MicroRNA-138 Suppresses Adipogenic Differentiation in Human Adipose Tissue-Derived Mesenchymal Stem Cells by Targeting Lipoprotein Lipase

Yuting Wang,Lixin Lin,Yong Huang,Junjun Sun,Xueming Wang,Peng Wang 연세대학교의과대학 2019 Yonsei medical journal Vol.60 No.12

Purpose: Adipogenic differentiation of adipose tissue-derived mesenchymal stem cells (AMSCs) is critical to many disease-relateddisorders, such as obesity and diabetes. Studies have demonstrated that miRNA-138 (miR-138) is closely involved in adipogenesis. However, the mechanisms affected by miR-138 remain unclear. This work aimed to investigate interactions between miR-138and lipoprotein lipase (LPL), a key lipogenic enzyme, in AMSCs. Materials and Methods: Human AMSCs (hAMSCs) isolated from human abdomen tissue were subjected to adipogenic differentiationmedium. Quantitative real-time polymerase chain reaction and Western blot assay were applied to measure the expressionsof miR-138, LPL, and the two adipogenic transcription factors cytidine-cytidine-adenosine-adenosine-thymidine enhancerbinding protein alpha (C/EBPα) and peroxisome proliferator-activated receptor gamma (PPARγ). The relationship between miR-138 and LPL was predicted utilizing the miRTarBase database and validated by dual luciferase reporter assay. Results: Showing increases in C/EBPα and PPARγ expression levels, hAMSCs were induced into adipogenic differentiation. Duringadipogenesis of hAMSCs, miR-138 expression was significantly downregulated. Overexpression of miR-138 by transfection inhibitedhAMSCs adipogenic differentiation in vitro. Mechanically, LPL was a target of miR-138. LPL expression was upregulated duringadipogenesis of hAMSCs, and this upregulation was reversed by miR-138 overexpression. Functionally, silencing of LPL by transfectionexerted similar inhibition of the expressions of C/EBPα and PPARγ. Meanwhile, LPL ectopic expression was able to partlyabolish the suppressive effect of miR-138 overexpression on adipogenic differentiation of hAMSCs. Conclusion: Upregulation of miR-138 inhibits adipogenic differentiation of hAMSCs by directly downregulating LPL.

UV-crosslinked Solution Blown PVDF Nanofiber Mats for Protective Applications

Ya Liu,Xueming Wang,Nana Li,Xiaoyin Wang,Lei Shi,Enjie Wu,Rui Wang,Mingjing Shan,Xupin Zhuang 한국섬유공학회 2020 Fibers and polymers Vol.21 No.3

Nanofiber mats have received considerable attention from researchers in the field of particulate protection. In thisstudy, polyvinylidene fluoride (PVDF) nanofiber mats were prepared on a large scale by a solution blowing process, and thencrosslinked by ultraviolet (UV)-radiation using trimethylolpropane tri-acrylate (TMPTA) as a crosslinker. The structure,morphology, mechanical and thermal properties, and protective performance of the nanofiber mats were evaluated. Resultsshow that the addition of TMPTA and UV treatment decreased the diameter of the nanofibers and enhanced the mechanicalproperties, air permeability, and moisture permeability. Nanofiber mats show higher filtration and lower filtration resistancecompared with a commercial product. Furthermore, the nanofiber mats were bonded with Nylon 6 fabric, which showedgood performance as a novel functional layer in protective clothing.

Left quasi-abundant semigroups

Zhulin Ji,Xueming Ren,Yanhui Wang 대한수학회 2019 대한수학회지 Vol.56 No.5

A semigroup $S$ is called a weakly abundant semigroup if its every $\widetilde{\mathcal{L}}$-class and every $\widetilde{\mathcal{R}}$-class contains an idempotent. Our purpose is to study an analogue of orthodox semigroups in the class of weakly abundant semigroups. Such an analogue is called a left quasi-abundant semigroup, which is a weakly abundant semigroup with a left quasi-normal band of idempotents and having the congruence condition (C). To build our main structure theorem for left quasi-abundant semigroups, we first give a sufficient and necessary condition of the idempotent set $E(S)$ of a weakly abundant semigroup $S$ being a left quasi-normal band. And then we construct a left quasi-abundant semigroup in terms of weak spined products. Such a result is a generalisation of that of Guo and Shum for left semi-perfect abundant semigroups. In addition, we consider a type $Q$ semigroup which is a left quasi-abundant semigroup having the PC condition.

