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      • KCI등재

        Effect of Nano-CaCO3 on the Sealing Efficiency of Grouts in Flowing Water Grouting

        Yao-Hui Liu,Ping Yang,Ze-Bin Ouyang,Xiao Wei,Lisha Zhang 대한토목학회 2020 KSCE JOURNAL OF CIVIL ENGINEERING Vol.24 No.10

        Flowing water grouting is a big challenge in the tunneling and underground engineering. To enhance the early strength and grouting effectiveness of slurry for flowing water grouting, nano-CaCO3 and fly ash were mixed with cement based grout. A series of physical simulation tests were conducted to simulate the flowing water grouting process in rough rock fracture, and investigate the effect of nano-CaCO3 content on the fluid pressure and sealing efficiency of grouts. Results of viscosity tests show that the viscosity of grouts decreased with an increase of nano-CaCO3 content. Scanning electron microscope (SEM) tests indicate that nano-CaCO3can promote the formation of fibrous hydrates and enhance the flowing water resistance of grouts. Increasing nano-CaCO3 content resulted in the first increase while later decrease of maximal fluid pressure (MFP) and sealing efficiency (SE) of grouts. Reducing water cement ratio of grouts and incorporating fly ash can effectively improve the SE of flowing water grouting.

      • KCI등재

        Optimization of helicon wave current drive in HL-2M tokamak

        Liu Hong Bo,Liu Guan Nan,Sun Ai Ping,Xiao Zheng Yao,Li Xin Xia 한국물리학회 2022 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.81 No.5

        Helicon waves have been proposed for efcient of-axis current drive in high-performance tokamaks. The HL-2M tokamak will be operated with high plasma beta approaching to 훽N ∼ 4.0%, which provides a good platform to apply helicon wave system in the machine. Based on the helicon wave dispersion relation, efects of electron Landau damping and transit time magnetic pumping on wave absorption are analyzed according to the HL-2M plasma, and then, an optimized scheme of helicon wave parameter is proposed. The evolution of helicon wave electric feld and produced current drive are calculated by the AORSA full-wave code. It shows that current drive efciency of 100 kA/MW can be generally received in the machine. Moreover, the AORSA results are actively benchmarked with the ray-tracing code, and the results show a good consistency. Finally, the numerical convergence and the consumption of computation resources on grid point numbers in AORSA code are discussed.

      • KCI등재

        Effect of Ion Source Current on the Microstructure and Properties of Cr-DLC Coatings Prepared by Ion Beam-Assisted Arc Ion Plating

        Yao Cai,Huidong Liu,Ye Ma,Qiang Wan,Hao Cheng,Yan Liu,Yanming Chen,Qingsong Mei,Bing Yang 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2017 NANO Vol.12 No.5

        Cr-containing diamond-like carbon (Cr-DLC) nanocomposite coatings were synthesized by ion beam-assisted arc ion plating with varying hollow cathode ion source (HCIS) currents. The morphologies, compositions and microstructures were characterized by scanning electronic microscopy (SEM), atomic force microscopy (AFM), X-Ray photoelectron spectrometer (XPS), Raman spectroscopy, grazing incidence X-ray diffraction (GIXRD) and high-resolution transmission electron microscopy (HRTEM). Hardness and friction coefficient were investigated by using nanoindentation and ball-on-disc tribometer, respectively. With no HCIS current, the coating exhibits the maximal growth rate and a rough surface, as well as lower hardness and elastic modulus. With the increasing HCIS current from 40 A to 80 A, the growth rate and the content of chromium carbide decrease obviously, the sp3/sp2 ratio increases initially to the maximum at the HCIS current of 60 A, the highest hardness and elastic modulus are obtained at the HCIS current of 50 A. It is also revealed that moderate HCIS current can reduce surface roughness obviously and promote tribological properties. The correlation of the HCIS current with the microstructure and performance of Cr-DLC coating has been established.

