The Development of Protocols for Equitable Testing and Evaluation in Ocean Energy - A Three-Year Strategy

Ingram, David M.,Villate, Jose Luis,Abonnel, Cyrille,Johnstone, Cameron Korean Society for Fluid machinery 2008 International journal of fluid machinery and syste Vol.1 No.1

EquiMar (Equitable Testing and Evaluation of Marine Energy Extraction Devices in terms of Performance, Cost and Environmental Impact) is one of the first round of energy projects under the European Commissions 7th Framework Programme (FP7). The three year EquiMar project aims to deliver a suite of protocols for the evaluation of both wave and tidal converters, harmonizing testing and evaluation procedures across the wide range of available devices, accelerating adoption through technology matching and improving the understanding of both environmental and economic impacts associated with the deployment of devices. The EquiMar protocols will cover site selection, initial design, scaling up of designs, the deployment of arrays and environmental impact assessment as well as economic issues. EquiMar will build on existing protocols, e.g. UK DTI Marine Renewables Development Fund (MRDF) protocols for wave and tidal energy, and engage with international standards setting activities, e.g. IEC TC114.

APOLLO2 YEAR 2010

Sanchez, Richard,Zmijarevi, Igor,Coste-Delclaux, M.,Masiello, Emiliano,Santandrea, Simone,Martinolli, Emanuele,Villate, Laurence,Schwartz, Nadine,Guler, Nathalie Korean Nuclear Society 2010 Nuclear Engineering and Technology Vol.42 No.5

This paper presents the mostortant developments implemented in the APOLLO2 spectral code since its last general presentation at the 1999 M&C conference in Madrid. APOLLO2 has been provided with new capabilities in the domain of cross section self-shielding, including mixture effects and transfer matrix self-shielding, new or improved flux solvers (CPM for RZ geometry, heterogeneous cells for short MOC and the linear-surface scheme for long MOC), improved acceleration techniques ($DP_1$), that are also applied to thermal and external iterations, and a number of sophisticated modules and tools to help user calculations. The method of characteristics, which took over the collision probability method as the main flux solver of the code, allows for whole core two-dimensional heterogeneous calculations. A flux reconstruction technique leads to fast albeit accurate solutions used for industrial applications. The APOLLO2 code has been integrated (APOLLO2-A) within the $ARCADIA^{(R)}$ reactor code system of AREVA as cross section generator for PWR and BWR fuel assemblies. APOLLO2 is also extensively used by Electricite de France within its reactor calculation chain. A number of numerical examples are presented to illustrate APOLLO2 accuracy by comparison to Monte Carlo reference calculations. Results of the validation program are compared to the measured values on power plants and critical experiments.

APOLLO2 YEAR 2010

RICHARD SANCHEZ,IGOR ZMIJAREVIC,M. COSTE-DELCLAUX,EMILIANO MASIELLO,SIMONE SANTANDREA,EMANUELE MARTINOLLI,LAURENCE VILLATE,NADINE SCHWARTZ,NATHALIE GULER 한국원자력학회 2010 Nuclear Engineering and Technology Vol.42 No.5

This paper presents the most important developments implemented in the APOLLO2 spectral code since its last generalpresentation at the 1999 M&C conference in Madrid. APOLLO2 has been provided with new capabilities in the domain ofcross section self-shielding, including mixture effects and transfer matrix self-shielding, new or improved flux solvers (CPMfor RZ geometry, heterogeneous cells for short MOC and the linear-surface scheme for long MOC), improved accelerationtechniques (DP1), that are also applied to thermal and external iterations, and a number of sophisticated modules and tools tohelp user calculations. The method of characteristics, which took over the collision probability method as the main fluxsolver of the code, allows for whole core two-dimensional heterogeneous calculations. A flux reconstruction technique leadsto fast albeit accurate solutions used for industrial applications. The APOLLO2 code has been integrated (APOLLO2-A)within the ARCADIAreactor code system of AREVA as cross section generator for PWR and BWR fuel assemblies.APOLLO2 is also extensively used by Electricité de France within its reactor calculation chain. A number of numericalexamples are presented to illustrate APOLLO2 accuracy by comparison to Monte Carlo reference calculations. Results of thevalidation program are compared to the measured values on power plants and critical experiments.

