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RISS 인기검색어
- 검색키워드
- 저자 : Xiangpeng Yue (검색결과 4 건)
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Xie, Xiangpeng,Yue, Dong,Park, Ju H.,Li, Hongyi IEEE 2018 IEEE transactions on fuzzy systems Vol.26 No.5
<P>This paper deals with more relaxed designs of discrete-time Takagi–Sugeno fuzzy-model-based observers via two effective technical measures. Different from previous methods of this field, two effective technical measures are developed for obtaining more relaxed results, i.e., 1) A novel ranking-based switching mechanism is proposed by introducing a set of weighted variables so as to make use of the size differences information among normalized fuzzy weighting functions more freely. 2) A new slack variable method is proposed via the introduction of some extended representations for homogenous polynomials, and those major and minor relationships among all normalized fuzzy weighting functions are mapped to sole augmented multiindexed matrix for each homogeneous polynomial. Therefore, two positive results are provided in this paper, i.e., less conservative fuzzy observers can be given as a result of the above effective measures whilst a part of the online computational cost can be transferred to the offline implementation. Finally, two numerical examples are applied to illustrate the effectiveness of our approach.</P>
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Gallic acid caused cultured mice TM4 Sertoli cells apoptosis and necrosis
Wanhong Li,Xiangpeng Yue,Fadi Li 아세아·태평양축산학회 2019 Animal Bioscience Vol.32 No.5
Objective: The study was designed to determine the cytotoxic effect of gallic acid (GA), obtained by the hydrolysis of tannins, on mice TM4 Sertoli cells apoptosis. Methods: In the present study, non-tumorigenic mice TM4 Sertoli cells were treated with different concentrations of GA for 24 h. After treatment, cell viability was evaluated using WST-1, mitochondrial dysfunction, cells apoptosis and necrosis was detected using JC-1, Hoechst 33342 and propidium iodide staining. The expression levels of Cyclin B1, proliferating cell nuclear antigen (PCNA), Bcl-2-associated X protein (BAX), and Caspase-3 were also detected by quantitative real-time polymerase chain reaction and Western-blotting. Results: The results showed that 20 to 400 μM GA inhibited viability of TM4 Sertoli cells in a dose-dependent manner. Treatment with 400 μM GA significantly inhibited PCNA and Cyclin B1 expression, however up-regulated BAX and Caspase-3 expression, caused mitochondrial membrane depolarization, activated Caspase-3, and induced DNA damage, thus, markedly increased the numbers of dead cells. Conclusion: Our findings showed that GA could disrupt mitochondrial function and caused TM4 cells to undergo apoptosis and necrosis.
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Y-Single Nucleotide Polymorphisms Diversity in Chinese Indigenous Horse
Han, Haoyuan,Zhang, Qin,Gao, Kexin,Yue, Xiangpeng,Zhang, Tao,Dang, Ruihua,Lan, Xianyong,Chen, Hong,Lei, Chuzhao Asian Australasian Association of Animal Productio 2015 Animal Bioscience Vol.28 No.8
In contrast to high genetic diversity of mitochondrial DNA (mtDNA), equine Y chromosome shows extremely low variability, implying limited patrilines in the domesticated horse. In this study, we applied direct sequencing and restriction fragment length polymorphism (RFLP) methods to investigate the polymorphisms of 33 Y chromosome specific loci in 304 Chinese indigenous horses from 13 breeds. Consequently, two Y-single nucleotide polymorphisms (SNPs) (Y-45701/997 and Y-50869) and one Y-indel (Y-45288) were identified. Of those, the Y-50869 (T>A) revealed the highest variation frequency (24.67%), whereas it was only 3.29% and 1.97% in Y-45288 (T/-) and Y-45701/997 (G>T) locus, respectively. These three mutations accounted for 27.96% of the total samples and identified five Y-SNP haplotypes, demonstrating genetic diversity of Y chromosome in Chinese horses. In addition, all the five YSNP haplotypes were shared by different breeds. Among 13 horse breeds analyzed, Balikun horse displayed the highest nucleotide diversity (${\pi}=5.6{\times}10^{-4}$) and haplotype diversity (h = 0.527), while Ningqiang horse showed the lowest nucleotide diversity (${\pi}=0.00000$) and haplotype diversity (h = 0.000). The results also revealed that Chinese horses had a different polymorphic pattern of Y chromosome from European and American horses. In conclusion, Chinese horses revealed genetic diversity of Y chromosome, however more efforts should be made to better understand the domestication and paternal origin of Chinese indigenous horses.
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Y-Single Nucleotide Polymorphisms Diversity in Chinese Indigenous Horse
Haoyuan Han,Qin Zhang,Kexin Gao,Xiangpeng Yue,Tao Zhang,Rui-Hua Dang,Xianyong Lan,Hong Chen,Chuzhao Lei 아세아·태평양축산학회 2015 Animal Bioscience Vol.28 No.8
In contrast to high genetic diversity of mitochondrial DNA (mtDNA), equine Y chromosome shows extremely low variability, implying limited patrilines in the domesticated horse. In this study, we applied direct sequencing and restriction fragment length polymorphism (RFLP) methods to investigate the polymorphisms of 33 Y chromosome specific loci in 304 Chinese indigenous horses from 13 breeds. Consequently, two Y-single nucleotide polymorphisms (SNPs) (Y-45701/997 and Y-50869) and one Y-indel (Y-45288) were identified. Of those, the Y-50869 (T>A) revealed the highest variation frequency (24.67%), whereas it was only 3.29% and 1.97% in Y-45288 (T/-) and Y-45701/997 (G>T) locus, respectively. These three mutations accounted for 27.96% of the total samples and identified five Y-SNP haplotypes, demonstrating genetic diversity of Y chromosome in Chinese horses. In addition, all the five Y-SNP haplotypes were shared by different breeds. Among 13 horse breeds analyzed, Balikun horse displayed the highest nucleotide diversity (π = 5.6×10‒4) and haplotype diversity (h = 0.527), while Ningqiang horse showed the lowest nucleotide diversity (π = 0.00000) and haplotype diversity (h = 0.000). The results also revealed that Chinese horses had a different polymorphic pattern of Y chromosome from European and American horses. In conclusion, Chinese horses revealed genetic diversity of Y chromosome, however more efforts should be made to better understand the domestication and paternal origin of Chinese indigenous horses.
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