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Kellis is a small village in the Dakhlah Oasis in the Western Egyptian desert. From the perspective of spatiality, Kellis seems to epitomise isolation and remoteness, whereas from the perspective of language usage, Kellis seems to exemplify integration and mixture. The article aims to explain this paradox. In the context of Britain’s concept of spatiality, it investigates the linguistic landscape of Kellis therein focusing on three structures in semi-formulaic and formulaic contexts, that is the Greek wish for the addressee’s wellbeing, the Coptic Internal Address, and the Greek polite request, in addition to the Coptic variety of Kellis, that is dialect L*. The article traces non-idiolectal contact phenomena in formulaic contexts in order to zoom in on sociolectal variation, that is on markers rather than indicators in Labovian terms. Formulaic and semi-formulaic context are evidently approached differently from free contexts in speech production and comprehension. Based on the evidence discussed, the article concludes that the inhabitants of Kellis seem to represent a close-knit social network with a certain desire to demarcate themselves. With regard to their language(s), their spatial remoteness however prevented neither innovations nor the spread of aerial features.
Whilst companies try to attract talents through different means (e.g., financial incentives, flexible working hours), it is discussed that particularly high-quality candidates value information about a company’s ethicality. However, the influence of ethical market signals on talents’ intention to pursue with a job application is not well understood. Particularly in the digital context, it must be considered that companies can control some ethical market signals (e.g., ethical certifications in job advertisements), while others are beyond their control (e.g., ethical electronic word-of-mouth (eWoM)). The present study extends previous research related to job hiring by exploring how both signals affect talents’ job pursuit intention, and which factors mediate the influence of ethical market signals on job pursuit intention. To test the hypotheses, an online study was conducted with 265 university students. The results reveal that both types of ethical market signals increase an applicant’s job pursuit intention, although the effect appears to be stronger for eWoM. Furthermore, both signals enhance candidates’ willingness to apply for a job through affecting the attitude towards the advertisement and company employment image. Moreover, self-referencing is an additional mediator for the influence of eWoM on job pursuit intention. This suggests that candidates relate the information to their self-concept when others promote the ethicality of a company online. In summary, the present study helps to better understand how talents can be attracted to apply for a company, which positions itself as an ethical employer in the context of increasingly digitalized recruitment environments.
High quality and timely assessment feedback is central to student learning in higher education; however, written feedback has many limitations. One of the innovative approaches to delivering feedback to EFL learners is individualized audio-visual feedback (AVF) using screencast technology. Previous research on AVF has been extensively descriptive and mostly focused on student preferences for feedback and evaluation of various screencast software. The present study employed a mixedmethod design using pre-post writing tasks and pre-post questionnaires to investigate what particularly beneficial affordances this type of media-rich feedback might offer for writers in the English-Medium Instruction (EMI) classroom, to identify the effects of AVF on changes in learners’ motivation, and to explore students’ perceptions towards screencast feedback. The results suggest that AVF is positively received by EFL learners and that simultaneous visual cues and detailed explanations promote better understanding, engagement, and active listening. In addition, AVF significantly improves learners’ writing performance and academic motivation. The paper concludes with practical implications and suggestions for further research.
Background: Negative urine cultures to rule out urinary tract infections (UTI) generate a considerable laboratory workload; thus, a rapid screening test is desirable. We evaluated the performance of a new automated microscopy analyzer, cobas u 701 (Roche Diagnostics International, Rotkreuz, Switzerland) for the screening of UTI, and developed a rule-out strategy to reduce the number of samples requiring culture. We also assessed squamous epithelial cell (SEC) count as a predictor of culture contamination. Methods: In total, 1,604 urine samples from outpatients were analyzed with cobas u 701 and culture. Bacterial (BAC) and white blood cell (WBC) counts were used for sample interpretation. To determine a useful cut-off point to predict negative cultures, we selected the highest sensitivity and specificity values obtained from ROC curves. Diagnostic accuracy by age and gender was evaluated. Results: Urine culture showed growth of ≥104 colony forming units (CFU)/mL in 256 samples (16.0%). The highest sensitivity (91.8%) and specificity (68.4%) were obtained for cut-off points of 119 BAC/μL and 22 WBC/μL. The combination of BAC and WBC improved the performance of the rule-out strategy with a low rate of false-negative results (1.5%) and a high negative predictive value (NPV, 97.3%). Fifty-seven percent of the samples would not have required culture. SEC count was a poor predictor of culture contamination. Conclusions: cobas u 701 can substantially reduce the number of urine samples requiring culture, with a low false-negative rate and a high NPV.
