제주도 지하수 질산염 농도의 시·공간적 변화 특성: 장기(1993-2015) 모니터링 자료의 평가

김호림(Ho-Rim Kim),오준섭(Junseop Oh),도현권(Hyun-Kwon Do),이경진(Kyung-Jin Lee),현익현(Ik-Hyun Hyun),오상실(Sang-Sil Oh),감상규(Sang-Kyu Kam),윤성택(Seong-Taek Yun) 대한자원환경지질학회 2018 자원환경지질 Vol.51 No.1

1993년부터 2015년까지 관측된 제주도 지하수 장기모니터링 관측정(N = 4,835)에서 수집된 지하수 수질자료(N = 21,568)를 기반으로 질산성질소의 시공간적 변동 특성을 평가하였다. 제주도 지하수의 질산성질소 농도의 중앙값은 2.5 mg/L로서 다른 국가나 대륙의 조사 결과에 비해 다소 높거나 유사한 것으로 나타났다. 또한 지하수 용도, 행정구역 및 고도 별로 유의한 차이를 보였다. 특히, 산간 지역에 비해 저지대 해안가에 위치한 농업 및 주거지역에서 농도가 높음을 확인하였다. Mann-Kendall 및 Sen’s slope 분석을 활용한 질산성질소 농도의 추세 분석 결과, 하류 저지 대에 비해 중산간지역에서의 질산성질소 농도 증가 경향이 뚜렷하였다. 제주도 내 토지 피복의 시계열 변화 특성과 결부 지어 보면, 중산간지역의 오염 증가 추세는 농업지역의 확장 등 인위적 활동 증가에 기인한 결과로 판단된다. 반면,기지정된 지하수자원특별관리구역에서는 전반적으로 질산성질소 농도의 감소 경향이 나타났는데, 이는 지하수 관리 측면에서 수질관리를 위한 적극적인 정책이 유효함을 시사한다. 본 연구에서는 제주도 지하수의 질산성질소 오염관리를 위한 적정 방안을 제안한다. The spatio-temporal variations of nitrate concentrations in groundwater of Jeju Island were evaluated by an analysis of time series groundwater quality data (N = 21,568) that were collected from regional groundwater monitoring (number of wells = 4,835) for up to 20 years between 1993 and 2015. The median concentration of NO 3 -N is 2.5 mg/L, which is slightly higher than those reported from regional surveys in other countries. Nitrate concentrations of groundwater in wells tend to significantly vary according to different water usage (of the well), administrative districts, and topographic elevations: nitrate level is higher in low-lying agricultural and residential areas than those in high mountainous areas. The Mann-Kendall trend test and Sen’s slope analysis show that nitrate concentration in mid-mountainous areas tends to increase, possibly due to the expansion of agricultural areas toward highland. On the other hand, nitrate concentrations in the Specially Designated Groundwater Quality Protection Zones show the temporally decreasing trend, which implies the efficiency of groundwater management actions in Jeju. Proper measures for sustainable groundwater quality management are suggested in this study.

환위험 가격결정의 시장별 차이와 컨트리펀드 프리미엄

권택호 여수대학교 2001 論文集 Vol.16 No.-

This study tests the difference of pricing of foreign currency risks between the Korean stock market and the New York stock market. Test results show that foreign currency risk is priced in the Korean stock market after foreign currency crisis. However, the foreign currency risk is not priced in the New York stock market during the same periods. These results means that the foreign currency risk is a systematic risk in Korean stock market, but the foreign currency risk is an unsystematic risk in New York stock market. This study result suggests that the Korean company exposed in foreign currency risk could increase its value by listing in the New York Stock Exchange.

