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Paola A. Escalante Abril,Miguel Fdo. Salazar,Nubia L. López García,Mónica N. Madrazo Moya,Yadir U. Zamora Guerra,Yadira Gandhi Mata Mendoza,Erick Gómez Apo,Laura G. Chávez Macías 대한병리학회 2015 Journal of Pathology and Translational Medicine Vol.49 No.6
We report a 50-year-old woman with no relevant clinical history who presented with headache and loss of memory. Magnetic resonance imaging showed a left parieto-temporal mass with annular enhancement after contrast media administration, rendering a radiological diagnosis of high-grade astrocytic neoplasm. Tumour sampling was performed but the patient ultimately died as a result of disease. Microscopically, the lesion had areas of glioblastoma mixed with a benign mesenchymal constituent; the former showed hypercellularity, endothelial proliferation, high mitotic activity and necrosis, while the latter showed fascicles of long spindle cells surrounded by collagen and reticulin fibers. With approximately 40 previously reported cases, gliofibroma is a rare neoplasm defined as either glio-desmoplastic or glial/benign mesenchymal. As shown in our case, its prognosis is apparently determined by the degree of anaplasia of the glial component.
Miguel Fdo. Salazar,Paola A. Escalante Abril,Nubia L. López García,Mónica N. Madrazo Moya,Yadir U. Zamora Guerra,Yadira Gandhi Mata Mendoza,Erick Gómez Apo,Laura G. Chávez Macías 대한병리학회 2015 Journal of Pathology and Translational Medicine Vol.49 No.4
We report a 50-year-old woman with no relevant clinical history who presented with headache and loss of memory. Magnetic resonance imaging showed a left parieto-temporal mass with annular enhancement after contrast media administration, rendering a radiological diagnosis of high-grade astrocytic neoplasm. Tumour sampling was performed but the patient ultimately died as a result of disease. Microscopically, the lesion had areas of glioblastoma mixed with a benign mesenchymal constituent; the former showed hypercellularity, endothelial proliferation, high mitotic activity and necrosis, while the latter showed fascicles of long spindle cells surrounded by collagen and reticulin fibers. With approximately 40 previously reported cases, gliofibroma is a rare neoplasm defined as either glio-desmoplastic or glial/benign mesenchymal. As shown in our case, its prognosis is apparently determined by the degree of anaplasia of the glial component.
Simulation of the Electrical Resistance Sintering of Hardmetal Powders
Juan Manuel Montes,Francisco J. de la Viña,Íñigo Agote,Thomas Schubert,Francisco G. Cuevas,Yadir Torres,José María Gallardo,Jesús Cintas 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.2
The simulation of the electrical resistance sintering (ERS) of hardmetal powders has been studied. The ERS process canproduce a quick consolidation of electrical conductive powders by the simultaneous application of pressure and electricalcurrent. A model of the process has been developed, integrating three actions, namely, thermal, mechanical and electrical,and taking into account the nature of both the powders and the die where powders are placed. The model has been implementedin COMSOL Multiphysics, a finite element commercial program. This paper deals with the model fundamentals andhardmetal particular aspects, such as modelling properties of mixed powders and its thermal behaviour. Other parameters inthe model have been tuned to optimally fit the initial experimental data. To check simulation results, measurable parametershave been monitored during experimental tests with WC–6 wt% Co. Once the model was completed and put to work, resultsare discussed.