A Distributed Implementation Algorithm for Physical Layer Security Based on Untrusted Relay Cooperation and Artificial Noise

Xiangyu Li,Xueming Wang,Xiangyang Xu,Liang Jin 한국전자통신연구원 2014 ETRI Journal Vol.36 No.1

In this letter, we consider a cooperation system with multipleuntrusted relays (URs). To keep the transmitted informationconfidential, we obtain joint channel characteristics (JCCs)through combining the channels from the source to thedestination. Then, in the null space of the JCCs, jammersconstruct artificial noise to confuse URs when the source nodebroadcasts its data. Through a distributed implementationalgorithm, the weight of each node can be obtained from itsown channel state information. Simulation results show thathigh-level security of the system can be achieved when internaland external eavesdroppers coexist.

Tellurium-enhanced nonresonant third-order optical nonlinearity in a germanosilicate optical fiber.

Lin, Aoxiang,Liu, Xueming,Watekar, Pramod R,Zhao, Wei,Peng, Bo,Lu, Min,Wei, Wei,Sun, Chuandong,Wang, Yishan,Han, Won-Taek,Toulouse, Jean Optical Society of America 2009 Applied Optics Vol.48 No.26

<P>A tellurium-doped germanosilicate optical fiber was developed by modified chemical vapor deposition and solution doping techniques. Using the continuous-wave self-phase modulation method, the nonresonant nonlinear refractive index, n2, was measured to be 5.52 x 10(-20) m2/W, which is 2 to 3 times that of the undoped germanosilicate glass fiber. Polyhedron structures TeO3 and TeO4 with GeO4 and SiO4 are believed responsible for lower phonon energy, more nonbridging oxygens, and a larger hyperpolarization, leading to the observed higher nonresonant optical nonlinearity.</P>

Efficient Regulation of Dyeing Behavior and Physical Properties of Bombyx mori Silks via Graft Polymerization of α-Lipoic Acid

Leilei Wu,Yiwen Ren,Xueming Bao,Ping Wang,Man Zhou,Man Zhou,Qiang Wang 한국섬유공학회 2022 Fibers and polymers Vol.23 No.8

Generally, Bombyx mori silk dyeing is performed using acid dyes. However, the color fastness is alwaysunsatisfactory due to the weak binding forces under neutral conditions. In the present work, graft polymerization of α-lipoicacid (ALA) onto silk fibers was carried out using a two-step method. Briefly, ALA was grafted onto the silk fibers, followedby a reduction-oxidation process to form poly(α-lipoic acid) (PALA) on the fiber surfaces, aiming at improving theelectronegativity of fiber surface and realizing cationic dyeing. The results implied that the combined treatments promotedthe intermolecular crosslinking between fibroin chains, endowing the silk fiber with low zeta potential simultaneously. A thinsedimentary layer on the fiber surfaces was observed for the PALA-deposited silk fibers, companying with a significantincrease in the content of sulfur and O/N ratio, which verified the successful graft polymerization. The modified silk fabricexhibited improved dyeability, and the dyeing depth and color fastness was noticeably higher compared to that of theuntreated after cationic dyeing. Meanwhile, the newly-built intermolecular disulfide crosslinks imparted a detectable antiwrinkleeffect to the silk fabric. This study provides a facile strategy for modification of silk fabric with improved dyeingbehaviors and physical properties.