충북지역 불임시술자에 관한 조사 연구

권호식,심운택 충남대학교 의과대학 지역사회의학연구소 1986 충남의대잡지 Vol.13 No.1

This study wasd designed to know the actual states of sterilization in Chungbuk Province. We analized total 580 persons who had Vasectomized and Laparoscopic tubal sterilized at the PPFK, Cheongju Clinic, from January 1984 to December, 1984. Following results were obtained. 1. An average age of Vasectomized group was 30.7 years, but that of Laparoscopic tubal sterilized was 28.3 years. 63.0% of Vasectomized group and 58.1% of Laparoscopic tubal sterilized group had two living children. 2. 84.0% of Vasectomized group was Vasectomized in spring and winter, but Laparoscopic tubal sterilized group revealed no seasonal preference. 3. Family planning worker's and Health worker's solicit, influence of mass communication, economic reasons were the main motivation of sterilization. 4. The highest rate of duration of marital life was 4-6 years in Vasectomized group, but that was 7 years or more in Laparoscopic tubal sterilization group. 5. The most common motive of accepting sterilization of farmer and merchant was Family planning worker's or Health worker's solieit, but that of clerical worker was influence of mass communication. 6. For the motivation of accepting sterilization, the rate of Family plainning worker's or Health worker's solicit was highest in rural residents, but that was influence of masscommunication in urban residents. 78.5% of Vasectomized person was cured within two weeks, but Laparoscopic tubal sterilized group, the rate was 75.5%. 7. 79,3% of Vasectomized person and 41.0% of Laparoscopic tubal sterilized person had no sequelae. 73.3% of Vasectomized person and 62.6% of Laparoscopic tubal sterilized person approved the sterilization for the Family planning method.

제지폐수처리용 생물고분자응집제를 생산하는 Bacillus sp. K-111의 배양특성조사

권기석,손용호,최선택,정석관,송숙희,김동걸 7개 국립대학교 환경연구 논문집 공동발행 위원회 2002 환경연구논문집 Vol.2 No.1

Flocculant-producing microorganisms were screened from obtained strains in the laboratory using a pulp-wastewater treatment as the flocculating agent. K-111 strain that had high flocculating activity among them was selected and identified as Bacillus sp. K-111 16s rDNA sequencing. The favorable medium for the production of flocculant was glucose 1.5%, NH_4NO_3 0.2%, tryptone 0.01%, K_2HPO_4 0.08%, KH_2PO_4 0.06%, CaCO_3 0.03%, MgSO_4·7H_2O 0.005%, MnSO_4 0.005% in 1 liter of D.W. at initial pH 7.0. The optimum culture temperature and pH were 30℃ and pH 7.0, respectively. the flocculating activity was observed most highly after 36 to 48 hr of cultivation at the optimum conditions. the flocculating activity of produced biopolymer on optimum conditions was about 2.5-fold higher than that of screening medium.

건강성인자원자에 있어서 Theophylline과 β_(2)-adrenergicagonists (Procaterol 및 Albuterol)의 약동학적 상호작용

신현택,권현명,김호순 숙명여자대학교 약학연구소 1998 약학논문집-숙명여자대학교 Vol.14 No.-

Theophylline and adrenergic β₂ -agonists are frequently used together in bronchial asthma and chronic obstructive pulmonary disease(COPD). Among the adrenergic β₂ -agonists, procaterol and albuterol are most frequently used with theophylline in Korean hospitals. The effect of procaterol and albuterol administration on pharmacokinetics of theophylline was studied in 11 normal healthy volunteers(6 males, 5 females). The theophylline clearances with and without /J-adrenergic agonist (procaterol) were 38.76 + 9.53 ml/kg/hr and 32.46 + 8.46 ml/kg/hr respectively, which were not statistically significant. Similar result was seen with albuterol. The values of AUC, T_(1/2), Ke and Vdss were not influenced by either procaterol or albuterol. Also, there was no significant change in cardiac output and heart rate. In conclusion, adrenergic β₂ -agonists (procaterol and albuterol) do not alter theophylline pharmacokinetics.

