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      • KCI등재

        Protective effects of Hydro-alcoholic extract of the roots of Kasondi (Cassia occidentalis L.) against gentamicin-induced nephrotoxicity in albino Wistar rats

        Jwariya Shamim(Jwariya Shamim ),Athar Parvez Ansari(Athar Parvez Ansari ),Pankaj Goswami(Pankaj Goswami ),Seema Akbar(Seema Akbar ),Huzaifa Ansari(Huzaifa Ansari ),Abdul Wadud(Abdul Wadud ),Pervaiz Ah 셀메드 세포교정의약학회 2023 셀메드 (CellMed) Vol.13 No.6

        Objectives:Cassia occidentalis L. is a weed belonging to the Caesalpiniaceae family. The root of this medicinal plant is used for the treatment of various ailments, including kidney diseases. The present study was aimed at evaluating the nephroprotective effects of HAE of the roots of Cassia occidentalis L. against gentamicin-induced renal toxicity in albino Wistar rats. Methods:The renal toxicity was induced by subcutaneous administration of gentamicin at 100 mg/kg in the rats belonging to the disease control and treatment groups from the 4th to the 8th day. The rats in the treatment group received HAE of the roots of Cassia occidentalis L. at 67 mg/kg b. w. orally for 8 days, while no treatment was given to the rats in the disease control and plain control groups. At the end of the experiment, renal biomarkers viz; s. creatinine, b. urea, and s. uric acid, were investigated. The histopathological examination of the kidney specimens was also carried out. Results:The results of the present study revealed that renal function biomarkers such as s. creatinine, b. urea, and s. uric acid were significantly reduced in the rats of the treatment group as compared to those of the disease control group. Moreover, the histoarchitecture reports of the treatment group’s kidney specimens showed significant improvements. Conclusion:The results suggested that the HAE of Cassia occidentalis L. roots promisingly prevented kidney injury in gentamicin-induced nephrotoxic rats. This effect might be due to improved clearance of gentamicin from the renal tubule and decreased generation of reactive oxygen species (ROS).

      • KCI등재후보

        Study on the Quality of Market Dahi Compared to Laboratory Made Dahi

        A. L. Shekh,A. Wadud,M. A. Islam,S. M. E. Rahman,M. M. Sarkar,Tian Ding,Jae-Ho Choi,오덕환 한국식품위생안전성학회 2009 한국식품위생안전성학회지 Vol.24 No.4

        Dahi is yoghurt like fermented dairy products available in Bangladesh made by traditional ways from raw milk. The aim of the present study was to check and compare the present quality status of the market dahi in reference to laboratory made dahi. For this, dahi was prepared in the laboratory (A) and collected from Kishoregonj district (B), Gazipur district (C), Bogra district (D) and Dhaka district (E and F). Consumer acceptance quality was judged on 100 point by a judge panel and chemical and microbiological quality test were done by established methods. ‘A’ type dahi was superior followed by E, D, F, B and C considering the consumer acceptance quality parameter. From chemical test, it appears that, B possess the lowest pH (3.75 ± 0.05) and highest was in C (4.46 ± 0.15). Total solids content of F type dahi (318.40 ± 4.44 g/kg) was highest and fat (52.00 ± 2.00 g/kg), protein (44.33 ± 2.00 g/kg) and ash (10.76 ± 0.31 g/kg) content were also higher in F type dahi. E and A type dahi were also with considerable figure in chemical quality parameter. Dahi B was inferior in respect of microbiological quality- total viable count (TVC) (× 105 cfu/ml) content was 94.00 ± 4.58, yeast (cfu/ml) content was 183.33 ± 15.28 and mold (cfu/ml) content was 53.33 ± 15.28. The TVC (× 105 cfu/ml), yeast (cfu/ml) and mold (cfu/ml) content of A type dahi were 39.67 ± 4.51, 50.00 ± 10.00 and 20.00 ± 10.00, respectively. Considering all the three major quality aspects dahi A was superior than others followed by F, D, E, C and B. Dahi is yoghurt like fermented dairy products available in Bangladesh made by traditional ways from raw milk. The aim of the present study was to check and compare the present quality status of the market dahi in reference to laboratory made dahi. For this, dahi was prepared in the laboratory (A) and collected from Kishoregonj district (B), Gazipur district (C), Bogra district (D) and Dhaka district (E and F). Consumer acceptance quality was judged on 100 point by a judge panel and chemical and microbiological quality test were done by established methods. ‘A’ type dahi was superior followed by E, D, F, B and C considering the consumer acceptance quality parameter. From chemical test, it appears that, B possess the lowest pH (3.75 ± 0.05) and highest was in C (4.46 ± 0.15). Total solids content of F type dahi (318.40 ± 4.44 g/kg) was highest and fat (52.00 ± 2.00 g/kg), protein (44.33 ± 2.00 g/kg) and ash (10.76 ± 0.31 g/kg) content were also higher in F type dahi. E and A type dahi were also with considerable figure in chemical quality parameter. Dahi B was inferior in respect of microbiological quality- total viable count (TVC) (× 105 cfu/ml) content was 94.00 ± 4.58, yeast (cfu/ml) content was 183.33 ± 15.28 and mold (cfu/ml) content was 53.33 ± 15.28. The TVC (× 105 cfu/ml), yeast (cfu/ml) and mold (cfu/ml) content of A type dahi were 39.67 ± 4.51, 50.00 ± 10.00 and 20.00 ± 10.00, respectively. Considering all the three major quality aspects dahi A was superior than others followed by F, D, E, C and B.

