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      • KCI등재

        Numerical Investigation on the Design and Optimization of Stacking Pattern for High Flexural Performance Carbon Fiber Reinforced Resin Matrix Composites

        Yao Cai,Xizhong An,Qingchuan Zou,Dengzhi Yao,Haitao Fu,Hao Zhang,Xiaohong Yang 한국섬유공학회 2022 Fibers and polymers Vol.23 No.9

        The stacking sequences of fiber-reinforced composites for optimization of turbine blades with the bestperformance have become a focus of attention. However, the optimization and design principles of its flexural performanceare not yet mature. Referring to the problems in previous work, a 3D finite element flexural model of carbon fiber reinforcedcomposites was established based on the Abaqus/Explicit VUMAT subroutine through the Tsai-Wu failure criterion. Theinfluencing laws and optimization mechanisms of different stacking patterns (e.g., different orientations, number oforientation plies, combination of multiple orientation plies, and symmetry/asymmetry structures) on the flexural properties ofthe composites were systematically investigated, and corresponding design references for the optimization of stackingpatterns were given. The results show that the smaller the value of |θ-45 °| (θ represents the angle of the orientation ply), themore obvious the stress reduction of the orientation ply, and the orientation ply located in the outer layer is more conducive tothe improvement of flexural performance. As the number of orientation plies increases, the flexural strength anddisplacement increase, but the stability decreases, in which the laminate with 50 % 0 ° orientation plies has the best overallperformance. In addition, the stability ranking of the laminate stacking sequences for the same 0 ° orientation ply proportionis: multi-orientation asymmetric > multi-orientation symmetric > single-orientation symmetric. In particular, the [75/02/60/30/02/15] laminate has the best overall performance with the flexural strength of 974 MPa and the Y-axis offset of 0.057 mm,and its stability is 66 % higher than that of the [15/02/75]S laminate. Under the same tensile/compressive stresses, the actualstress of the warp/weft in the orientation ply is less than the maximum ideal stress and the stress of Y-axis direction SY ≠ 0,which delays the fracture of the orientation ply and causes displacement offset, and the increase of the number of orientationplies will aggravate this effect. The obtained highlighted results can provide valuable references for the design andoptimization of stacking patterns of plain fabric-reinforced laminates with high flexural properties.

      • SCIESCOPUS

        A new approach for the cylindrical cavity expansion problem incorporating deformation dependent of intermediate principal stress

        Zou, Jin-Feng,Xia, Ming-yao Techno-Press 2017 Geomechanics & engineering Vol.12 No.3

        The problem of cylindrical cavity expansion incorporating deformation dependent of intermediate principal stress in rock or soil mass is investigated in the paper. Assumptions that the initial axial total strain is a non-zero constant and the axial plastic strain is not zero are defined to obtain the numerical solution of strain which incorporates deformation-dependent intermediate principal stress. The numerical solution of plastic strains are achieved by the 3-D plastic potential functions based on the M-C and generalized H-B failure criteria, respectively. The intermediate principal stress is derived with the Hook's law and plastic strains. Solution of limited expansion pressure, stress and strain during cylindrical cavity expanding are given and the corresponding calculation approaches are also presented, which the axial stress and strain are incorporated. Validation of the proposed approach is conducted by the published results.

      • SCOPUSKCI등재

        Application of Three-phase Hollow Fiber LPME using an Ionic Liquid as Supported Phase for Preconcentration of Malachite Green from Water Samples with HPLC Detection

        Zou, Yanmin,Zhang, Zhen,Shao, Xiaoling,Chen, Yao,Wu, Xiangyang,Yang, Liuqing,Zhu, Jingjing,Zhang, Dongmei Korean Chemical Society 2014 Bulletin of the Korean Chemical Society Vol.35 No.2

