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- 저자 : Yasushi Nakai (검색결과 2 건)
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Yasushi Nakai,Yusuke Iemura,Toshiteru Miyasaka,Shunta Hori,Makito Miyake,Nagaaki Marugami,Kiyohide Fujimoto,Nobumichi Tanaka 대한핵의학회 2022 핵의학 분자영상 Vol.56 No.5
Purpose This study evaluated the clinical utility of the highest bone scan index (BSI), among other BSIs, for each bone metastatic site in patients with bone metastatic castration–resistant prostate cancer (bmCRPC). Methods Thirty patients, diagnosed with bmCRPC by bone scintigraphy, were included. Total BSI, the number of hot spots, and regional BSI on each hot spot from bone scintigraphy at diagnosis with bmCRPC were evaluated by VSBONE BSI®. Highest regional BSI was defined as the highest value among regional BSIs on each hot spot in each patient. Related factors to overall survival and skeletal-related events (SREs) were evaluated using the Cox proportional-hazards model. Results The median follow-up time from diagnosis with bmCRPC was 29.0 months. During this time, 24 patients died, of which 22 patients died from prostate cancer. On univariate analysis, alkaline phosphatase (ALP) [Hazard ratio (HR): 5.96, 95% confidence interval (CI): 2.05–17.3] and highest regional BSI (HR: 2.01, 95% CI: 1.17–7.05) had significant correlation with overall survival. On multivariate analysis, ALP (HR: 4.79, 95% CI: 1.61–14.2) had significant correlation with overall survival. SREs were found in eight patients. Only the highest regional BSI (HR: 9.99, 95% CI: 2.46–40.6) significantly correlated with SREs on univariate analysis. Conclusion Highest regional BSI may provide important information regarding prognosis and SREs in patients with bmCRPC.
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A Proposal of Wheel/Rail Contact Model for Friction Control
Kosuke Matsumoto,Yoshihiro Suda,Hisanao Komine,Takuji Nakai,Masao Tomeoka,Kunihito Shimizu,Masuhisa Tanimoto,Yasushi Kishimoto,Takashi Fujii 대한기계학회 2005 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.19 No.1S
Controlling the friction between wheel and rail is direct and very effective measures to Improve the curving performances of railway trucks, because the curving performances depend much on friction characteristics Authors have proposed a method, "fllction control", which utilizes friction modifier (KELTRACKTM HPF) with onboard spraying system With the method, not only friction coefficient, but also fuction characteristics can be controlled as expected In this study, MBD simulation is very valuable tool to foresee the effect of the contiol In advance of experiment With real car And the creep characteristics of wheel/rail contact With the friction modifier takes very Important role In the simulation In this paper, authors propose a theoretical model of wheel/rat I contact condition considering the creep characteristics of friction modifier, Which is derived the application of principle tribological theories<br/>
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