http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Li Ming,Yin Liming,Wu Lili,Zhu Yunsen,Wang Xi 대한독성 유전단백체 학회 2020 Molecular & cellular toxicology Vol.16 No.4
Background Paclitaxel is a chemotherapeutic drug for cancer, which is isolated from the Pacifc yew tree. However, and the molecular mechanism and the antitumor efects of paclitaxel on osteosarcoma cell remain to be explored. Objective The aim of our study was to explore the possible molecular mechanisms of apoptosis in osteosarcoma induced by paclitaxel. Results Paclitaxel can obviously decrease the proliferation of HOS-732 cells in a dose-dependent manner. Paclitaxel could induce the cell cycle arrest at the G2/M-phase and decreases the CDK5 and CCNE1 expression in HOS-732 cells. Paclitaxel promotes cell apoptosis in HOS-732 cells, which may be contacted to the decreasing of Bcl-2 protein expression. Further, the production of ROS in HOS-732 cells was remarkably increased with the increasing concentration of paclitaxel. Moreover, paclitaxel induces the ER-stress related gene and protein expression (GRP79, DDIT3 mRNA and GRP78, XBP-1 s, IRE1α protein expression) in osteosarcoma cells. Conclusion Paclitaxel can inhibit the proliferation of HOS-732 cells and increase ROS and ER-stress response to promote cell apoptosis, suggesting that paclitaxel may represent a new therapeutic option for the treatment and prevention osteosarcoma.
( Wenlan Wu ),( Xianbin Wen ),( Haixia Xu ),( Liming Yuan ),( Qingxia Meng ) 한국인터넷정보학회 2018 KSII Transactions on Internet and Information Syst Vol.12 No.3
This paper presents a novel range-free localization algorithm based on quantum particle swarm optimization. The proposed algorithm is capable of estimating the distance between two non-neighboring sensors for multi-hop heterogeneous wireless sensor networks where all nodes’ communication ranges are different. Firstly, we construct a new cumulative distribution function of expected hop progress for sensor nodes with different transmission capability. Then, the distance between any two nodes can be computed accurately and effectively by deriving the mathematical expectation of cumulative distribution function. Finally, quantum particle swarm optimization algorithm is used to improve the positioning accuracy. Simulation results show that the proposed algorithm is superior in the localization accuracy and efficiency when used in random and uniform placement of nodes for heterogeneous wireless sensor networks.
Yiling Zheng,Liming Wang,Fan Wu,Weiqi Rong,Yunhe Liu,Kai Zhang,Jianxiong Wu 대한외과학회 2020 Annals of Surgical Treatment and Research(ASRT) Vol.98 No.5
Purpose: To evaluate the safety and effectiveness of an enhanced recovery after surgery (ERAS) programme after curative liver resection in cirrhotic hepatocellular carcinoma (HCC) patients. Methods: One hundred sixty-two patients were enrolled in the study; 80 patients whose data were collected prospectively were assigned to the ERAS group, and 82 patients whose data were collected retrospectively were assigned to the control group. Preoperative clinicopathologic factors, surgical factors, and postoperative outcomes of the 2 groups were compared. Logistic regression was applied to explore potential predictors of hospital stay and morbidity. Results: The postoperative hospital stay, postoperative complication rate, and recovery of liver function on postoperative day 5 seemed to be better in the ERAS group. The composition of complications was different in the 2 groups; pleural effusion and postoperative ascites were more common in the control group, and indocyanine green retention at 15 minutes, operation time, preoperative alanine aminotransferase, and number of liver segmentectomies were associated with postoperative complications rather than ERAS intervention. Conclusion: The ERAS programme is safe and effective for HCC patients with chronic liver disease undergoing hepatectomy, but it seems that surgical factors, such as operation type, have a greater impact on morbidity than other factors. Operative characteristics such as the method of blood loss control and the volume of liver resection should be augmented into ERAS protocol of hepatectomy.
Error Analysis of Multidimensional Evaluation of Pilot’s Workload Based on Objective Measures
Chan Wei,Liming Wei,Zhengxiang Cai,Yanyu Lu,Qi Wu,Dan Huang,Shan Fu 제어로봇시스템학회 2015 제어로봇시스템학회 국제학술대회 논문집 Vol.2015 No.10
Evaluation of pilot’s workload during flight is a significant consideration for the safety of civil aviation. However, some errors may be brought in the measurement and the recording of objective parameters. Based on a multidimensional workload evaluation, the time delay of cardiac activity and its impacts on workload are analyzed. The results suggest that within a certain limit of error around 10s, varying from individual to individual, workload can keep the main information compared to the original workload. As the error increases, the workload may become unreliable. As a consequence, the time-delay error of cardiac activity should be controlled in a limited scale to ensure the validity and reliability of workload.