Conservative approach of a symptomatic carious immature permanent tooth using a tricalcium silicate cement (Biodentine): a case report

Villat, Cyril,Grosgogeat, Brigitte,Seux, Dominique,Farge, Pierre The Korean Academy of Conservative Dentistry 2013 Restorative Dentistry & Endodontics Vol.38 No.4

The restorative management of deep carious lesions and the preservation of pulp vitality of immature teeth present real challenges for dental practitioners. New tricalcium silicate cements are of interest in the treatment of such cases. This case describes the immediate management and the follow-up of an extensive carious lesion on an immature second right mandibular premolar. Following anesthesia and rubber dam isolation, the carious lesion was removed and a partial pulpotomy was performed. After obtaining hemostasis, the exposed pulp was covered with a tricalcium silicate cement (Biodentine, Septodont) and a glass ionomer cement (Fuji IX extra, GC Corp.) restoration was placed over the tricalcium silicate cement. A review appointment was arranged after seven days, where the tooth was asymptomatic with the patient reporting no pain during the intervening period. At both 3 and 6 mon follow up, it was noted that the tooth was vital, with normal responses to thermal tests. Radiographic examination of the tooth indicated dentin-bridge formation in the pulp chamber and the continuous root formation. This case report demonstrates a fast tissue response both at the pulpal and root dentin level. The use of tricalcium silicate cement should be considered as a conservative intervention in the treatment of symptomatic immature teeth.

Conservative approach of a symptomatic carious immature permanent tooth using a tricalcium silicate cement (Biodentine): a case report

Cyril Villat,Brigitte Grosgogeat,Dominique Seux,Pierre Farge 대한치과보존학회 2013 Restorative Dentistry & Endodontics Vol.38 No.4

The restorative management of deep carious lesions and the preservation of pulp vitality of immature teeth present real challenges for dental practitioners. New tricalcium silicate cements are of interest in the treatment of such cases. This case describes the immediate management and the follow-up of an extensive carious lesion on an immature second right mandibular premolar. Following anesthesia and rubber dam isolation, the carious lesion was removed and a partial pulpotomy was performed. After obtaining hemostasis, the exposed pulp was covered with a tricalcium silicate cement (Biodentine, Septodont) and a glass ionomer cement (Fuji IX extra, GC Corp.) restoration was placed over the tricalcium silicate cement. A review appointment was arranged after seven days, where the tooth was asymptomatic with the patient reporting no pain during the intervening period. At both 3 and 6 mon follow up, it was noted that the tooth was vital, with normal responses to thermal tests. Radiographic examination of the tooth indicated dentin-bridge formation in the pulp chamber and the continuous root formation. This case report demonstrates a fast tissue response both at the pulpal and root dentin level. The use of tricalcium silicate cement should be considered as a conservative intervention in the treatment of symptomatic immature teeth.

Comparison of mechanical properties of a new fiber reinforced composite and bulk filling composites

Abouelleil, Hazem,Pradelle, Nelly,Villat, Cyril,Attik, Nina,Colon, Pierre,Grosgogeat, Brigitte The Korean Academy of Conservative Dentistry 2015 Restorative Dentistry & Endodontics Vol.40 No.4

Objectives: The aim of this study was to evaluate the mechanical and physical properties of a newly developed fiber reinforced dental composite. Materials and Methods: Fiber reinforced composite EverX Posterior (EXP, GC EUROPE), and other commercially available bulk fill composites, including Filtek Bulk Fill (FB, 3M ESPE), SonicFill (SF, Kerr Corp.), SureFil (SDR, Dentsply), Venus Bulk Fill (VB, HerausKultzer), Tetric evoceram bulk fill (TECB, Ivoclar Vivadent), and Xtra Base (XB, Voco) were characterized. Composite samples light-cured with a LED device were evaluated in terms of flexural strength, flexural modulus (ISO 4049, n = 6), fracture toughness (n = 6), and Vickers hardness (0, 2, and 4 mm in depth at 24 hr, n = 5). The EXP samples and the fracture surface were observed under a scanning electron microscopy. Data were statistically analyzed using one-way ANOVA and unpaired t-test. Results: EXP, FB, and VB had significantly higher fracture toughness value compared to all the other bulk composite types. SF, EXP, and XB were not statistically different, and had significantly higher flexural strength values compared to other tested composite materials. EXP had the highest flexural modulus, VB had the lowest values. Vickers hardness values revealed SF, EXP, TECB, and XB were not statistically different, and had significantly higher values compared to other tested composite materials. SEM observations show well dispersed fibers working as a reinforcing phase. Conclusions: The addition of fibers to methacrylate-based matrix results in composites with either comparable or superior mechanical properties compared to the other bulk fill materials tested.