        A novel three-phase hollow fiber liquid phase microextraction was developed for the determination of malachite green (MG) in environmental waters, which selected [BMIM][$PF_6$] mixed with 1% trioctylphosphine oxide (TOPO) as supported phase. Several parameters (accepter phase pH, sample pH, supported phase membrane, volume of accepter phase, salinity, extraction time) that could affect extraction performance were investigated. Under the optimal extraction conditions, the established approach showed excellent characters as: high enrichment factor (212), wide linear range ($0.20-100{\mu}gL^{-1}$), low detection limit ($0.01{\mu}gL^{-1}$), good reproducibility (RSD, 8.9%, n=5) and satisfactory recovery (84.0-106.2%). The method was applied to detect MG at Yangtze River and pond waters in Zhenjiang, Jiangsu province, and 4 sites among 15 sampling sites were found MG with the concentration of $1.73-11.06{\mu}gL^{-1}$, which confirmed that the proposed environmentally friendly method was simple and effective for monitoring MG in aquatic system.

      • KCI등재

        Research Articles : The Influence of Challenge on Cathepsin B and D Expression Patterns in the Silkworm Bombyx mori L

        ( Feng Yao Wu ),( Feng Ming Zou ),( Jun Qiang Jia ),( Sheng Peng Wang ),( Guo Zheng Zhang ),( Xi Jie Guo ),( Zhong Zheng Gui ) 한국잠사학회 2011 International Journal of Industrial Entomology Vol.23 No.1

        Cathepsins are well-characterized proteases that are ubiquitously expressed in lysosomes. Previous work revealed that Bombyx mori cathepsins B and D are expressed in the fat body and undergo decomposition during larval-pupal metamorphosis. Quantitative RTPCR was performed to detect cathepsin gene expression at the transcription level when challenged by B. mori nuclear polyhedrosis virus (BmNPV), temperature and hormones (20-hydroxyecdysone (20E) and juvenile hormone analogue (JHA)). mRNAs encoding cathepsins B and D were significantly enhanced after the larvae were infected with BmNPV, and the peak of the induction appeared at 1 day before spinning. This attenuated the inducing effect on cathepsin expression caused by infection. Temperature shock induced cathepsin expression at the later stage of the 5th instar, and transcription levels varied with development stage and temperature. Cathepsin B and D mRNA expression in the fat body were significantly induced by JHA at the day before spinning, and with 20E, the expression reached a peak at the last day of the 5th instar. Cathepsin B and D mRNA expression exhibited detectable changes post-treatment, without significant differences between or among the hormone concentrations.

      • KCI등재

        Application of Three-phase Hollow Fiber LPME using an Ionic Liquid as Supported Phase for Preconcentration of Malachite Green from Water Samples with HPLC Detection

        Yanmin Zou,Zhen Zhang,Xiaoling Shao,Yao Chen,Xiangyang Wu,Liuqing Yang,Jingjing Zhu,Dongmei Zhang 대한화학회 2014 Bulletin of the Korean Chemical Society Vol.35 No.2

        A novel three-phase hollow fiber liquid phase microextraction was developed for the determination of malachite green (MG) in environmental waters, which selected [BMIM][PF6] mixed with 1% trioctylphosphine oxide (TOPO) as supported phase. Several parameters (accepter phase pH, sample pH, supported phase membrane, volume of accepter phase, salinity, extraction time) that could affect extraction performance were investigated. Under the optimal extraction conditions, the established approach showed excellent characters as: high enrichment factor (212), wide linear range (0.20-100 μg L-1), low detection limit (0.01 μg L-1), good reproducibility (RSD, 8.9%, n=5) and satisfactory recovery (84.0-106.2%). The method was applied to detect MG at Yangtze River and pond waters in Zhenjiang, Jiangsu province, and 4 sites among 15 sampling sites were found MG with the concentration of 1.73-11.06 μg L-1, which confirmed that the proposed environmentally friendly method was simple and effective for monitoring MG in aquatic system.

