samples of blood and liver were collected to analyze the blood biochemistry, histological changes, thyroid hormones, and the expression of genes and proteins. Results: Compared with LC group, HC group showed decreased serum triglyceride, free fatty acid, total cholesterol, low-density lipoprotein cholesterol, increased hepatic glycogen, and glucose. For glucose metabolism, the gene and protein expression of glucose-6- phosphatase and phosphoenolpyruvate carboxykinase 1 in the liver were significantly up-regulated in HC group. For lipid metabolism, the expression of sterol regulatory element-binding protein 1, long-chain acyl-CoA synthetase 1, and fatty acid synthase in the liver was decreased in HC group, whereas carnitine palmitoyltransferase 1α and peroxisome proliferator activated receptor α were increased. Serum triiodothyronine, thyroxin, free triiodothyronine (FT3), and hepatic FT3 increased in HC group, accompanied by increased expression of thyroid hormone receptor (THR) in the liver. Conclusion: Taken together, thyroid hormones may increase hepatic gluconeogenesis, β-oxidation and reduce fatty acid synthesis through the THR pathway to participate in the metabolic disorders caused by a high concentrate diet. Objective: High concentrate diets are widely used to satisfy high-yielding dairy cows; however, long-term feeding of high concentrate diets can cause subacute ruminal acidosis (SARA). The endocrine disturbance is one of the important reasons for metabolic disorders caused by SARA. However, there is no current report about thyroid hormones involved in liver metabolic disorders induced by a high concentrate diet.Methods: In this study, 12 mid-lactating dairy cows were randomly assigned to HC (high concentrate) group (60% concentrate of dry matter, n = 6) and LC (low concentrate) group (40% concentrate of dry matter, n = 6). All cows were slaughtered on the 21st day, and the samples of blood and liver were collected to analyze the blood biochemistry, histological changes, thyroid hormones, and the expression of genes and proteins.Results: Compared with LC group, HC group showed decreased serum triglyceride, free fatty acid, total cholesterol, low-density lipoprotein cholesterol, increased hepatic glycogen, and glucose. For glucose metabolism, the gene and protein expression of glucose-6-phosphatase and phosphoenolpyruvate carboxykinase 1 in the liver were significantly up-regulated in HC group. For lipid metabolism, the expression of sterol regulatory element-binding protein 1, long-chain acyl-CoA synthetase 1, and fatty acid synthase in the liver was decreased in HC group, whereas carnitine palmitoyltransferase 1α and peroxisome proliferator activated receptor α were increased. Serum triiodothyronine, thyroxin, free triiodothyronine (FT3), and hepatic FT3 increased in HC group, accompanied by increased expression of thyroid hormone receptor (THR) in the liver.Conclusion: Taken together, thyroid hormones may increase hepatic gluconeogenesis, β-oxidation and reduce fatty acid synthesis through the THR pathway to participate in the metabolic disorders caused by a high concentrate diet.
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Effect of Cyclic Deep Cryogenic Treatment on Corrosion Resistance of 7075 Alloy
Ruiming Su,Siyi Ma,Kaining Wang,Guanglong Li,Yingdong Qu,Rongde Li 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.4
The cyclic deep cryogenic treatment was proposed to improve both the hardness and corrosion resistance of the high strength7075 aluminum alloy. The effect of different CDCT times on the exfoliation corrosion and intergranular corrosion of the alloyswere observed by scanning electron microscope. The corrosion behaviors of the alloys were monitored by electrochemicaltechniques. The hardness of the alloy was measured by Vickers hardness tester. Furthermore, the microstructures of thealloys were examined by transmission electron microscope. The results show that the corrosion resistance and hardness arestrongly affected by the precipitate state. The discontinuous grain boundary precipitates and the wide precipitate free zoneswill enhance the corrosion resistance. The fine precipitates distributed evenly in the matrix can increase the hardness. Afterthe CDCT, the corrosion resistance is remarkably improved without sacrificing the hardness. The best combination of thehardness and corrosion resistance is exhibited for the alloy treated with the CDCT twice.
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