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        Safety and efficacy of 3D-printed templates assisted CT-guided radioactive iodine-125 seed implantation for the treatment of recurrent cervical carcinoma after external beam radiotherapy

        Yanhao Liu,Ping Jiang,Haichen Zhang,Junjie Wang 대한부인종양학회 2021 Journal of Gynecologic Oncology Vol.32 No.2

        Objective: To investigate the safety and efficacy of 3-dimensional (3D) printing non coplanar templates (PNCT) assisted computer tomography (CT) guided radioactive 125I seedimplantation (RISI) for the treatment of recurrent cervical carcinoma (RCC) after externalbeam radiotherapy (EBRT). Methods: A total of 103 patients with inoperable post-EBRT RCC were included in thisretrospective study. A total of 111 lesions received RISI. Eight lesions were at the pelvic center,75 lesions were at the pelvic lateral, and 28 lesions were extra-pelvic metastasis. The medianprescription dose was 120 Gy. The primary end points were adverse events and local control(LC), and the secondary end points were overall survival (OS) and progression-free survival. Results: Grade 2 adverse events of acute nausea, diarrhea, and pollakiuria occurred in 1, 2,and 1 patient, respectively. One patient suffered from grade 3 acute proctitis. Late toxicitywas observed in 2 patients with rectovaginal fistula. No grade 5 toxicity occurred. The 3-yearLC and OS rates were 75.1% and 20.8%, respectively. The median OS was 17 months. Themultivariate analysis showed that the minimum dose received by the “hottest” 90% of thegross tumor volume (D90) ≥130 Gy, squamous cell carcinoma, hemoglobin ≥80 g/L and goodshort-term efficacy (complete response or partial response) were independent predictors ofLC and OS (all p<0.05). Conclusions: 3D-PNCT assisted CT-guided RISI is a safe, effective, and minimally invasivemodality for RCC. The hemoglobin level, pathological type, dose distribution and short-termefficacy are considered as independent factors for clinical outcomes.

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        Research on Magnetic Actuation Mechanism and Kinematics of Soft Inspection Robot for HVDC Transmission Line

        Xianjin Xu,Yanhao Huang,Lanlan Liu,Yu Yan,Haifeng Yan,Yuhang Yang 한국자기학회 2023 Journal of Magnetics Vol.28 No.2

        Currently, most of the inspection robots for high-voltage transmission lines, both at home and abroad, utilize a multi-cantilever rigid structure. However, the inefficiency and poor safety of these robots when it comes to crossing obstacles make them impractical. To address this issue, a magnetically actuated soft inspection robot has been developed. This robot uses the amperage force applied to the current-carrying coil in a HVDC toroidal magnetic field to efficiently and flexibly cross multiple obstacles in an inchworm-like motion. The focus of this paper is on the design and theoretical calculation of the magnetically actuated model, specifically the magnetic linear traction force and magnetic adsorption force (diastolic force), required to enable the soft robot to crawl. Through simulation and kinematic analysis, the results show that the magnetically actuated soft robot design proposed in this paper is theoretically feasible, providing a foundation for future developments in magnetically actuated soft robots.

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