      • KCI등재

        Comparison of antibiotic resistance and copper tolerance of Enterococcus spp. and Lactobacillus spp. isolated from piglets before and after weaning

        Xueting Zou,Mengwei Weng,Xu Ji,Rong Guo,Weijiang Zheng,Wen Yao 한국미생물학회 2017 The journal of microbiology Vol.55 No.9

        In China, antimicrobials and copper are used extensively as growth-promoting agents for piglets. This study aimed to characterize the role of in-feed copper in the emergence of copper-tolerant and antibiotic-resistant Enterococcus and Lactobacillus isolates in Chinese pig farms. Feces of the same eight piglets from four litters at 7 and 55 days old and their mothers were traced in order to isolate Enterococcus spp. and Lactobacillus spp.. The minimum inhibitory concentrations of 10 antimicrobials and copper sulfate were determined using an agar dilution method. The feed levels of Cu2+ for lactating sows, suckling piglets, and weaned piglets were 6, 177, and 18 mg/kg, respectively. All the 136 Enterococcus isolates were sensitive to vancomycin; and the resistance rates to penicillin, enrofloxacin, and high level streptomycin resistance increased significantly after weaning. For the 155 Lactobacillus isolates, the resistance rates to ampicillin, chloramphenicol, tetracycline, and enrofloxacin were significantly higher in weaned piglets. The ratios of copper tolerant Enterococcus and Lactobacillus isolates both increased significantly after weaning (P < 0.05). A phenotypic correlation was observed after classifying the isolates into two groups (CuSO4 MIC50 < 16 or 16 for enterococci; CuSO4 MIC50 < 12 or 12 for lactobacilli) and comparing the antimicrobial-resistant percentage of two groups. On species level, a significant increase of E. faecalis to enrofloxacin was observed in line with the increase of copper MIC (P < 0.05). The findings revealed the changes of the antibiotic resistance and copper tolerance level of enterococci and lactobacilli between suckling and weaned piglets and demonstrated that there might be a strong association between in-feed copper and increased antibiotic resistance in enterococci and lactobacilli in Chinese intensive swine farms.

      • KCI등재

        A Novel Calibration Method Research of the Scale Factor for the All-optical Atomic Spin Inertial Measurement Device

        Sheng Zou,Xi-Yuan Chen,Hong Zhang,Yao Chen,Jian-cheng Fang 한국광학회 2015 Current Optics and Photonics Vol.19 No.4

        A novel method to measure the scale factor for the all-optical atomic spin inertial measurement device(ASIMD) is demonstrated in this paper. The method can realize the calibration of the scale factor by aself-consistent method with small errors in the quiescent state. At first, the matured IMU (inertialmeasurement unit) device was fixed on an optical platform together with the ASIMD, and it has beenused to calibrate the scale factor for the ASIMD. The results show that there were some errors causingthe inaccuracy of the experiment. By the comparative analysis of theory and experiment, the ASIMD wasunable to keep pace with the IMU. Considering the characteristics of the ASIMD, the mismatch betweenthe driven frequency of the optical platform and the bandwidth of the ASIMD was the major reason. Anall-optical atomic spin magnetometer was set up at first. The sensitivity of the magnetometer is ultra-high,and it can be used to detect the magnetization of spin-polarized noble gas. The gyromagnetic ratio ofthe noble gas is a physical constant, and it has already been measured accurately. So a novel calibrationmethod for scale factor based on the gyromagnetic ratio has been presented. The relevant theoreticalanalysis and experiments have been implemented. The results showed that the scale factor of the devicewas 7.272 V/°/s by multi-group experiments with the maximum error value 0.49%

      • A Survey of Loop Parallelization: Models, Approaches, and Recent Developments

        Hong Yao,Huifang Deng,Caifeng Zou 보안공학연구지원센터 2016 International Journal of Grid and Distributed Comp Vol.9 No.11

        In cloud computing era, automatic parallelization is still significant for virtualization platform. However, after several decades of development, the overall effect is still to be improved. Summary of the mainstream technology developments will be beneficial to reveal the future direction and trend. This paper reviews the technology of loop parallelization, which is the key issue in automatic parallelization. After introducing the basic models and approaches, we focus on the recent developments, on which we obtain the trend of this field and the conclusions about future.

