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      • KCI등재

        세가지 다른 인레이 와동 형태가 CEREC3 CAD/CAM의 변연 및 내면 간극에 미치는 영향

        서덕규,이영아,이윤,노병덕 大韓齒科保存學會 2009 Restorative Dentistry & Endodontics Vol.34 No.3

        이 연구의 목적은 세가지 다른 치아 삭제 형태에 따라 제작된 CEREC3 CAD/CAM의 인레이의 변연 및 내면 간극을 비교 평가하는 것이었다. CEREC3 인레이의 제작을 위해 다음의 제시된 방법에 따라 각 군당 10개의 시편을 준비하였다. 제Ⅰ군-기능 교두를 포함하는 전통적 방식의 capping과 shoulder margin, 제 Ⅱ군-교두를 수평으로 평평하게 삭제하는 단순화된 와동 형태, 제Ⅲ군-교두의 완전한 삭제와 shoulder margin을 갖는 가장 단순화된 형태로 세 군의 시편을 제작하였다. CEREC3로부터 제작된 인레이를 대응치아에 접착시킨 후, 치아 교합면의 중심을 지나게 협설면 방향으로 microsaw를 이용하여 절단하였다. 이후 Stereomicroscope을 사용하여 20배율에서 확대 영상을 촬영하였다. 그리고 미리 정해놓은 marginal, axial, angle, horizontal 기준점에서 Leica application suite 프로그램을 사용하여 시편과 치아 사이의 변연 및 내면 간극을 측정하였다. 일원분산분석을 사용하여 같은 기준 지점에서 세 군 사이의 차이를 분석하였으며, 각 군 안에서 여러 지점 사이의 차이 또한 알아보았다. Tukey's test로 95% 유의수준에서 사후 검정하였다. 세 군 모두에서 변연 부위에서 간극이 가장 작았으며, 변연 간극은 제Ⅰ군 80.0-97.8㎛, 제Ⅱ군 42.0-194.8㎛, 제Ⅲ군 51.0-80.2㎛의 범위를 나타내었다. 내면 간극은 제Ⅰ군 90.5-304.1㎛, 제Ⅱ군 80.0-274.8㎛, 제Ⅲ군 79.7-296.7㎛의 범위를 나타냈고 horizontal wall 부위에서 가장 큰 간극을 보였다. CEREC3 CAD/CAM시스템을 사용한 인레이 제작에 있어서 새롭게 제안된 두 가지의 단순화된 와동 형태는 변연 및 내면 간극이 전통적인 교두 피개 와동 형태보다 우수하지 않았다. The aim of this study was to evaluate the marginal and internal gaps in CEREC3 CAD/CAM inlays of three different preparation designs. CEREC3 Inlays of three different preparation designs (n = 10) were fabricated according to Group Ⅰ-conventional functional cusp capping/shoulder preparation, Group Ⅱ-horizontal reduction of cusps and Group Ⅲ-complete reduction of cusps/shoulder preparation. After cementation of inlays, the bucco-lingual cross section was performed through the center of tooth. Cross section images of 20 magnifications were obtained through the stereomicroscope. The gaps were measured using the Leica ap plication suite software at each reference point. Statistical analysis was performed using one-way ANOVA and Tukey's test(α < 0.05). The marginal gaps ranged from 80.0 to 97.8 ㎛ for Group Ⅰ, 42.0 to 194.8 ㎛ for Group Ⅱ, 51.0 to 80.2 ㎛ for Group Ⅲ. The internal gaps ranged from 90.5 to 304.1 ㎛ for Group Ⅰ, 80.0 to 274.8 ㎛ for Group Ⅱ, 79.7 to 296.7 ㎛ for Group Ⅲ. The gaps of each group were the smallest on the margin and the largest on the horizontal wall. For the CEREC3 CAD/CAM inlays, the simplified designs(groups Ⅱ and Ⅲ) did not demonstrate superior results compared to the traditional cusp capping design (group I).

      • KCI등재후보

        열공성 뇌경색과 뇌내출혈의 위험인자 비교

        이장준,이현아,최종환,이형,임정근,이상도,박영춘 계명대학교 의과학연구소 2000 계명의대학술지 Vol.19 No.2

        Cerebral small vessel disease is the most important cause of lacunar infarction (LI) and intracerebral hemorrhage (ICH). It is generally postulated that, in its early stages, the vascular lesion engenders vessel wall fragility and ICH. But if rupture dose not occur, segmental vessel occlusion evolves, producing LI. It may be a common aging phenomenon that is exacerbated by hypertension and diabetes mellitus. This study was performed to evaluate risk factors of LI and ICH. We reviewed retrospectively the medical records of 690 patients (254 LI, 436 ICH) with stroke who were admitted to Keimyung University Dongsan Medical Center from January 1995 to December 1998. The major risk factors including age, sex, hypertension, diabetes mellitus and several minor risk factors were analyzed in these patients. Older age (p<0.01), male sex(p<0.01), hypertension with treatment(p<0.01), hypertension with long duration(p<0.01) and hypertriglyceridemia(p<0.01), cigarette smoking(p<0.01) were significantly more frequent in LI. Younger age(p<0.01), female sex(p<0.01) and hypertension without treatment(p<0.01), hypertension with short duration(p<0.01) were more frequent in ICH. The prevalence, duration and treatment of diabetes mellitus were not different between these two groups. This study show that the age, sex, treatment of hypertension, duration of hypertension and cigarette smoking seem to be significant risk factors between LI and ICH.