( Victoria Sanchez-hellin ),( Antonio Galiana ),( Lucia Zamora-molina ),( Maria J. Soler-sempere ),( Justo Grau-delgado ),( Victor M. Barbera ),( Isabel Padilla-navas ),( Eduardo Garcia-pachon ) 한국미생물생명공학회(구 한국산업미생물학회) 2019 한국미생물·생명공학회지 Vol.47 No.3
This study was aimed at identifying the lower airway microbiota in patients with lung cancer (LC) using protected brush sampling. We enrolled 37 patients undergoing diagnostic bronchoscopy for suspected LC, 26 with LC and 11 with benign diseases. Protected brush specimens were obtained from the contralateral lung and the side of the tumor; these specimens were analyzed by 16S rRNA-based-next-generation sequencing. The results indicated that the biodiversity was not different between groups, and there were no significant differences between the proportion of microorganisms in the tumor and in the contralateral side of patients with LC. In patients with LC, there was a higher abundance of several microorganisms including Capnocytophaga, Haemophilus, Enterococcus, and Streptococcus; whereas, in individuals without LC, Bacteroides, Lactobacillus, or Methylobacterium were more abundant. Malignancy could be determined with an accuracy of 70% by isolating Enterococcus, Capnocytophaga, or Actinomyces. Microbispora indicated benignity with a sensitivity of 55%, specificity of 88%, and accuracy of 78%. Lower airway microbiota in patients with LC is fairly similar in both the tumor and contralateral sites. Endobronchial microbiota is different in patients with and without LC, and these differences may have a potential clinical value as diagnostic or prognostic biomarkers.
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis belong to a severe dermatopathic spectrum that includes frequently fatal mucocutaneous manifestations consisting of whole epidermal necrosis and sloughing with bullous transformation, blistering, and further skin detachment. Notably, cancer patients are at higher risk of developing SJS than the general population as a consequence of both the nature of neoplastic disease and frequent exposure to anticancer drugs. Ribociclib is a newly approved cycline-dependent kinase inhibitor that has been recently associated with a single case of SJS. We hereby present a case of ribociclib-related SJS. Early detection of threatening skin lesions is crucial to permit the immediate discontinuation of ribociclib given the predictable and unacceptable risk level. In cases of established SJS, early aggressive support should be initiated, ribociclib should be abruptly discontinued, and specific treatment based on actual evidence should be started.
Despite the recent expansion of English-medium instruction (EMI) in a non-English speaking educational context, few studies have investigated teaching methodology for EMI. Using a mixed method, this study examines the effects of teacher feedback on college students’ their perspectives of learning a business subject through EMI. The quantitative part of the study investigated questionnaire responses of two groups of students enrolled in a course on entrepreneurship: the control group of the lecture-style class offering little teacher feedback (n = 158) versus the experimental group featuring extensive feedback (n = 153). For the cross-examination of these quantitative results, a semistructured interview with four respondents followed. The analysis showed that the students’ disciplinary backgrounds (general studies, business, and engineering) create differences in their perspectives of EMI and learning the business subject. Among the three major groups, the business major students ranked English proficiency as the most important for their career purposes. The feedback-concentrated instruction contributed not only to learning the subject, but it also moderated the differences between the disciplines. Notably, the participants’ comprehension of the subject significantly correlated with their evaluation of EMI. These findings highlight the crucial effect of teacher feedback on acquiring discipline-specific knowledge and cultivating new perspectives of EMI.