LEFT QUASI-ABUNDANT SEMIGROUPS

Ji, Zhulin,Ren, Xueming,Wang, Yanhui Korean Mathematical Society 2019 대한수학회지 Vol.56 No.5

A semigroup S is called a weakly abundant semigroup if its every $\tilde{\mathcal{L}}$-class and every $\tilde{\mathcal{R}}$-class contains an idempotent. Our purpose is to study an analogue of orthodox semigroups in the class of weakly abundant semigroups. Such an analogue is called a left quasi-abundant semigroup, which is a weakly abundant semigroup with a left quasi-normal band of idempotents and having the congruence condition (C). To build our main structure theorem for left quasi-abundant semigroups, we first give a sufficient and necessary condition of the idempotent set E(S) of a weakly abundant semigroup S being a left quasi-normal band. And then we construct a left quasi-abundant semigroup in terms of weak spined products. Such a result is a generalisation of that of Guo and Shum for left semi-perfect abundant semigroups. In addition, we consider a type Q semigroup which is a left quasi-abundant semigroup having the PC condition.

STUDY OF MULTILAYER STRUCTURE USING X-RAY DOUBLE CRYSTAL DIFFRACTION

Wu, Yunzhong,Xu, Xueming,Wang, Weiyuan The Korean Vacuum Society 1995 Applied Science and Convergence Technology Vol.4 No.s2

By using X-ray double crystal diffraction technique the multilayer structure composed of glass membrane, platinum film and $\alpha Al_2O_3$ substrate has been studied. It is found the stress is produced in the film by thermal mismatch within multilayer materials. The measuring results of thin film platinum resistors show that the stress were induce resistance change of device and different stress status will produce add resistance in different direction. Selecting proper glass material can make opposite stress in Pt film and opposite add resistance due to thermal mismatch. The reliability of Pt resistor has been improved with method of this stress compensation.

Weighted Average Consensus of Second-order Multi-agent Systems with Various Intelligence Levels via Sampled-data Control

Jinhui Zeng,Pin Wang,Zheng Lan,Xueming Luo,Jianghong Li,Jiaxi Hu 제어·로봇·시스템학회 2023 International Journal of Control, Automation, and Vol.21 No.5

In this paper, weighted average consensus of second-order multi-agent systems (MASs) via sampleddata control is investigated. Specially, since the intelligence degree of each agent may be different in practical applications, the concept of intelligence level is introduced to characterize the intelligence degrees of agents in this paper. A novel distributed continuous-time control protocol with various intelligence levels is put forward based on sampled data in order to reduce the updating rates and computational burden of the controller. A necessary and sufficient condition is derived to achieve weighted average consensus under the proposed protocol. Moreover, according to the acquired result, the authors also give the choosing approaches of the feedback gains and sampling period. Finally, several numerical simulations are provided to illustrate the reliability of the theoretical results.

Joint Fingerprinting and Encryption in the DWT Domain for Secure M2M Communication

Conghuan Ye,Zenggang Xiong,Yaoming Ding,Xueming Zhang,Guangwei Wang,Fang Xu 보안공학연구지원센터 2016 International Journal of Security and Its Applicat Vol.10 No.1

Machine-to-machine (M2M) communication is viewed as one of the next frontiers in wireless communications. Because of unguarded communication, new security threats emerge. Considering that multimedia will be widely used in various applications over M2M network, it is very urgent to meet new security requirements for multimedia communication. This paper focuses on a joint fingerprinting and encryption (JFE) scheme in the DWT domain with the purpose of protecting multimedia distribution. A multimedia encryption scheme is first to scramble the multimedia content before distribution, and the fingerprinting scheme is then introduced to provide further protection. The goal of the proposed content distribution scheme is to provide secure content communication and deter the device from illegally redistributing the content. The proposed method, to the best of our knowledge, is the first JFE method in the DWT domain for secure M2M communication. The use of fingerprinting along with encryption can provide a double-layer of protection to digital media. Theory analysis and experimental results show the effectiveness of the proposed scheme.