      • Ex-situ Conservation of Horticultural Plant Genetic Resources in Genebank of Korea, National Agrobiodiversity Center

        Young-Yi Lee,Gyu-Taek Cho,Ho-Cheol Ko,Ho-Sun Lee,Young-Ah Jeon,Jung-Sook Sung,Sok-Young Lee,Chang-Yung Kim,Yeon-Gyu Kim 한국육종학회 2012 한국육종학회 심포지엄 Vol.2012 No.07

        The world-wide capacity of genebanks for ex-situ conservation of crop genetic resources has increased greatly since the 1970s, improving the access of crop breeders to landraces, and wild relatives (Wright, 1997). In south Korea, systematic seed germplasm management was begun at the Rural Development Administration (RDA) in 1985 and consequently genebank system was established in 1988. The RDA genebank, National Agrobiodiversity Center (NAC) of south Korea, preserve 173,217 accessions of plant seed germplasm and 10.7% (18,509 accessions) of whole preserved germplasm is occupied by horticultral PGR by 2011. Horticultural PGR preserved in NAC is composed with 67 genera of crops including pepper (3,817 accessions), tomato (2,040 accessions), cabbages (1,690 accessions) and etc. According to horticultural plant sub-group, fruit-vegetable is the biggest group with 60% of accession share and leafy vegetable (19%), root vegetable (10%), bulb vegetable (8%), and ornamental (3%) follow subsequently. In aspect of PGR status, landrace is dominant part of conserved accession and then developed cultivar, wild relatives, cultivated material, wild, and weedy type follow subsequently. Recently characterization and evaluation of horticultural PGR have been activated for 3 years in NAC, which are useful for breeders and users focused on disease-resistance or active ingredient. It will promote utilization of horticultural PGR and development of horticultural crop breeding program for both human being and sustainable agriculture in near future.

      • SCIESCOPUSKCI등재

        RESEARCH ARTICLES : Incidence, Molecular Characteristics and Pathogenicity of Gibberella fujikuroi Species Complex Associated with Rice Seeds from Asian Countries

        ( Young Ah Jeon ),( Seung Hun Yu ),( Young Yi Lee ),( Hong Jae Park ),( Sokyoung Lee ),( Jung Sook Sung ),( Yeon Gyu Kim ),( Ho Sun Lee ) 한국균학회 2013 Mycobiology Vol.41 No.4

        Gibberella fujikuroi species complex (GFSC) was isolated from rice (Oryza sativa L.) seed samples from ten Asian countries and investigated for incidence of GFSC, molecular characteristics, and pathogenicity. Regardless of geographic origin, GFSC was detected with incidences ranging from 3% to 80%. Four species, Fusarium fujikuroi, F. concentricum, F. proliferatum, and F. verticillioides, were found to show an association with rice seeds, with F. fujikuroi being the predominant species. In phylogenetic analyses of DNA sequences, no relationship was found between species, isolates, and geographic sources of samples. Unidentified fragments of the β-tubulin gene were observed in ten isolates of F. fujikuroi and F. verticillioides. With the exception of three isolates of F. fujikuroi, F. fujikuroi, F. proliferatum, and F. verticillioides were found to have FUM1 (the fumonisin biosynthetic gene); however, FUM1 was not found in isolates of F. concentricum. Results of pathogenicity testing showed that all isolates caused reduced germination of rice seed. In addition, F. fujikuroi and F. concentricum caused typical symptoms of bakanae, leaf elongation and chlorosis, whereas F. proliferatum and F. verticillioides only caused stunting of seedlings. These findings provide insight into the characteristics of GFSC associated with rice seeds and might be helpful in development of strategies for management of bakanae.

      • KCI등재

        제주도 고산 습지에서 분리한 Bacteroidetes, Firmicutes, Actinobacteria 문에 속하는 신종후보 세균

        최아영 ( Ah Young Choi ),최재희 ( Jae Hee Choi ),강지영 ( Ji Young Kang ),최정욱 ( Jeong Uk Choe ),이상훈 ( Sang Hoon Lee ),김하늘 ( Ha Neul Kim ),이하나 ( Ha Na Yi ),신영민 ( Young Min Shin ),장광엽 ( Kwang Yeop Jahng ),이현환 ( 한국환경생물학회 2011 환경생물 : 환경생물학회지 Vol.29 No.3

