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        Administration of ketoprofen in postpartum sows to control the incidence of post-parturient disorders and improve piglet survival rate

        Suwicha Jeeraphokhakul,Thanabat Theerakulpisut,Pitchapa Khampoomee,Jakkrit Chaiwangna,Preechaphon Taechamaeteekul,Natchanon Dumniem,Junpen Suwimonteerabutr,Padet Tummaruk Asian Australasian Association of Animal Productio 2023 Animal Bioscience Vol.36 No.8

        Objective: Inflammation and pain management in postpartum hyperprolific sows is currently an important animal welfare issue in the swine industry. The present study investigates effects of ketoprofen treatment on the incidence of post-parturient disorders, feed intake, colostrum yield, piglet colostrum intake, colostrum immunoglobulin G (IgG) and piglet mortality rate during the first 3 days of postnatal life. Methods: In total, 61 Danish Landrace×Yorkshire crossbred sows and their offspring (n = 833) were included in the experiment. The sows were randomly distributed into two groups: i) control (n = 31), sows were treated with tolfenamic acid 2 mg per kg for 2 days postpartum; ii) ketoprofen (n = 30), sows were treated with ketoprofen 3 mg per kg for 2 days postpartum. The farrowing process of the sows was monitored for 24 h daily, and data associated with farrowing were collected. Piglet colostrum intake, sow colostrum yield and colostrum IgG were determined. Results: During the first 3 days postpartum, the incidence of sows that had fever did not differ between control and ketoprofen groups (51.6% and 56.7%, respectively, p = 0.692). Piglet colostrum intake did not differ between control and ketoprofen groups (p = 0.736). However, the proportions of piglets that had inadequate colostrum intake were 71.3%, 22.6%, and 5.4% in those with birth weights of <1.0 kg, 1.0 to 1.29 kg, and ≥1.30 kg, respectively (p<0.001). The piglet mortality rate did not differ between control and ketoprofen groups (p = 0.808). Conclusion: Administration of ketoprofen in postpartum sows for 2 days can control the evidence of post-parturient disorders in sows as effectively as the use of tolfenamic acid. No deleterious effect of ketoprofen was detected on sow colostrum yield, piglet colostrum intake and piglet mortality. Therefore, ketoprofen can be recommended as an alternative anti-inflammatory drug used in postpartum sows.

      • KCI등재후보

        Effect of Andrographis paniculata supplementation during the transition period on colostrum yield, immunoglobulin G, and postpartum complications in multiparous sows during tropical summer

        Tummaruk Padet,Petchsangharn Kankawee,Shayutapong Kanyakon,Wisetsiri Thanwarat,Krimtum Patcharin,Kaewkaen Sidthiphong,Taechamaeteekul Preechaphon,Dumniem Natchanon,Suwimonteerabutr Junpen,De Rensis Fa 아세아·태평양축산학회 2024 Animal Bioscience Vol.37 No.5

        Objective: This study evaluated the effect of Andrographis paniculata (A. paniculata) supplementation in sow diets before and after farrowing on the sow and piglets’ performances during early postpartum period and on sows’ backfat and longissimus muscle losses during lactation. Methods: Seventy Landrace×Yorkshire sows and their offspring (1,186 piglets) were distributed into three groups: control (n = 31), treatment–250 (n = 18), and treatment–1000 (n = 21). From 110.2±0.7 days of gestation until farrowing (5.8 days) and throughout the lactation period (25.2 days), sows in the control group were given the conventional lactation diet, while sows in the treatment–250 and treatment–1000 groups received supplements of 250 ppm and 1,000 ppm of A. paniculata, respectively. Results: In sows with parity 3–5, piglets from the treatment–1000 group had higher colostrum intake than the control and treatment–250 groups (p<0.05), but not in sows with parity 6–9. Colostrum immunoglobulin G (IgG) increased in treated sows versus controls for parity 6–9 (p<0.05), but was consistent for parity 3–5. Piglet performance until day 3 postnatal was similar across groups (p>0.05). Treatment–250 sows had higher feed intake post-farrowing than treatment–1000 sows (p<0.05). Longissimus loss was less in both treatment groups than control (p<0.05), but backfat loss was similar across groups (p>0.05). Post-partum complications were consistent across groups (p>0.05). Farrowing duration and piglet birth intervals in sows with parity 6–9 were prolonged in the treatment–1000 group. Conclusion: Supplementing with 1,000 ppm A. paniculata for 5.8 days pre-farrowing and 25.2 days post-farrowing enhanced sow colostrum IgG and piglet colostrum intake, while also reducing longissimus loss in sows. However, for sows of parity 6–9, this supplementation led to prolonged farrowing, increased intervals between piglet births, increased stillbirth, and reduced piglet birth weight. These effects should be considered when using A. paniculata supplementation.

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