Starter 및 멸치액젓 첨가가 김치양념 및 겉절이 김치의 품질에 미치는 영향

최택권,박소희,유진현,임호수,조재선,황성연 한국식생활문화학회 2003 韓國食生活文化學會誌 Vol.18 No.2

양념에 Leu. mesenteroides, Lac plantarum의 젖산균과 멸치액젓 첨가가 김치 양념의 대장균군 제어, 속성촉진여부 및 관능적 특성에 미치는 영향을 조사하였다. Leu. mesenteroides과 젓갈을 첨가한 경우 초기 숙성이 촉진되나 후기 산패는 완만하였으며 Lac. plantarum의 첨가시에는 초기 숙성에는 큰 차이가 없고 후기 산패가 현저하게 진행되었다. 대장균군은 산도 0.80% 이상에서 사멸되었는데 leu. mesenteroides의 경우가 숙성이 촉진되어 보다 신속히 사멸시켰다. 총균수와 젖산균수는 초기에 starter 첨가구는 10^6CFU/mL 정도인데 반해서 starter를 첨가하지 않은 않은 처리구에서 총균수는 10^6CFU/mL , 젖산균수가 10^4CFU/mL 이었고 숙성 후에는 첨가균이 높은 수준을 유지하였다. 하지만 대체적으로 스타터의 첨가가 숙성 및 대장균에 크게 영향을 주지 못하는 경향으로 동일하게 나왔다. 관능적 특성에서는 Leu. mesenteroides 첨가구가 Lac. plantarum의 경우보다 우수하였다. 한편, 시판 겉절이 김치는 산도가 0.09~0.18%, ph 5.46~5.89, 총균수 2.2×10^6~3.1×10^7CFU/mL, 젖산균수는 2.1×10^4~6.6×10^5CFU/mL, 대장균수는 1.8×10^4~7.1×10^5CFU/mL, 염분 1.89%~2.51%으로 스타터 첨가 겉절이에 비해 ph와 염도를 제외한 품질 특성에서 전반적으로 낮은 값을 나타냈다. This study was performed in order to investigate the effect of Leuconostoc mesenteroides, Lactobacillus plantarum and salt fermented anchovy extracts on Kimchi sauce. The sauce was fermented more rapidly by addition of Leu. mesenteroids or salt fermented anchovy extracts on the early fermentation stage than the control, but it was fermented slowly on the late fermentation stage. When L. plantarum was added to the Kimchi on the early fermentation stage, the acidity of Kimchi didn't show a significant difference from the control, but acidity was remarkably increased on the late stage. Coliform group was disappeared when acidity of sauce was higher than 0.8% during fermentation. It was controlled by Leu. mesenteroides but not by L. plantarum. Total count and lactic acid bacterial count of the sauces with starter were 6.30×10^6~1.0×10^7 CFU/mL and 1.04~2.04×10^6 CFU/mL, respectively, but those of the control sauce were 10^6 CFU/mL and 10^4 CFU/mL, respectively. Those count of the sauce with starter were higher than those of the control sauce on the later stage of fermentation. Organoleptic quality of the sauce with Leu. mesenteroides was superior to that with L. plantarum.

다형성 교모세포종에서 광범위 전적출술후 단기 재발된 치험 1예

박호권,강중식,조준,문창택,장상근,임정애 건국대학교 의과학연구소 2003 건국의과학학술지 Vol.13 No.-

Glioblasty/ma Multiforme(GBM) is the one of the most common malignant tumors in central nervous system(CNS). The incidence of the tumor is about 12% of all CNS tumors and about 50% of all intracranial tumors. Though the development of the microsurgical technique, radiosurgical technique, and chemotherapy works effectively, complete cure of the GBM has not been achieved. It has been known that the prognosis of GBM depends on the extent of surgical tumor removal, remained tumor volume, radiation dose, and chemotherapy. Not only patient's age but also tumor characteristics such as MRI enhancement, angiogenesis and necrosis are also very important prognostic factors. Authors experienced very aggressive GBM in aged woman, who received gross total tumor removal, but refused other therapeutic motalities postoperatively. Very rapid recurrence of GBM and global cerebral edema in aged woman should be considered fatal. This case demonstrates the effectiveness of aggressive removal and the limited usefulness of neurosurgical tools in GBM recurrence. Authors would suggest that the early diagnostic effort and the verified neurosurgical therapy for malignant tumor are still strongly requested to make better prognosis.