      • Synergism of Cytotoxicity Effects of Triptolide and Artesunate Combination Treatment in Pancreatic Cancer Cell Lines

        Liu, Yao,Cui, Yun-Fu Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.9

        Background: Triptolide, extracted from the herb Tripteryglum wilfordii Hook.f that has long been used as a natural medicine in China, has attracted much interest for its anti-cancer effects against some kinds of tumours in recent years. Artesunate, extracted from the Chinese herb Artemisia annua, has proven to be effective and safe as an anti-malarial drug that possesses anticancer potential. The present study attempted to clarify if triptolide enhances artesunate-induced cytotoxicity in pancreatic cancer cell lines in vitro and in vivo. Methods: In vitro, to test synergic actions, cell viability and apoptosis were analyzed after treatment of pancreatic cancer cell lines with the two agents singly or in combination. The molecular mechanisms of apoptotic effects were also explored using qRT-PCR and Western blotting. In vivo, a tumor xenograft model was established in nude mice, for assessment of inhibitory effects of triptolide and artesunate. Results: We could show that the combination of triptolide and artesunate could inhibit pancreatic cancer cell line growth, and induce apoptosis, accompanied by expression of HSP 20 and HSP 27, indicating important roles in the synergic effects. Moreover, tumor growth was decreased with triptolide and artesunate synergy. Conclusion: Our result indicated that triptolide and artesunate in combination at low concentrations can exert synergistic anti-tumor effects in pancreatic cancer cells with potential clinical applications.

      • The in vivo photothermal treatment of gold nanorod in the mouse ear model

        Liu, Bruce Yao Wen,Chen, Cheng-Lung,Lee, Shin-Yu,Chang, Fu-Hsiung,Lin, Win-Li,Chia, Chih-Ta,Chen, Yang-Yuan Techno-Press 2014 Biomaterials and Biomechanics in Bioengineering Vol.1 No.1

        Gold nanorod's exceptional light to heat transduction is a robust phonomenon that has been extensively verified. The phenomenon is a trait from which many novel applications across disciplines have been proposed. In this investigation, the feasibility of utilizing heat harvested from such photothermal method to combat cancer is presented. Using non-invasive laser methods, an in vivo study is conducted on mouse ear tumors administered with gold nanorods (Au NRs). An emphasis is placed on monitoring the tumor developments after photothermal treatments, over time. The findings reveal significant tumor growth surpression at a threshold laser power of $0.6W/cm^2$ lasting 2 minutes; this energy also brought about dramatic size reduction in treated tumors. Furthermore, the apparent formation of an eschar over the laser treated region indicates extensive hemorrhagic necrosis of the tumor tissue; a phenomenon implicative to the inhibition of angiogenesis.

      • KCI등재

        An Orthogonal Study of Industrial Scale Colour Fading Process of Cotton Fabric

        Yao-hui Liu,Chester Kin-Man To,Hiu-yan Cheung,Chi-wai Kan,Hong Chua 한국섬유공학회 2019 Fibers and polymers Vol.20 No.3

        Colour fading is now a popular process used for imparting a vintage look to textile and fashion products, whichenhances market value because of the current fashion trends. This study examined a non-aqueous colour fading process with the use of oxygen plasma-induced ozone treatment. An industrial scale machine and commercially available red sulpur-dyed cotton fabric (with 0.5 %, 1.5 % and 2.5 % colour depths) were used in this study. Since the colour fading process factors are inter-related to each other, a specific experiment approach, i.e. orthogonal method, was used for obtaining the optimum conditions in an industrial scale colour fading process. Three process factors used in the industrial scale colour fading process, i.e. (i) oxygen gas concentration (%); (ii) amount of water in fabric (%); and (iii) treatment time (minutes), would be studied in this paper. Through the orthogonal method, the optimum conditions for colour fading of the three colour depths of cotton fabric dyed by red sulphur dye were determined and their optimum conditions were same. The optimum conditions of the colour fading of the three colour depths were: (i) 70 % oxygen gas concentration; (ii) 35 % amount of water in fabric; and (iii) 30 minutes treatment time. Although colour fading conditions are the same, the order of importance of these process factors was different. Unlike the conventional colour fading process, oxygen plasma-induced ozone colour fading treatment can achieve uniform and even colour fading effect in the cotton fabric effectively.