Comparison of mechanical properties of a new fiber reinforced composite and bulk filling composites

Hazem Abouelleil,Nelly Pradelle,Cyril Villat,Nina Attik,Pierre Colon,Brigitte Grosgogeat 대한치과보존학회 2015 Restorative Dentistry & Endodontics Vol.40 No.4

Objectives: The aim of this study was to evaluate the mechanical and physical properties of a newly developed fiber reinforced dental composite. Materials and Methods: Fiber reinforced composite EverX Posterior (EXP, GC EUROPE), and other commercially available bulk fill composites, including Filtek Bulk Fill (FB, 3M ESPE), SonicFill (SF, Kerr Corp.), SureFil (SDR, Dentsply), Venus Bulk Fill (VB, HerausKultzer), Tetric evoceram bulk fill (TECB, Ivoclar Vivadent), and Xtra Base (XB, Voco) were characterized. Composite samples light-cured with a LED device were evaluated in terms of flexural strength, flexural modulus (ISO 4049, n = 6), fracture toughness (n = 6), and Vickers hardness (0, 2, and 4 mm in depth at 24 hr, n = 5). The EXP samples and the fracture surface were observed under a scanning electron microscopy. Data were statistically analyzed using one-way ANOVA and unpaired t-test. Results: EXP, FB, and VB had significantly higher fracture toughness value compared to all the other bulk composite types. SF, EXP, and XB were not statistically different, and had significantly higher flexural strength values compared to other tested composite materials. EXP had the highest flexural modulus, VB had the lowest values. Vickers hardness values revealed SF, EXP, TECB, and XB were not statistically different, and had significantly higher values compared to other tested composite materials. SEM observations show well dispersed fibers working as a reinforcing phase. Conclusions: The addition of fibers to methacrylate-based matrix results in composites with either comparable or superior mechanical properties compared to the other bulk fill materials tested.

Donor Islet Endothelial Cells in Pancreatic Islet Revascularization

Nyqvist, Daniel,Speier, Stephan,Rodriguez-Diaz, Rayner,Molano, R. Damaris,Lipovsek, Saš,a,Rupnik, Marjan,Dicker, Andrea,Ilegems, Erwin,Zahr-Akrawi, Elsie,Molina, Judith,Lopez-Cabeza, Maite,Villat American Diabetes Association 2011 Diabetes Vol.60 No.10

<P><B>OBJECTIVE</B></P><P>Freshly isolated pancreatic islets contain, in contrast to cultured islets, intraislet endothelial cells (ECs), which can contribute to the formation of functional blood vessels after transplantation. We have characterized how donor islet endothelial cells (DIECs) may contribute to the revascularization rate, vascular density, and endocrine graft function after transplantation of freshly isolated and cultured islets.</P><P><B>RESEARCH DESIGN AND METHODS</B></P><P>Freshly isolated and cultured islets were transplanted under the kidney capsule and into the anterior chamber of the eye. Intravital laser scanning microscopy was used to monitor the revascularization process and DIECs in intact grafts. The grafts’ metabolic function was examined by reversal of diabetes, and the ultrastructural morphology by transmission electron microscopy.</P><P><B>RESULTS</B></P><P>DIECs significantly contributed to the vasculature of fresh islet grafts, assessed up to 5 months after transplantation, but were hardly detected in cultured islet grafts. Early participation of DIECs in the revascularization process correlated with a higher revascularization rate of freshly isolated islets compared with cultured islets. However, after complete revascularization, the vascular density was similar in the two groups, and host ECs gained morphological features resembling the endogenous islet vasculature. Surprisingly, grafts originating from cultured islets reversed diabetes more rapidly than those originating from fresh islets.</P><P><B>CONCLUSIONS</B></P><P>In summary, DIECs contributed to the revascularization of fresh, but not cultured, islets by participating in early processes of vessel formation and persisting in the vasculature over long periods of time. However, the DIECs did not increase the vascular density or improve the endocrine function of the grafts.</P>