불안장애환자가 나타내는 사고내용의 특성

원호택,신현균,박현순,권석만 서울大學校 社會科學大學 心理科學硏究所 1996 心理科學 Vol.5 No.1

본 연구는 인지내용이 정서장애에 영향을 미친다는 인지적 내용-특수성 가설에 근거하여 불안장애환자의 사고내용을 조사하고자 했다. 사고내용에 있어서, 불안장애 환자들이 정상인 또는 비불안 정신장애환자와 어떤 차이점이 있는지를 조사했으며 나아가서 불안장애의 하위유형인 공황장애환자와 비공황 불안장애환자간에 어떤 차이점이 있는지를 탐색하고자 했다.이를 위해서 공황장애환자 34명, 비공황 불안장애환자 24명, 비불안 정신장애환자 34명을 포함한 92명의 정신장애 환자와 60명의 정상인을 대상으로 하여 그들의 사고내용을 측정하였다. 이들의 사고내용은 불안민감성 척도(ASI), 광장공포인지 질문지(ACQ), 신체감각 질문지(BSQ)를 사용하여 측정되었다. 각 집단별 사고내용을 정밀하게 비교하기 위하여 각 척도의 개별문항에 대해서 차이비교검증을 실시하였다.본 연구의 주된 결과는 다음과 같다. 첫째, 공황 장애를 비롯해 불안장애 환자집단은 정상인 집단에 비해 세 척도에서 측정된 불안유발 사고내용을 현저하게 많이 가지고 있었다. 둘째, 공황장애 환자집단은 비불안 정신장애 환자(우울증 및 신체화) 집단에 비해 신체적 증상에 대해서 더 예민하고 이를 위협적인 것으로 평가하는 경향성이 있었다. 셋째, 공황장애 환자들은 비공황 불안장애 환자나 비불안 정신장애환자에 비해 극단적이고 파국적인 위험과 관련된 사고내용을 많이 가지고 있었다. 특히 공황장애 환자들은 다양한 신체적 증상과 변화에 예민하고 이를 죽음이나 통제상실상태와 같이 극단적이고 파국적인 것으로 해석하는 사고경향이 있는 반면, 비공황 불안장애 환자들은 대인관계에서의 부적절한 대처나 능력에 대한 부정적 평가와 같이 일반적이며 비파국적인 위험이나 위협과 관련된 사고내용을 많이 갖는 경향이 있었다.ABSTRACT The aim of the present study is to investigate some characteristics of patients with anxiety disorders in their thought contents from the theoretical perspective of the cognitive content-specificify hypothesis that cognitive contents influence emotional disorders. For this, differences in thought contents between patients with panic and non-panic anxiety disorder as well as between patients with anxiety disorders and non-anxiety psychiatric patients or nomal controls were examined.The data were collected from 92 psychiatric patients (34 panics, 24 non-panics, 34 non-anxiety psychiatric patients) and 60 normal controls. Their thought contents were measured with the Anxiety Sensitivity Inventory, Agoraphobic Cognition Questionnaire, and Body Sensation Questionnaire. The difference between groups in the individual item of the three measures was tested using ANOVA and multiple comparison tests.The main findings in the present study are as follows: First, the patients with anxiety disorders reported significantly more thoughts with anxiety-provoking contents than normal controls. Second, the patients with panic disorders tended to be more sensitive to physical symptoms and to interpret these as being threatening than the non-anxiety psychiatric patients. Third, the patients with panic disorder had more thoughts with contents related to extreme and catastrophic danger than those with non-panic anxiety disorders. In particular, those with panic disorder had strong tendency to be senstive to physical symptoms or changes and to interpret these as suggesting extreme and catastrophic danger such as death or loss of control, whereas those with non-panic anxiety disorders tended to have thoughts with contents related to general and non-catastrophic danger or threats such as inadequate coping in interpersonal situations or negative evaluation about their ability.