      • KCI등재

        Analysis of the variations in the marker compound of Glycyrrhiza glabra L. root with reference to age of the drug, storage conditions and pharmacological efficacy

        Regu Iqra Akram,Wadud Abdul,Rahman Khaleequr,Jabeen Uzma 경희대학교 융합한의과학연구소 2022 Oriental Pharmacy and Experimental Medicine Vol.22 No.1

        Phyto-constituents and their efficacy vary with the age of the plant material and their affliction with environmental and storage conditions. Present study was conducted to evaluate the time dependent variation in physicochemical characters, glycyrrhi- zin content, microbial load and anti-inflammatory activity of Glycyrrhiza glabra L. root (GGR). Fresh GGR was dried and divided into three samples and stored as: sample A below 4 °C, sample B at room temperature and sample C at 40 ± 2 °C with relative humidity 75 ± 5% for six months. Afterwards, each sample was extracted in 50% alcohol and evaluated for phys- icochemical characters, glycyrrhizin content, microbial contamination and anti-inflammatory activity in histamine-induced inflammation in Wistar rats. Physicochemical characteristics exhibits less than 25% variation and qualitative analysis for plant metabolites exhibited similarity in all three samples. Glycyrrhizin was found more in sample C (5.07%) in comparison to sample B (4.52%) and A (4.72%) with variation less than 15%. As per the Ayurvedic Pharmacopeia of India these vari- ations in physicochemical parameters and glycyrrhizin content are insignificant. Sample A revealed total microbial count more than B and C. Accelerated stability data extrapolation of sample C suggests that shelf life of GGR is 2 years. Inflam- mation was significantly reduced by sample C followed by A and B in comparison to the control with residual paw volume of 0.9%, 3.22%, 20.4% and 29.7% respectively at 163 mg/kg BW dose. From the present study it can be concluded that up to two years age dependent variations in GGR is insignificant but its anti-inflammatory effect are glycyrrhizin dependent.

      • Skin detection using statistics of small amount of training data

        Shoyaib, M.,Abdullah-Al-Wadud, M.,Chae, O.,Byungyong, R. IET 2012 Electronics letters Vol.48 No.2

        <P>A skin detection approach based on combination of the statistics of multiple sources is presented. As long as the scarcity of available training data (with ground truth) is very common considering practical applications, such a fusion offers a much better classification of skin pixels compared to the state-of-the-art methods. Experiments on a renowned dataset result in a similar decision.</P>

      • KCI등재

        Study on the Quality of Market Dahi Compared to Laboratory Made Dahi

        Shekh, A.L.,Wadud, A.,Islam, M.A.,Rahman, S.M.E.,Sarkar, M.M.,Ding, Tian,Choi, Jae-Ho,Oh, Deog-Hwan The Korean Society of Food Hygiene and Safety 2009 한국식품위생안전성학회지 Vol.24 No.4