        Although Sumunmulbangdui wetland at the Halla Mountain in Jeju Island, a kind of montane wetlands, has been considered to bear high biodiversity, no study has been reported on the bacterial diversity. In this study, soil and water samples were collected from the wetland in order to isolate novel bacterial species. Bacterial strains belonging to the phyla Bacteroidetes, Firmicutes, and Actinobacteria were isolated after spreading soil and water samples onto solid agar media. The 16S rRNA gene sequences of the strains assigned to the three phyla were compared to those of type strains of the species in the phyla. The strains that showed less than 98.7% 16S rRNA gene sequence similarity to the validly published species were considered to be novel species candidates. A total of 32 strains were regarded as novel species candidates in the phyla Bacteroidetes, Firmicutes, and Actinobacteria. Diversity of novel species candidates was very low; the candidates were confined to only few genera. In the Bacteroidetes, 13 novel candidate species were affiliated with the genera Mucilaginibacter, Sphingobacterium, Pedobacter, Flavobacterium, and Chryseobacterium. A total of 13 novel candidate species that assigned to the genera Paenibacillus, Lysinibacillus, and Bacillus were identified in the phylum Firmicutes. Only two candidate species that belonged to the genera Mycobacterium and Nocardia were excavated in the Actinobacteria. Cultural, physiological, and chemotaxonomic characteristics have been determined for the novel species candidates, and the characteristics are described in this study.

      • KCI등재

        연근과 우절 에탄올 추출물의 향장효능 검증

        장영아(Young Ah Jang),박소현(So Hyun Park),김보애(Bo Ae Kim),박종이(Jong Yi Park),정영옥(Young Ok Jeoung),이진태(Jin Tae Lee) 한국유화학회 2017 한국응용과학기술학회지 Vol.34 No.3

        본 연구는 화장품 소재로서 연근과 우절의 가능성을 확인하기 위한 것이다. 이를 위해 우리는 연근과 우절 에탄올 추출물을 사용하여 항산화, 항염증 및 항주름에 대한 생물학적 활성 평가를 수행하였다. 연근과 우절을 95% 에탄올로 추출한 다음 항산화 평가를 위해 샘플을 농도 (100, 500, 1000) μg/mL 에 따라 처리하여 1,1-diphenyl-2-picrylhydrazyl (DPPH) 라디칼 소거능과 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) 양이온 라디칼 소거능을 확인하였다. 또한 항주름 효과를 평가하기 위해 Elastase 저해 활성 평가를 수행 하였다. 항염증 효과를 평가하기 위해서 대식세포 (Raw 264.7 cells)를 이용해 MTT assay를 통한 샘플의 독성평가와 nitric oxide 생성 저해 활성을 평가하였다. 그 결과 연근과 우절의 1000 μg/mL 농도에서 DPPH 라디칼 소거능 활성이 각 66.7%, 99.5% 로 ABTS+ 라디칼 소거능 활성은 동일농도에서 각 51.2%, 98.3%로 나타났다. elastase저해 활성 결과 우절이 연근에 비해 높은 항주름 효능을 나타내었다. 우절은 1000 μg/mL 농도에서 대조군 EGCG 보다 높은 활성을 나타내었다. Nitric oxide 저해 활성 결과에 따르면 연근은 55.8%의 효과를 나타내었고 우절은 66.6%의 효과를 각각 나타내어 우절 추출물이 연근보다 항염증 효과가 더 우수함을 나타내었다. 결과적으로 연근 및 우절 추출물은 안전한 항산화 항염증 및 항주름 천연화장품소재로 사용될 수 있음을 시사한다. This study is for checking the possibility of Lotus Rhizome and node of Lotus Rhizome as cosmetic materials. For this we carried out biological active evaluation about anti-oxidant, anti-inflammatory and anti-wrinkle by using ethanol extract of Lotus Rhizome and node of Lotus Rhizome. We extracted Lotus Rhizome and node of Lotus Rhizome with 95% ethanol and then in order to evaluate anti-oxidant activity we treated samples by concentrations (100, 500, 1000) μg/mL and carried out 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging and The activity of 2, 2’-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) cation radical scavenging. Also, in order to evaluate effect of anti-wrinkle we carried out evaluation of Elastase inhibitory activity. To evaluate effect of anti-inflammatory we evaluated toxicity of samples through MTT assay with a macrophage (Raw 264.7 cells) and measured nitric oxide production inhibitory activity. As a result, DPPH radical scavenging activity of Lotus Rhizome and node of Lotus Rhizome at 1000 μg/mL was 66.7% and 99.5%, respectively and ABTS + radical scavenging activity was 51.2% and 98.3% at the same concentration, respectively. Elastase inhibitory activity results showed that the nodes of the Lotus Rhizom extract excellent anti-wrinkle efficacy than Lotus Rhizom. Node of Lotus Rhizome showed higher anti-wrinkle activity than the positive the control group BHT at 1000 μg/mL concentration. According to the result of nitric oxide production inhibitory activity, Lotus Rhizom showed 55.8% effect and nodes of the Lotus Rhizom showed 66.6% effect respectively. This showed that effect of anti-inflammatory was greater in nodes of the Lotus Rhizom extracts. As a result it suggests that Lotus Rhizome and node of Lotus Rhizome extracts can be used as natural substance of cosmetics which are safe in antioxidant, anti-inflammatory, and anti-wrinkle.

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