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Azeem Ullah,Sana Ullah,Tanzeel Areeb,Muhammad Umar,Phan Duy Nam,Rashid Masood,Soonjee Park,김익수 한국섬유공학회 2020 Fibers and polymers Vol.21 No.11
Polysaccharides from different sources have found their applications in the wound care for their inherent abilitiesof gelling, biocompatibility, biodegradability, and antibacterial activity. Considering the low cost, ease of processing,abundance in nature and therapeutic benefits of the polysaccharides we developed psyllium, alginate and chitosan (PAC)composite fibers and modelled their physical properties namely; tenacity, linear density and absorption in both distilled waterand saline solution; using Box-Behnken (BB) technique of Response Surface Methodology (RSM). The PAC fibers wereproduced using an in house developed wet spinning module; briefly the dope solutions containing psyllium and alginate wereextruded into a hydrolyzed chitosan and CaCl2. The produced fibers were acetone washed to remove the polar solvent; in thiscase water; and later dried in air. The present work aimed at the development of statistical models for physical properties:linear density, tenacity, antibacterial efficacy and liquid absorption; of the composite PAC fibers. The factors underconsideration were the raw material concentration namely; alginate and psyllium in dope solution and calcium chloride(CaCl2) and hydrolysed chitosan in the coagulation bath. The experimental work was designed and analyzed using Minitab®17 statistical software. Regression models using the under consideration factors were successfully developed.