        다히(dahi)는 원유를 이용하여 방글라데시 전통 방법으로 발효시킨 요구르트와 비슷한 발효 유제품으로 본 연구는 실험실에서 만든 다히(dahi)와 시장에서 판매되고 있는 다히(dahi)의 품질을 비교하기 위하여 수행되었다. 실험실에서 준비한 다히(dahi)는 (A), Kishoregonj 지역에서 수집한 다히(dahi)는 (B), Gazipur 지역의 다히(dahi)는 (C), Bogra 지역의 다히(dahi)는 (D), Dhaka 지역의 다히(dahi)는 (E, F)로 각각 구분하였다. 소비자 만족 품질은 심사위원들에 의해 100점 만점으로 판단되었으며 화학적 미생물학적 품질 시험은 확립된 방법에 의해 수행되었다. 'A' 타입의 다히(dahi)가 소비자 만족 품질에 있어서 가장 우수한 것으로 나타났으며 그 다음으로 E, D, F, B, C 순으로 나타났다. 화학적 시험 결과, 'B'타입의 다히(dahi)가 가장 낮은 pH ($3.75\;{\pm}\;0.05$)를 나타냈으며 'C'타입의 다히(dahi)가 가장 높은 pH ($4.46\;{\pm}\;0.15$)를 나타내었다. 'F' 타입의 다히(dahi)의 총 고형물, 지방, 단백질, 회분이 각 각 $318.40\;{\pm}\;4.44\;g/kg$, $52.00\;{\pm}\;2.00\;g/kg$, $44.33\;{\pm}\;2.00\;g/kg$, $10.76\;{\pm}\;0.31\;g/kg$으로 가장 높게 나타났다. 'B'타입의 다히(dahi)에서 total viable count (TVC)는 $94.00\;{\pm}\;4.58\;cfu/ml$, 효모가 $183.33\;{\pm}\;15.28\;cfu/ml$, 곰팡이가 $53.33\;{\pm}\;15.28\;cfu/ml$로 미생물학적 품질 측면에서 가장 좋지 않은 것으로 나타났다. 'A' 타입의 다히(dahi)는 TVC, 효모와 곰팡이가 각 각 $39.67\;{\pm}\;4.51\;cfu/ml$, $50.00\;{\pm}\;10.00\;cfu/ml$, $20.00\;{\pm}\;10.00\;cfu/ml$로 나타났다. 3가지 주요 품질을 고려하였을 때 'A'타입의 다히(dahi)가 가장 우수하였으며 그 다음으로 F, D, E, C, B 순으로 나타났다. Dahi is yoghurt like fermented dairy products available in Bangladesh made by traditional ways from raw milk. The aim of the present study was to check and compare the present quality status of the market dahi in reference to laboratory made dahi. For this, dahi was prepared in the laboratory (A) and collected from Kishoregonj district (B), Gazipur district (C), Bogra district (D) and Dhaka district (E and F). Consumer acceptance quality was judged on 100 point by a judge panel and chemical and microbiological quality test were done by established methods. 'A' type dahi was superior followed by E, D, F, B and C considering the consumer acceptance quality parameter. From chemical test, it appears that, B possess the lowest pH ($3.75\;{\pm}\;0.05$) and highest was in C ($4.46\;{\pm}\;0.15$). Total solids content of F type dahi ($318.40\;{\pm}\;4.44\;g/kg$) was highest and fat ($52.00\;{\pm}\;2.00\;g/kg$), protein ($44.33\;{\pm}\;2.00\;g/kg$) and ash ($10.76\;{\pm}\;0.31\;g/kg$) content were also higher in F type dahi. E and A type dahi were also with considerable figure in chemical quality parameter. Dahi B was inferior in respect of microbiological quality- total viable count (TVC) (${\times}\;10^5\;cfu/ml$) content was $94.00\;{\pm}\;4.58$, yeast (cfu/ml) content was $183.33\;{\pm}\;15.28$ and mold (cfu/ml) content was $53.33\;{\pm}\;15.28$. The TVC (${\times}\;10^5\;cfu/ml$), yeast (cfu/ml) and mold (cfu/ml) content of A type dahi were $39.67\;{\pm}\;4.51$, $50.00\;{\pm}\;10.00$ and $20.00\;{\pm}\;10.00$, respectively. Considering all the three major quality aspects dahi A was superior than others followed by F, D, E, C and B.

      • Multiple object tracking with partial occlusion handling using salient feature points

        Naushad Ali, M.M.,Abdullah-Al-Wadud, M.,Lee, S.L. North-Holland [etc ; Elsevier Science Ltd 2014 Information sciences Vol.278 No.-

        Handling occlusion has been a challenging task in object tracking. In this paper, we propose a multiple object tracking method in the presence of partial occlusion using salient feature points. We first extract the prominent feature points from each target object, and then use a particle filter-based approach to track the feature points in image sequences based on various attributes such as location, velocity and other descriptors. We then detect and revise the feature points that have been tracked incorrectly. The main idea is that, even if some feature points are not successfully tracked due to occlusion or poor imaging condition, the other correctly tracked features can collectively perform the corrections on their behalf. Finally, we track the objects using the correctly tracked feature points through a Hough-like approach, and the object bounding boxes are updated using the relative locations of these feature points. Experimental results demonstrate that our method is proficient in providing accurate human tracking as well as appropriate occlusion handling, compared to the existing methods.

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