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Α Β Γ Δ Ε Ζ Η Θ Ι Κ Λ Μ Ν Ξ Ο Π Ρ Σ Τ Υ Φ Χ Ψ Ω α β γ δ ε ζ η θ ι κ λ μ ν ξ ο π ρ σ τ υ φ χ ψ ω
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Ä Ö Ü ä ö ü ß
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½ ⅓ ⅔ ¼ ¾ ⅛ ⅜ ⅝ ⅞ ¹ ² ³ ⁴ ⁿ ₁ ₂ ₃ ₄
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      저자 : Thirunavukarasu Kalaivani (검색결과 2 건)
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        Physico-chemical and dielectric relaxation studies of ionic surfactants in Time Domain Reflectometry (TDR)

        Thirunavukarasu Kalaivani,Subramanian Krishnan,Subramanian Nithiyanantham 한국화학공학회 2017 Korean Journal of Chemical Engineering Vol.34 No.8

        The properties of aqueous surfactant solutions with external additives are extensively useful in surfactantbased systems. To study the dielectric relaxation studies of aqueous ionic surfactants (SDS, CTAB, DPC) and aqueous butanol, benzyl alcohol, aniline and tributylamine were carried out for different concentrations at 303k. Dielectric relaxation spectroscopy (DRS) is valuable for understanding the dynamic process mainly in micellar systems. Time domain dielectric data were obtained through HP54750A oscilloscope and TDR plug-in-module. The relaxation times were determined through the well-known Cole-Cole method. The superposition of two relaxation times gives the dielectric relaxation time obtained from the hydrated water molecule with rotations around the micelle, ions and another hydrophobic inner side of the micelle. Viscosity measurements were used to correlate the dielectric data. The Kirkwood correlation factor (gf), effective Kirkwood correlation factor (geff), Bruggeman Factor (fB), excess inverse relaxation time (1/τ)E, excess dielectric constant (ε E) and free energy of activation (ΔFt) were also calculated. The effects of dielectric relaxation and viscous flow were interpreted and discussed.

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        3D Structure Prediction of Human 5-Hydroxytryptamine Receptor 7 (5-HT7R)

        Thirunavukarasu Kalaivani 조선대학교 기초과학연구원 2018 조선자연과학논문집 Vol.11 No.2

        5-Hydroxytryptamine receptor 7 (5-HT7R) is one of G-Protein coupled receptors, which is found to be involved in the pathophysiology of various neurological disorders including depression, sleep disorders, memory deficiency and neuropathic pain. After activation of 5-HT7R by serotonin, it activates the production of the intracellular signaling molecule cyclic AMP. The availability of 3D structure of the receptor would enhance the development of new drugs. Hence, in the present study, homology modelling of human 5-hydroxytryptamine receptor 7 (5-HT7R) was performed using comparative modelling (Easy Modeller) and threading (I-TASSER) approaches. The generated models were validated using Ramachandran plot and ERRAT plot and the best models were selected based on the validation results. The 3D model developed here could be useful for identifying crucial residues and further docking study.

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