Study on the combustion process and work capacity of a micro free-piston engine
Qian Wang,Liming Dai,Kai Wu,Jin Bai,Zhixia He 대한기계학회 2015 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.29 No.11
With the main idea of exploring combustion conditions and the work capacity of the micro free-piston engine, the study concern isvisualization work including Homogeneous charge compression ignition (HCCI) combustion in the micro-chamber. The initial freepistonvelocity was adjusted to achieve a wide range of compression ratio. The combustion characteristics, the piston motion and pressurevariations under different compression ratios were discussed. Results indicate that the critical combustion condition occurs when thecompression ratio rises to a certain degree. Two-stage combustion characteristics can be observed in micro HCCI combustion processeswith the fuel of the DME/oxygen mixture. The micro-chamber pressure increases with the increase of the compression ratio. The criticalpeak pressure of 5.4 MPa is obtained when the initial piston velocity reaches 15.0 m/s and the diameter and the length of the microchamberis 3 mm and 37 mm, respectively.
Liu, Chune,Wu, Lele,Xue, Ying,Liu, Feng,Sun, Shan,Wang, Liming 한국식품과학회 2018 Food Science and Biotechnology Vol.27 No.3
In this study, the total concentration and bioaccessibility of four metals (Zn, Se, Cd, Cu) in sea cucumbers (Apostichopus japonicus) before and after cooking were measured. The concentration of Zn, Se, Cd, and Cu were $22.24{\pm}0.75$, $0.75{\pm}0.06$, $0.32{\pm}0.07$, and $1.88{\pm}0.09mg/kg$ in raw cucumber, respectively. The contents of Zn, Se, and Cu in high-pressured samples were significantly higher than that in the raw sea cumber (p < 0.01). The levels of Cd were all decreased after three thermal treatments. The intake of Zn and Cu increased in sea cucumber cooked by all thermal processes. While the bioaccessibility of Se and Cd decreased after cooking. A significant correlation was observed between the concentration and bioaccessibility of minerals. These data provide useful information for dietary risk assessments of minerals in sea cucumbers.
Changes of Collagen in Sea Cucumber (Stichopus japonicas) During Cooking
Xiuping Dong,Beiwei Zhu,Liming Sun,Jie Zheng,Dan Jiang,Dayong Zhou,Haitao Wu,Yoshiyuki Murata 한국식품과학회 2011 Food Science and Biotechnology Vol.20 No.4
Changes of the collagen in sea cucumber (Stichopus japonicas) during cooking were investigated. Crude collagen fibers (CCF) is more sensitive to heat than pepsin-solubilized collagen (PSC), absorbance at 226-232nm increased from 60 to 100^oC. PSC nearly completely degraded after cooking for 8-10 h, 4-6 h, 1-1.5 h, 40-50 min, and 10-20 min at 60, 70, 80, 90, and 100^oC,respectively. Collagen fiber shrinkage, disappearance of periodic cross striation, complete denaturation, and dispersion of denatured fibers at 40, 60, 80 and 100^oC,respectively, were demonstrated by transmission electron microscope (TEM). Above results might be instructional for sea cucumber processing and collagen usage.
Chune Liu,Lele Wu,Ying Xue,Feng Liu,Shan Sun,Liming Wang 한국식품과학회 2018 Food Science and Biotechnology Vol.27 No.3
In this study, the total concentration and bioaccessibility of four metals (Zn, Se, Cd, Cu) in sea cucumbers (Apostichopus japonicus) before and after cooking were measured. The concentration of Zn, Se, Cd, and Cu were 22.24 ± 0.75, 0.75 ± 0.06, 0.32 ± 0.07, and 1.88 ± 0.09 mg/kg in raw cucumber, respectively. The contents of Zn, Se, and Cu in high-pressured samples were significantly higher than that in the raw sea cumber (p\0.01). The levels of Cd were all decreased after three thermal treatments. The intake of Zn and Cu increased in sea cucumber cooked by all thermal processes. While the bioaccessibility of Se and Cd decreased after cooking. A significant correlation was observed between the concentration and bioaccessibility of minerals. These data provide useful information for dietary risk assessments of minerals in sea cucumbers.
Dongbo Bai,Wei Liming,Wei Chan,Qi Wu,Dan Huang,Shan Fu 제어로봇시스템학회 2015 제어로봇시스템학회 국제학술대회 논문집 Vol.2015 No.10
Sparse principal component analysis (SPCA) imposes extra constraints or penalty terms to the standard PCA to achieve sparsity. In this paper, we introduce an efficient algorithm for finding an effective sparse feature principal component (PC) of multiple physiological signals. The algorithm consists of two stages. In the first stage, it identifies an active index set with a desired cardinality corresponding to the nonzero entries of the PC. In the second one, it uses the power iteration method to find the best direction with respect to the active index set. Experiments on randomly generated data and multiple physiological signals datasets show that our algorithm is very fast, especially on large and sparse data sets, while the numerical quality of the solution is comparable to the state-of-art algorithm.