      • KCI등재

        Management strategy for Spodoptera frugiperda (Lepidoptera:Noctuidae) in mountain maize planting areas in China

        Yao Yao,He Yanyan,Zhang Lilan,Wang Kun,Li Bin,Du Guangzu,Zhu Chunyue,Yi Xiaocui,Liu Yiyi,Zi Shengjiang,Chen Bin,Xiao Guanli 한국응용곤충학회 2023 Journal of Asia-Pacific Entomology Vol.26 No.4

        The fall armyworm, Spodoptera frugiperda (Lepidoptera: Noctuidae), is a major maize pest worldwide and has caused huge economic loss. To explore the control tactics of S. frugiperda in mountain maize planting fields, studies were performed in China from 2020 to 2021 for screening the S. frugiperda-resistant maize variety, seed coating agents, chemical insecticides, and biological agents. The results showed that 75 g/hm 2 Emamectin benzoate had better controlling efficacy (with a control efficacy of 91.05% at 1d) than other chemicals, so it was recommended in the high incidence period of pests. Compared with other seed coating treatments, 50% Lumi ngwei TM625FS (with a control efficacy of 76.19% at 10d) was the best seed coating against S. frugiperda. The biological control “Telenomus remus + Picromerus lewisi” and “T. remus + Eocanthecona furcellata” had good control efficacy on S. frugiperda with 76.01%, 64.10% at 20d, respectively. Additionally, there were lower numbers of S. frugiperda in maize variety GuiDan6, BaoYu9, and YanBaiYu8. In summary, this research rec ommended four effective pest management strategies (GuiDan6-resistant maize variety, 50% Lumingwei TM625FS-seed coating agents, 5% emamectin benzoate-chemical pesticide, and “T. remus + P. lewisi”-biological control) in mountain maize planting fields. The study provided effective control strategies for

      • The in vivo photothermal treatment of gold nanorod in the mouse ear model

        Liu, Bruce Yao Wen,Chen, Cheng-Lung,Lee, Shin-Yu,Chang, Fu-Hsiung,Lin, Win-Li,Chia, Chih-Ta,Chen, Yang-Yuan Techno-Press 2014 Biomaterials and biomedical engineering Vol.1 No.1

        Gold nanorod's exceptional light to heat transduction is a robust phonomenon that has been extensively verified. The phenomenon is a trait from which many novel applications across disciplines have been proposed. In this investigation, the feasibility of utilizing heat harvested from such photothermal method to combat cancer is presented. Using non-invasive laser methods, an in vivo study is conducted on mouse ear tumors administered with gold nanorods (Au NRs). An emphasis is placed on monitoring the tumor developments after photothermal treatments, over time. The findings reveal significant tumor growth surpression at a threshold laser power of $0.6W/cm^2$ lasting 2 minutes; this energy also brought about dramatic size reduction in treated tumors. Furthermore, the apparent formation of an eschar over the laser treated region indicates extensive hemorrhagic necrosis of the tumor tissue; a phenomenon implicative to the inhibition of angiogenesis.

      • Radio-Sensitization by Piper longumine of Human Breast Adenoma MDA-MB-231 Cells in Vitro

        Yao, Jian-Xin,Yao, Zhi-Feng,Li, Zhan-Feng,Liu, Yong-Biao Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.7

        Background: The current study investigated the effects of Piper longumine on radio-sensitization of human breast cancer MDA-MB-231 cells and underlying mechanisms. Materials and Methods: Human breast cancer MDA-MB-231 cells were cultured in vitro and those in logarithmic growth phase were selected for experiments divided into four groups: control, X-ray exposed, Piper longumine, and Piper longumine combined with X-rays. Conogenic assays were performed to determine the radio-sensitizing effects. Cell survival curves were fitted by single-hit multi-target model and then the survival fraction (SF), average lethal dose ($D_0$), quasi-threshold dose ($D_q$) and sensitive enhancement ratio (SER) were calculated. Cell apoptosis was analyzed by flow cytometry (FCM). Western blot assays were employed for expression of apoptosis-related proteins (Bc1-2 and Bax) after treatment with Piper longumine and/or X-ray radiation. The intracellular reactive oxygen species (ROS) level was detected by FCM with a DCFH-DA probe. Results: The cloning formation capacity was decreased in the group of piperlongumine plus radiation, which displayed the values of SF2, D0, Dq significantly lower than those of radiation alone group and the sensitive enhancement ratio (SER) of D0 was1.22 and 1.29, respectively. The cell apoptosis rate was increased by the combination treatment of Piper longumine and radiation. Piper longumine increased the radiation-induced intracellular levels of ROS. Compared with the control group and individual group, the combination group demonstrated significantly decreased expression of Bcl-2 with increased Bax. Conclusions: Piper longumine at a non-cytotoxic concentration can enhance the radio-sensitivity of MDA-MB-231cells, which may be related to its regulation of apoptosis-related protein expression and the increase of intracellular ROS level, thus increasing radiation-induced apoptosis.

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