콩 종간교잡에서 주요형질의 유전분석

이정동,권택화,조호영,황영현 慶北大學校農業科學技術硏究所 2002 慶北大農學誌 Vol.20 No.-

재배종과 야생종의 인공교잡 분리세대에서 주요형질들의 변이와 유전력을 조사하여 야생종을 이용한 콩 품종육성의 기초자료를 얻고자 수행한 결과를 요약하면 다음과 같다. 두 인공교배의 F_2 집단에서 100립중을 제외한 나머지 조사 형질들은 초원분리를 보였다. F_1과 F_2의 평균 개화일수는 양친의 중간정도로 정규 분포를 보였다. 백립중의 F_1 평균은 은하콩, 소백나물콩 두 조합 각각6.5, 5.7g으로 소립종 쪽으로 치우친 정규분포를 보였다. F_2의 평균수량은 양친의 중간정도이었다. F_1의 덩굴성은 두 조합 각각 6.4, 6.6이었으며 F_2 평균은 은하콩 조합이 6.0으로 덩굴성 쪽으로 치우쳐 덩굴성이 부분적인 우성으로 보였으나, 소백나물콩 조합에서는 4.6으로 은하콩과는 다른 결과를 보였다. 경장, 개회일수, 개체당 협수, 수량, 도복, 덩굴성 등은 높은 광의의 유전력을 보였으며 100립중은 협의의 유전력이 은하콩 조합에서 52.3%, 소백나물콩 조합에서 65.6%로 평가되어 초기세대에서의 선발이 가능한 것으로 나타났다. This study was conducted to obtain the information of varietal development using wild soybean through investigation of variation and heredity of major agronomic characters in F_2 generation of interspecific cross between Glycine max and G. soja. In segregating populations of two crosses, all characters observed except 100-seed weight showed transgressive segregation. Days to flowering showed normal distribution; mean days to flowering in F_1 and F_2 was approximately mean of parent. Mean of F_1 for 100-seed weight was 6.2g and 5.7g for Eunhakong/KLG10084 and Sobaegnamulkong/KLG10084, respectively, which were somewhat skewed distribution to small seeded parent. Mean of F_2 was about mean of two parents. Degree of vine was 6.4 and 5.7 in F_1 for two crosses but it was 6.0 in F_2 for Eunhakong/KLG10084, which revealed the degree of vine as partial dominance while 4.6 for Sobasgnamulkong/KLG10084, somewhat different results from the previous cross. Broad-sense heritability(h^2B) for plant height, days to flowering, pods per plant, seed yield, and degree of vine was comparatively high and narrow-sense heritability(h^2N) for 100-seed weight which is the most important character in the development of small seed-size sprout soybean was 52.3% and 65.6% for Eunhakong/KLG10084 and Sobaegnamulkong/KLG10084, respectively, which indicated that selection for the character in early generation was possible.

유방암 환자에서 bcl-2 단백 발현의 예후 인자로서의 의의

류진우,박종권,정민,박동국,김정택,이두선,이찬영,전호진 단국대학교 1998 論文集 Vol.32 No.-

Breast cancer in women pose a problem, and it can be difficult at times to evaluate the possibility of the cancer recurrence in node negative early cancer. The reliable prognostic markers are needed in breast cancer management to help clinicians identify the patient with the high risk of recurrence and arrive at more rational decisions for proper treatment. In order to investigate the prognostic significance of bcl-2, an immunohis-tochemical staining was performed in 35 tissue sections from paraffin blocks of primary breast cancer. Bcl-2 positivity was 43%. No relation could be observed between bcl-2 expression and known prognostic factors(tumor size, lymph node metastasis state, histologic grade, and nuclear grade), There was strong relation between bcl-2 expression and estrogen receptor positivity (ER) (P〈0.05). No relation is found between bcl-2 expression and c - erbB - 2 expression. These results suggest that bcl-2 expression is associated with a favorable prognostic factor(ER) but it is of no value as independent prognostic factor to the clinician in identifying the patients with high risk of recurrence.