      • KCI등재

        Dihydroartemisinin inhibits HepG2.2.15 proliferation by inducing cellular senescence and autophagy

        ( Jiang Zou ),( Qiang Ma ),( Ru Sun ),( Jiajing Cai ),( Hebin Liao ),( Lei Xu ),( Jingruo Xia ),( Guangcheng Huang ),( Lihua Yao ),( Yan Cai ),( Xiaowu Zhong ),( Xiaolan Guo ) 생화학분자생물학회(구 한국생화학분자생물학회) 2019 BMB Reports Vol.52 No.8

        Dihydroartemisinin (DHA) has been reported to possess anti-cancer activity against many cancers. However, the pharmacologic effect of DHA on HBV-positive hepatocellular carcinoma (HCC) remains unknown. Thus, the objective of the present study was to determine whether DHA could inhibit the proliferation of HepG2.2.15 cells and uncover the underlying mechanisms involved in the effect of DHA on HepG2.2.15 cells. We found that DHA effectively inhibited HepG2.2.15 HCC cell proliferation both in vivo and in vitro. DHA also reduced the migration and tumorigenicity capacity of HepG2.2.15 cells. Regarding the underlying mechanisms, results showed that DHA induced cellular senescence by up-regulating expression levels of proteins such as p-ATM, p-ATR, γ-H<sub>2</sub>AX, P53, and P21 involved in DNA damage response. DHA also induced autophagy (green LC3 puncta gathered together and LC3II/LC3I ratio increased through AKT-mTOR pathway suppression). Results also revealed that DHA-induced autophagy was not linked to senescence or cell death. TPP1 (telomere shelterin) overexpression could not rescue DHA-induced anticancer activity (cell proliferation). Moreover, DHA down-regulated TPP1 expression. Gene knockdown of TPP1 caused similar phenotypes and mechanisms as DHA induced phenotypes and mechanisms in HepG2.2.15 cells. These results demonstrate that DHA might inhibit HepG2.2.15 cells proliferation through inducing cellular senescence and autophagy. [BMB Reports 2019; 52(8): 520-525]

      • KCI등재

        On the Collapse Resistance of the Levy Type and the Loop-Free Suspen-Dome Structures After Accidental Failure of Cables

        Renjie Liu,Yao Zou,Guangyong Wang,Suduo Xue 한국강구조학회 2022 International Journal of Steel Structures Vol.22 No.2

        Current Levy type suspen-domes use loop cables which are key elements and carry large tensions. The loop-free suspendome was proposed for improving the collapse resistance and reducing cable tensions. However, the collapse resistance of the loop-free suspen-dome after accidental failure of cables has not been verifi ed and its key element is not clear. In this paper, analysis on the collapse resistance of both the Levy type suspen-dome and the loop-free suspen-dome after accidental failure of cables is performed based on the AP method by considering dynamic eff ect and non-linearity. The displacements and residual bearing capacity of 34 cable-rupture schemes are discussed, the eff ect on the cable tension and failure mode are also analyzed. It turns out that collapse resistance of the loop-free suspen-dome is better than the Levy type suspen-dome. The failure of cables does not infl uence the tension of remaining cables obviously so that the loop-free cable-strut system has suffi cient stiff ness and provides support and restraint for the reticulated shell. The most important cable in the loop-free suspen-dome is located in the outermost layer of the cable-strut system. It is also found that whether progressive collapse of the suspen-dome occurs after accidental failure of cables depends on both the bearing capacity of the reticulated shell and the residual contribution of the cable-strut system.

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